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Overview

Amecide Forte Tablet

Manufacturer :  Synchem Lab
Medicine Composition :  Diloxanide, Tinidazole
Prescription vs OTC : Prescription by Doctor required

About Amecide Forte Tablet

Amecide Forte Tablet, an antiprotozoal agent, is the most effective medicine for the patients suffering from amoeba infections (mainly caused by Entamoeba histolytica). As far as health issues are concerned, this is one of the safest medicines.

Recommended dosage is 500mg three times a day for 10 days and the course may be repeated if needed. However excess dosage should be avoided. The mechanism of action of this medicine is, however, unknown. But, as it is a luminal amoebicide it is assumed to work by destroying the trophozoites of Entamoeba histolytica which then form into cysts and the cysts are then excreted out of the body.

The structure of this medication can be related to chloramphenicol as it acts by blocking protein synthesis. The furoate salt of this drug behaves as a prodrug which is metabolized in the gastrointestinal tract to produce diloxanide, the active drug. About 90% of each dose is excreted by urine and the rest through feces.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the uses of Amecide Forte Tablet

    • Parasitic Infections

    • Amebiasis

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the contraindications of Amecide Forte Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the side effects of Amecide Forte Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    Key highlights of Amecide Forte Tablet

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      This medication may be unsafe to use during pregnancy.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Does this affect kidney function?

      There is no data available. Please consult a doctor before consuming the drug.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    • What is the onset of action?

      The pharmacological action is initiated within 30 - 60 minutes after the administration of this medicine.

    • How long is the duration of effect?

      This medicine will remain active for about 4 - 5 hrs after its administration.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medication, please consult your doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    How does this medication work?

    This medicine used in treating protozoal infections like those by Entamoeba histolytica. It is a luminal amebicide that works by destroying trophozoites of the protozoa. Although the exact mechanism of action is still not clear, it is supposed to work by inhibiting protein synthesis.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

      FAQs about Amecide Forte Tablet

      • Ques : What is Amecide Forte Tablet?

        Ans : This medication an antiprotozoal agent, is the most effective medicine and very much safe as far as health issue is concerned

      • Ques : How long do I need to use Amecide Forte Tablet before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Amecide Forte Tablet?

        Ans : The recommended dosage is 500 mg three times a day for 10 days and the course may be repeated if needed.

      • Ques : Should I use Amecide Forte Tablet empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Amecide Forte Tablet?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Diloxanide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 10 December 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/diloxanide

      • Diloxanide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 10 December 2019]. Available from:

        https://www.drugbank.ca/drugs/DB08792

      • Diloxanide- WHO Model Prescribing Information: Drugs Used in Parasitic Diseases - Second Edition [Internet]. apps.who.int 1995 [Cited 10 December 2019]. Available from:

        https://apps.who.int/medicinedocs/en/d/Jh2922e/2.1.2.html

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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