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Overview

BNP Test

BNP Test

also known as: BNP , Brain Natriuretic Peptide

Brain natriuretic peptide (BNP) test is a blood test that counts the protein called BNP produced by your heart and blood vessels. These protein levels are higher than normal when there is a heart failure. A B-type natriuretic peptide or brain natriuretic peptide or BNP is a 32-amino acid-ringed peptide produced by the heart to normalize blood pressure and fluid stability. BNP is stored in and secreted predominantly from membrane granules in the heart ventricles, and is continuously released from the heart in response to both ventricle volume expansion and pressure overload. Other potential causes of elevated BNP levels include diastolic dysfunction, acute coronary syndromes, and hypertension with LVH, valvular heart disease, atrial fibrillation, and pulmonary embolism, pulmonary hypertension, sepsis, COPD, or hyperthyroidism.

If any patient is receiving biotin, the sample should not be taken until at least 8 hours after last biotin administration. Normal range for BNP is 0.5-30 pg/mL 3,4 If any patient has values between 100 pg/mL and 400 pg/mL it is an alarming sign and needs further investigation. Higher BNP levels indicate an alarming condition and chances of any serious disease.

BNP is useful to make a diagnosis of Heart Failure. Patients suffering from Dyspnea, BNP is a useful assay but should not be a used alone to make a diagnosis of HF. randomized, controlled, clinical trials. In patients with worsening HF, BNP or NT-proBNP is recommended in patients with dyspnea who are being evaluated for a diagnosis of acutely decompensated heart failure.

A small amount of blood will be taken from you. Then it’s placed in a machine that reads the level of BNP and NT-pro-BNP. The test takes about 15 minutes. The blood sample may have to be transported to a laboratory in some situations. Sample: Serum or plasma; 2 mL aliquot serum or plasma; minimum 0.5 mL Sample collection container: Stat/Line draws: 3 mL light-green-top (plasma separator) tube Routine requests/off-site specimens: 3.5 mL gold-top (serum separator) tube Sample stability: Room temperature three days; Refrigerated six days; frozen twenty-four months. Room temperature if transported to a laboratory. Specimen processing method: Serum should be allowed to clot. Centrifuge serum or plasma at 1100-2000 x g for 10 minutes at room temperature.

Specimen
Plasma, frozen
Volume
0.8 mL
Container
Lavender-top (EDTA) tube.
Type Gender Age-Group Value
Brain Natriuretic Peptide
Unisex
All age groups
100 - 300pg/ml
Average price range of the test is between Rs.1500 to Rs.3950 depending on the factors of city, quality and availablity.

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Popular Questions & Answers

She had high blood pressure 220-130. Her 2d echo test revealed as under:- E.A ratio reversed LVEF 65% Evidence of concentric left ventricular hypertrophy noted Evidence of Diastolic dysfunction present Please advise what it means and how serious it is?

MBBS, MD - Internal Medicine, DM - Cardiology, Cardiac Device Specialist (CCDS - Physician )
Cardiologist, Delhi
She had high blood pressure 220-130. Her 2d echo test revealed as under:-
E.A ratio reversed
LVEF 65%
Evidence of con...
Your Echo report is just showing the impact of high blood pressure on the heart, and even though it is not very serious at present, itis a sign that you should start getting treated for BP and get it under control or else it will keep harming other body organs as well. Consult a local cardiologist for proper evaluation of cause of BP and for starting treatment. Also start exercising daily, begin gradually, increase to 45 mins daily, avoid smoking, drinking and salt rich food and caffeine.
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Coronary Artery Disease (Heart Blockage)

MBBS, Dip.Cardiology, Fellowship in Clinical Cardiology(FICC), Fellowship in Echocardiology
Cardiologist, Ghaziabad
Coronary Artery Disease (Heart Blockage)

Coronary artery disease (CAD) is the most common type of heart disease. It is the leading cause of death in the United States in both men and women.

CAD happens when the arteries that supply blood to heart muscle become hardened and narrowed. This is due to the buildup of cholesterol and other material, called plaque, on their inner walls. This buildup is called atherosclerosis. As it grows, less blood can flow through the arteries. As a result, the heart muscle can't get the blood or oxygen it needs. This can lead to chest pain (angina) or a heart attack. Most heart attacks happen when a blood clot suddenly cuts off the hearts' blood supply, causing permanent heart damage.

Over time, CAD can also weaken the heart muscle and contribute to heart failure and arrhythmias. Heart failure means the heart can't pump blood well to the rest of the body. Arrhythmias are changes in the normal beating rhythm of the heart.