5 Rarest Diseases In The World

Rare diseases affect a small percentage of the world’s population, and scientists are still trying to figure out what causes them and how to treat them. The majority of uncommon diseases are hereditary and many of them manifest themselves early in life. Although raising awareness can be difficult, there is a rare disease day observed every year on 28 February. 

Some of the rarest diseases in the world are:

Hutchinson-Gilford Progeria Syndrome

This condition is also known as progeria. It is caused by a deadly genetic abnormality that causes fast ageing beginning in childhood. The typical life expectancy is 13 years, with about 100 reported cases of patients living into their thirties. 

Stoneman’s Disease

Stoneman’s disease, often known as FOP (Fibrodysplasia Ossificans Progressive), is a rare condition caused by a mutation in the body’s healing system, which causes muscles, ligaments, and tendons to unsolicitedly stiffen, resulting in permanently frozen joints. 

Epidermodysplasia verruciformis

Treeman syndrome, commonly known as Epidermodysplasia Verruciformis, is a hereditary skin condition marked by abnormal vulnerability to human papillomaviruses or skin warts. Scaly growths on the hands and feet are the result of uncontrolled infections that arise between the ages of 1 and 20, though they can appear in middle age. This genetic mutation is thought to be caused by a change in zinc distribution regulation. 

Kuru

Kuru is a disease found only in a remote part of a new guinea in the fore tribe. The disease is caused by prions, a type of protein that causes aberrant brain tissue to form, resulting in gradual and irreversible brain damage. The disease is 100 per cent fatal, but you can only get it these days by eating the brains of the afflicted victims. Prior to the 1950s, the fore tribes' ceremonies included eating their deceased to retain their spirits, which frequently resulted in disease spread. Cannibalism is now illegal, hence the sickness is nearly non-existent. 

Foreign Accent Syndrome

Foreign accent syndrome causes people to speak in an unrecognizable dialect for no apparent reason. Only 60 cases have been documented so far. Doctors initially rejected it by calling it a mental issue, but in 2002 Oxford University, England scientists discovered that sufferers shared the same brain abnormalities, which resulted in alterations in pitch, speech, vowel lengthening, and other irreversible changes.