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Overview

Calpol 500 MG Tablet

Manufacturer :  Glaxosmithkline Pharmaceuticals Ltd
Medicine Composition :  Paracetamol
Prescription vs OTC : Prescription by Doctor not required

About Calpol 500 MG Tablet

Calpol 500 MG Tablet is a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis, and toothache, etc.

The active ingredient falls under the class of analgesics, belonging to the category of NSAID. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

  • You are allergic to this medicine.
  • You are suffering from a serious liver disorder.
  • You normally consume more than 3 alcoholic beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break, or mix it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

There are several drugs that may interact with Calpol 500 MG Tablet. Inform your doctor about all the other medications that you take including vitamins, minerals, prescribed drugs, over-the-counter drugs, and herbal products.

For adults Calpol 500 MG Tablet the general dose for fever and pain is 325-650 mg tablets once every 4 to 6 hours or 1000mg tablets once every 6 to 8 hours. It is advised to be guided by the doctor’s prescription and never to exceed the prescribed dosage.

For treating Calpol 500 MG Tablet toxicity, Acetylcysteine 140 mg/kg is administered orally (loading) followed by 70 mg/kg every 4 hours for 17 doses.

Therapy should be initiated based on laboratory analysis suggesting a high probability of hepatotoxic potential. Activated charcoal is very effective at binding acetaminophen.

Maintain adequate hydration (2-3 L/day of fluids unless instructed to restrict fluid intake). This medication will not reduce inflammation; consult the prescriber for anti-inflammatory, if needed.

    What are the uses of Calpol 500 MG Tablet

    What are the contraindications of Calpol 500 MG Tablet ?

    What are the side effects of Calpol 500 MG Tablet ?

    • Nausea Or Vomiting

    • Allergic Skin Reaction

    • Fatigue

    • Gastric / Mouth Ulcer

    • Anemia

    • Stevens-Johnson Syndrome (Sjs)

    Key highlights of Calpol 500 MG Tablet

    • How long is the duration of effect?

      The effect generally lasts for upto 6 hours at a stretch.

    • What is the onset of action?

      The medication shows effectiveness within 30 minutes after intake and the performance peaks within an hour, the effect lasts for about 6-7 hours before it starts to abate.

    • Are there any pregnancy warnings?

      This medication may harm the featus in some cases, consult your doctor for further risks and details..

    • Is it habit forming?

      No, the drug is not habit forming. But you should not exceed the prescribed amount of medication.

    • Are there any breast-feeding warnings?

      No there are no breast-feeding warning and it is considerably safe for lactating mother.

    • Is It safe with alcohol?

      This medication is not at all recommended with alcohol as the reaction with it can cause severe side effects, interaction can cause Gastrointestinal Bleeding, Jaundice, Vomiting, Joint Pain, Dizziness, and Rashes.

    • Is it safe to drive while on this medicine?

      This medicine does not show to effect your driving capabilities and therefore is safe to drive and operate heavy machinery after consumption of this medicine.

    • Does this affect kidney function?

      Dose adjustment is needed in case of renal impairment. Dosing interval in renal impairment:

      • Clcr 10-50 mL/minute: Administer every 6 hours.
      • Clcr <10 mL/minute: Administer every 8 hours (metabolites accumulate)
      • Hemodialysis: Moderately dialyzable (20% to 50%).
      Consult your doctor before taking this medication.

    • Does this affect liver function?

      Appears to be well tolerated in cirrhosis; serum levels may need monitoring with long-term use.

    What are the substitutes for Calpol 500 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Calpol 500 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you have missed the dose and are not able to bear the pain, you can take one tablet keeping the time different in time for the next dose. Do not take more than 4 gram or 6-7 tablets per day. Do not take more than one tablet per time.

    • Are there any overdose instructions?

      If you have overdose call the nearest emergency room as there are chances of you feeling Nauseous or Dizzy. Consult your doctor if you do not feel well.

    How does this medication work?

