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Overview

Prucalopride

Prescription vs OTC : Prescription by Doctor required

About Prucalopride

Prucalopride is an enterokinetic agent that helps to treat chronic constipation in women that is not due to any other medication or medical condition. It is usually used after all other laxatives have failed to provide relief from the situation.

This drug works by increasing the rhythmic wave like motion of the digestive system known as peristalsis. This helps to increase bowel movements. It is vital that you take your dosage according to your doctor’s instructions.

Do not use this drug if you are allergic to any of its ingredient. This medication should not be taken if you have or are:

  • Lactose intolerant
  • Glucose malabsorption
  • Kidney disease and
  • Intestinal disease.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the uses of Prucalopride

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the contraindications of Prucalopride ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the side effects of Prucalopride ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    Key highlights of Prucalopride

    • Is It safe with alcohol?

      Please consult doctor before consuming the drug.

    • Are there any pregnancy warnings?

      This medicine is extremely unsafe to be used during pregnancy. Doctor consultation is recommended in such cases.

    • Are there any breast-feeding warnings?

      The medicine should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Prucalopride, skip it and continue with your normal schedule. Do not double the dose.

    • Are there any overdose instructions?

      In case of overdose, consult your doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    Medicines containing Prucalopride

    Below is the list of medicines, which contains Prucalopride as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

    How does this medication work?

    This medication is a high affinity 5-HT4 agonist, which are associated with commencing peristalsis. Prucalopride changes colonic motility pattern through serotonin 5-HT4 receptor stimulation. It motivates colonic mass movement, which exerts a force while defecating.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

      What are the interactions of Prucalopride ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medication interacts with Albendazole, Erythromycin, Amiodarone and others.

      FAQs about Prucalopride

      • Ques : What is Prucalopride used for?

        Ans : Prucalopride is used to treat chronic constipation in women that are not due to any other medication or medical condition. It is usually used after all other laxatives have failed to provide relief from the situation.

      • Ques : Where is Prucalopride approved?

        Ans : Prucalopride is approved in India, Micronesia, and the USA.

      • Ques : Should Prucalopride be taken with a meal or without a meal?

        Ans : The effectiveness of Prucalopride does not depend on a meal, it can be taken either way.

      • Ques : Is Prucalopride safe for usage in paediatrics?

        Ans : Prucalopride is not recommended for usage in paediatrics as its safety and effectiveness are not verified.

      • Ques : Is Prucalopride safe for usage with contraceptive pills?

        Ans : Prucalopride should be used with caution with contraceptive pills as it may induce diarrhoea in some patients which make the contraceptive pills ineffective and cause unwanted pregnancy.

      • Ques : What is the onset of action of Prucalopride?

        Ans : Prucalopride usually takes about 2 to 3 hours to show its effect after administration.

      • Ques : What is the half-life of Prucalopride?

        Ans : The half-life of Prucalopride is approximately 18 to 20 hours.

      References

      • Prucalopride-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 11 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/prucalopride

      • Prucalopride-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 11 June 2022].Available from:

        https://go.drugbank.com/drugs/DB06480

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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