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Overview

Indclav 625 Tablet

Manufacturer :  Indchemie Health Specialities Pvt Ltd
Medicine Composition :  Amoxycillin, Clavulanic Acid
Prescription vs OTC : Prescription by Doctor not required

About Indclav 625 Tablet

Indclav 625 Tablet is prescribed for the treatment of otitis media, sinusitis, and infections caused by susceptible organisms involving the lower respiratory tract, skin and skin structure, and urinary tract. This is a combination medication that has Amoxycillin and Clavulanic Acid as active ingredients. Its spectrum is the same as amoxicillin with additional coverage of beta-lactamase.

The extended coverage Indclav 625 Tablet is due to its combination, which makes it a useful alternative when amoxicillin resistance is present and patients cannot tolerate alternative treatments.

Indclav 625 Tablet is an antibiotic belonging to the class of penicillin antibiotic that helps in the treatment of bacterial infections. The medicine works against the synthesis of the bacteria. It also treats conditions like gonorrhoea, tonsillitis, infection in the eye, middle ear or nose. It is important that you do not consume this tablet for cold, flu or other viral infections.

Symptoms of penicillin overdose include neuromuscular hypersensitivity (agitation, hallucinations, asterixis, encephalopathy, confusion, and seizures) and electrolyte imbalance with potassium or sodium salts, especially in renal failure.

Hemodialysis may be helpful to aid in the removal of the drug from the blood, otherwise most treatment is supportive or symptom directed.

Take entire prescription, even if you are feeling better. Take at equal intervals around-the-clock; may be taken with milk, juice, or food. You may experience nausea or vomiting (small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may help).

If using oral contraceptives, use additional contraceptive measures; amoxicillin may reduce the effectiveness of your oral contraceptive. Report rash; unusual diarrhoea; vaginal itching, burning, or pain; unresolved vomiting or constipation; fever or chills; unusual bruising or bleeding; or if the condition being treated worsens or does not improve by the time prescription is completed.

Also Read: Mezol Eye Drop Uses

    What are the uses of Indclav 625 Tablet

    What are the contraindications of Indclav 625 Tablet ?

    What are the side effects of Indclav 625 Tablet ?

    Key highlights of Indclav 625 Tablet

    • How long is the duration of effect?

      The effect of this medicine lasts for an average of 1.5 to 2 hours after onset of action.

    • What is the onset of action?

      The effect of this medicine can be observed within 1-2 hours of administration.

    • Are there any pregnancy warnings?

      This medicine does not cause any harm to the fetus, but there is no scientific evidence to certify it. Hence, it is best to consult a doctor before consuming it during pregnancy. It is best to be administered orally.

    • Is it habit forming?

      No habit forming tendencies have been reported.

    • Are there any breast-feeding warnings?

      This medicine can be given to the women who are breastfeeding but only after evaluating the benefits and risks with the doctor.

    • Is It safe with alcohol?

      It is assumed to be safe to consume alcohol while taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine affects the consciousness of the patient. Thus driving should be avoided while taking it.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose is needed, Kindly consult your doctor before taking it.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Adjustment of dose is needed, Kindly consult your doctor before taking it.

    What are the substitutes for Indclav 625 Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Indclav 625 Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      One should contact the doctor immediately if an overdose is suspected. Symptoms of an overdosage include convulsions, change in behaviour or a severe skin rash.

    How does this medication work?

    This medicine works via dual mechanism. Firstly, Clavulanic acid binds and inhibits beta-lactamases that inactivate amoxicillin resulting in amoxicillin having an expanded spectrum of activity. Secondly, Amoxicillin inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs); which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes (autolysins and murein hydrolases) while cell wall assembly is arrested.

      What are the interactions of Indclav 625 Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Lab Test

        Indclav 625 Tablet may interfere with urinary glucose tests using cupric sulfate (Benedict's solution, Clinitest); also it may inactivate aminoglycosides in vitro.
      • Interaction with Medicine

        Indclav 625 Tablet can interact with certain medicines or supplements to cause severe side effects. You must discuss the medicines you currently are taking with the doctor so that he/she can prescribe your substitutes.
        • Doxycycline, methotrexate, warfarin, ethinylestradiol and live vaccines are some of the medicines that interact with this medication to cause adverse side effects.
        • Decreased effect: Efficacy of oral contraceptives may be reduced.
        • Increased effect: Disulfiram, probenecid may increase amoxicillin levels, increased effect of anticoagulants.
        • Increased toxicity: Allopurinol theoretically has an additive potential for amoxicillin rash.
      • Interaction with Disease

        In patients with renal impairment, doses and/or frequency of administration should be modified in response to the degree of renal impairment; high percentage of patients with infectious mononucleosis have developed rash during therapy; a low incidence of cross-allergy with cephalosporins exists; incidence of diarrhea is higher than with amoxicillin alone. Hepatic dysfunction, although rare, is more common in elderly and/or males, and occurs more frequently with prolonged treatment.
      • Interaction with Food

        Indclav 625 Tablet may be taken with meals or on an empty stomach; may mix with milk, formula, or juice.

      FAQs about Indclav 625 Tablet

      • Ques : What is Indclav 625 tablet?

        Ans : Indclav 625 Tablet is a type of combination medicine which is used to treat a variety of bacterial infections. It contains Amoxycillin and Clavulanic Acid as working ingredients. Amoxycillin interferes with the growth and division process of the bacterial cell wall while clavulanic acid confirms increased antibacterial activity.

      • Ques : What is the use of Indclav 625 tablet?

        Ans : Indclav 625 Tablet is used for the treatment and prevention from conditions and symptoms of diseases like an ear infection, nose infection, throat infection and lower respiratory tract infection. Besides these, it can also be used to treat conditions like a skin infection, urinary tract infection, stomach ulcers, febrile neutropenia. The patient should inform the doctor about any ongoing medications and treatment before using Indclav 625 Tablet to avoid undesirable effects.

      • Ques : What are the side effects of Indclav 625 tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of Indclav 625 Tablet. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include allergic skin reaction, diarrhea, fever, joint pain, skin yellowing, and easy bruising or bleeding. Besides these, using this medicine can further lead to nausea or vomiting, altered sense of taste, convulsions and painful intercourse. If any of these symptoms occur often or on daily basis, a doctor should be urgently consulted.

      • Ques : For what treatment Indclav 625 tablet used for?

        Ans : Indclav 625 Tablet is a type of combination medicine which is used to treat a variety of bacterial infections. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects.

      • Ques : How long do I need to use indclav 625 tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : At what frequency do I need to use indclav 625 tablet?

        Ans : Indclav 625 Tab is generally used once or twice a day, as the time interval to which this medication has an impact, is around 12 to 24 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use indclav 625 tablet empty stomach, before food or after food?

        Ans : Indclav 625 is advised to be consumed orally. The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of indclav 625 tablet?

        Ans : Indclav 625 Tablet contains salts which are suitable to store between 20 to 25c temperature, as keeping this medication above that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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