Ambulax 0.25 Mg/20 Mg Tablet

This Tablet is an effective drug prescribed to patients who have panic disorders and anxiety disorders as a result of depression. The drug controls the levels of certain unbalanced chemicals released by the brain in patients who suffer from depression.

This medication is a part of a group of medicines which go by the name of benzodiazepine in combination with beta blockers. This class of drugs work in a way through which they calm the brain and the central nervous system, preventing panic attacks.

Some side effects of the drug include

• Tiredness
• Feeling sleepy
• Memory issues
• Developing anxiousness
• Withdrawal symptoms

• Anxiety

• Panic Disorder

• Allergy

• Azole antifungal agents

• Severe Asthma And Breathing Problems

• Loss Of Coordination

• Drowsiness

• Abdominal Pain

• Difficulty Or Painful Urination

• Headache

• Chest Pain

• Sleeplessness

• Heartburn

• How long is the duration of effect?

  This medicine is excreted in urine and the effect lasts for a duration of 44 hours for an immediate release tablet and 52 hours for an extended release tablet / disintegrating tablet.

• What is the onset of action?

  The peak effect can be observed in 1 to 2 hours for an immediate release tablet, 1.5 to 2 hours for a disintegrating tablet and 9 hours for an extended release tablet.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women. Use only if clearly required under the supervision of the doctor.

• Is it habit forming?

  Habit forming tendency has been reported

• Are there any breast-feeding warnings?

  This medicine is known to excreted through human breast milk. It is not recommended for breastfeeding women.

Below is the list of medicines, which have the same composition, strength and form as Ambulax 0.25 Mg/20 Mg Tablet , and hence can be used as its substitute.

• Alltop P 0.25Mg/20Mg Tablet

  Ind Swift Laboratories Ltd

• Cardilax 0.25Mg/20Mg Tablet

  Intas Pharmaceuticals Ltd

• Pacinol 0.25 Mg/20 Mg Tablet

  Mankind Pharma Ltd

• Siron Plus 0.25 Mg/20 Mg Tablet

  Gujarat Terce Laboratories Ltd

• Pizolam P 0.25 Mg/20 Mg Tablet

  Psycormedies

• Alprop 0.25 Mg/20 Mg Tablet

  D D Pharmaceuticals

• Emlol A 0.25mg/20mg Tablet

  Tri Medix Pharma

• Cam Plus 0.25mg/20mg Tablet

  Mediez Pharma

• Beloc Plus 0.25Mg/20Mg Tablet

  Tripada Biotec Pvt Ltd

• Alpanol 0.25 Mg/20 Mg Tablet

  Numark Ltd

• Are there any missed dose instructions?

  If you miss a dose of this medication, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication, like other benzodiazepines, has a high affinity for the benzodiazepine binding site in the brain. It facilitates the inhibitory neurotransmitter action of gamma-aminobutyric acid, which mediates both pre- and post-synaptic inhibition in the central nervous system (CNS). This medicine also non-selectively blocks beta receptors sites in the heart, blood vessels, lungs and other organs. Thus pressure is lowered and blood flow in the heart and other organs is improved

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Acute alcohol intoxication

  Consumption of alcohol with this medicine is not recommended as it increases the risk of depression and breathlessness.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Cetirizine

  Use of this medication with cetirizine or levocetirizine should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

  Metoclopramide

  Use of this medication with metoclopramide should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

  Opioids

  Opioids like morphine, codeine, tramadol, hydrocodone or any cough preparations containing these medicines should be avoided when you are on this medication or other benzodiazepines. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and hypotension is necessary.

  Azole antifungal agents

  Azole antifungal agents like ketoconazole and itraconazole should be avoided when you are this medication due to the risk of increased concentrations of the medicine in the body which may cause increased sedation and changes in ECG. Inform the doctor if you are receiving these medicines when you are prescribed with this medication. If coadministration is needed then alternative medicines like lorazepam and oxazepam could be considered.

  Antihypertensives

  You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

• Interaction with Disease

  Glaucoma

  This medication is known to increase the fluid pressure inside the eye. It is contraindicated in acute narrow-angle glaucoma which is an eye disorder.

  Seizure Disorders

  The sudden stop of this medication may cause withdrawal effects and can precipitate seizures. The dose should be reduced gradually. Do not stop taking this medicine without consulting the doctor.

• Interaction with Food

  Grape fruit juice

  Grapefruit juice should be consumed with this medication. Alternatively, you can consume orange juice which does not affect the medicine.

• Alprazolam- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/alprazolam

• Important Information About Alprazolam- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 25 April 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-alprazolam/

• Propranolol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 25 April 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/propranolol

• Propranolol Tablets BP- EMC [Internet]. www.medicines.org.uk. 2019 [Cited 10 May 2019]. Available from:

  https://www.medicines.org.uk/emc/product/5888/smpc