    Calpol 500 MG Tablet is a pain relief medication that is administered orally. It selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

      What are the interactions of Calpol 500 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        This medication is not at all recommended with alcohol as the reaction with it can cause sever side effects, interaction can cause gastrointestinal bleeding, jaundice, vomiting, joint pain, dizziness and rashes.

      • Interaction with Others

        5-HIAA Urine Test

        You may get a false-positive result for this test if you take Calpol 500 MG Tablet.
      • Interaction with Medicine

        One must take caution while taking this medicine. This medication may interact with other medication like Ketoconazole, Metformin, Anti-hypertensives if administered concomitantly. Also, Barbiturates, carbamazepine, hydantoins, sulfinpyrazone can increase the hepatotoxic potential of acetaminophen; chronic ethanol abuse increases the risk for acetaminophen toxicity; effect of warfarin may be enhanced.
      • Interaction with Disease

        The interaction of this medicine is severe with liver disease as it may impair liver functions. If the patient is an alcoholic then the medication should be avoided as the interaction causes severe side effects and may outweigh the intended purpose of the medication.

      • Interaction with Food

        May slightly delay absorption of extended-release preparations; rate of absorption may be decreased when given with food high in carbohydrates.

      FAQs about Calpol 500 MG Tablet

      • Ques : What is Calpol 500 mg tablet?

        Ans : Calpol tablet belongs to the medicine group that contains Paracetamol as main ingredient present. It is used for the treatment of muscle pain, and arthritis. Calpol 500 mg is prescribed to the patients having mild to modest pain. It also prevents Backache, Toothache, and Menstrual Cramps.

      • Ques : What is the use of Calpol 500 mg tablet?

        Ans : Calpol 500 mg is used to treat Post Immunization Pyrexia. It is also used for Painful Menstrual Bleeding. This tablet helps to cure Muscle cramps and controls Arthritis and Fever.

      • Ques : What are the side effects of Calpol 500 mg tablet?

        Ans : Calpol 500 mg has many common side effects such as Fever and vomiting. There are some serious side effects of this medicine like Fatigue, Mouth Ulcer and Bruising. In case of patients having any of the side effects or issues like anemia or Allergic reactions on skin. It is advised to stop the consumption of Calpol tablet and contact to doctor as soon as possible.

      • Ques : For what treatment Calpol 500 mg tablet used for?

        Ans : Calpol tablet is used to treat Muscle cramps. It is also used for Painful Menstrual Bleeding. Calpol 500 mg helps to cure Post Immunization Pyrexia. This medicine controls Arthritis and fever.

      • Ques : How long do I need to use calpol 500 mg tablet before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

      • Ques : At what frequency do I need to use calpol 500 mg tablet?

        Ans : This medication is generally used twice or thrice a day, as the time interval to which this medication has an impact, is around 6 to 8 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use calpol 500 mg tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken with the food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of calpol 500 mg tablet?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      • Ques : Is Calpol 500 MG Tablet an NSAID drug?

        Ans : No, this medication is not classified as an NSAID (Nonsteroidal anti-inflammatory drug). It is classified as a miscellaneous analgesic for mild to moderate pain and fever.

      • Ques : Can I take Calpol 500 MG Tablet with antibiotics?

        Ans : There are hundreds of antibiotics used to treat infections, so once you receive your prescription, ask your doctor or pharmacist if you can also take this medication at the same time that you take the antibiotic.

      • Ques : Can I take other medications along with Calpol 500 MG Tablet?

        Ans : Do not use any OTC for cough, cold, allergy, or pain medication without consulting your doctor or pharmacist. Calpol 500 MG Tablet contains many combination of medicines. If you use certain products together you may accidentally use too much of Paracetamol.

      References

      • Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

      • Anadin Paracetamol Tablets- EMC [Internet]. www.medicines.org.uk. 2016 [Cited 24 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/3875/smpc

      • Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Rohini DhillonMBA( CHA), MBBS, PGDMCHGeneral Physician
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