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Overview

U Frag 5000Iu Injection

Manufacturer: Bharat Serums & Vaccines Ltd
Medicine composition: Urokinase
Prescription vs.OTC: Prescription by Doctor required

U Frag 5000Iu Injection is a potent medication prescribed to combat and dissolve unnecessary blood clots that interferes with the smooth circulation of blood in the body. It prevents coagulation of blood. It is important to inform the doctor if you have a history of brain stroke or cardiac attacks. You cannot be recommended this drug if you suffer from brain tumours, active bleeding disorders in your body, have problems of blood clotting such haemophilia. It cannot be prescribed to you if you have very high blood pressure, if you have undergone a major surgery of your brain or spine or organ transplantation. You need proper diagnosis and monitoring of your health condition especially if you have suffered from kidney or liver disorders, bacterial endocarditis, blockages in your heart or if you have recently given birth or you are pregnant.

The medicine is administered through an injection provided by your doctor in a clinic. After the injection, your body vitals such as heartbeat, breathing rate, oxygen levels, blood pressure, and other essential systems are monitored in order to gauge your body’s response to therapy. You must consult the doctor as soon as possible in case you have an allergic reaction like skin rashes, hives, swelling of the mouth or throat.

In addition to its intended effect, U Frag 5000Iu Injection may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Decrease in blood pressure
Injection site bleeding.
Is It safe with alcohol?
Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?
Solokinase 500000iu injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Are there any breast-feeding warnings?
Solokinase 500000iu injection is probably unsafe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?
Caution should be used in patients with renal impairment.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?
If you miss a dose of Urokinase, please consult your doctor.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

What is thombroysis? N can a heart get another attack after 3 attacks n successful double bypass surgery ie valve replacement n artery bypass?

Diploma in Obstetrics & Gynaecology, MBBS
General Physician, Delhi
What is thombroysis? N can a heart get another attack after 3 attacks n successful double bypass surgery ie valve rep...
Thrombroysis is breaking a clot, immediately after a heart attack if thrombolytic medicines like streptokinase are given, it does help the afflicted person. 1st heart attack is like a shock when person asks himself -why me? it happens to others only! 2nd attack occurs if person is careless about food, high cholesterol and high bp & high sugar & higher weight are not under control, person keeps on smoking / gets exposed to pollution and low levels of oxygen in atmosphere does trigger a heart attack, no exercise or taking negative stress to the heart, everything that causes a heart attack has been ignored despite suffering from one, bypass surgery + valve replacement should work like a shock and one needs to reassure self that no more'encounters" with cardiac ot or exposure to everything that is not friends of heart except the doctors who do suggest annual check ups.
2 people found this helpful

Popular Health Tips

Taking Medicines during Pregnancy: Safe and Unsafe Medications

MBBS, DGO, MD - Obstetrics & Gynaecology, MRCOG
Gynaecologist, Delhi
Taking Medicines during Pregnancy: Safe and Unsafe Medications

Normal pregnancy lasts for 38 to 42 weeks. However, there may be times during these weeks that you may have some physical issues such as vomiting, backache, and loose stools etc which require treatment with medicines.

Therefore, monitoring and managing these physical conditions becomes necessary to ensure a normal delivery. Management consists of both medicines and rehabilitation. Medicines are considered to be the first line of treatment; however, the health care provider needs to take care while prescribing medicines during pregnancy taking into consideration the harmful effects they can have on both – the mother and the foetus.  Medicines pass on via the placenta from the mother to the foetus. Hence, before prescribing any medicine the provider should check the possibilities of the medicine causing any congenital defect. You should avoid medicines from the time of conception till the first 10 weeks, as this is the time when the foetus is most prone to the get permanent congenital deformities. Medicines given in the later stages (after 10 weeks) may cause systemic damage. For example NSAIDs (Non Steroidal Anti-Inflammatory Drugs) may lead to problems during labour or organ defects in the foetus.

Therefore, medicines should always be avoided during pregnancy. Still there are certain medicines, which can be taken but after consulting your physician. Let’s discuss the medicines that are safe during pregnancy.

The following is a list of medicines and their effects during pregnancy:

1. Analgesic Medicines

Paracetamol Safe
NSAIDs, such as aspirin May cause heart abnormalities in the third trimester

2. Opiates 

Codeine Effective in low doses
Hydrocodone Effective in low doses
Hydromorphone Effective in low doses

3. Anaesthetics 

Etomidate Unknown always ask your provider
Ketamine Avoid during the last trimester
Lorazepam Avoid for severe conditions, safe for short periods

4. Thrombolytics - The possible advantages of this class may balance the risk during pregnancy. Common medicines used are: Alteplase, Reteplase, Streptokinase, Urokinase.

5. Antidotes

Hydroxycobalamin antidote: cyanide Safe
Methylene blue antidote: methemoglobinemia Has a potential risk to the mother and foetus

6. Penicillins

First generation: penicillin G, benzathine penicillin, Bicillin, penicillin VK Safe
Second generation: oxacillin, dicloxacillin, nafcillin Safe

7. Cardiac agents

Adenosine Safe
Digoxin Not advised in third trimester
Lidocaine Safe

8. Diabetes: Insulin is safe to use during diabetes.

9. Antacids

Famotidine Low risk
Ranitidine Safe

10. Corticosteroids: Advised for short term use

Cetirizine Almost safe
Chlorpheniramine Safe

Always talk to your physician in case of any complication and before taking any medicine given above.

4 people found this helpful

Safe and Unsafe Medications to Take While Pregnant

MBBS, DGO, MD - Obstetrics & Gynaecology, MRCOG
Gynaecologist, Delhi
Safe and Unsafe Medications to Take While Pregnant

Which medicines are safe to use during Pregnancy?

Normal pregnancy lasts for 38 to 42 weeks. However, there may be times during these weeks that you may have some physical issues such as vomiting, backache, and loose stools etc which require treatment with medicines.

Therefore, monitoring and managing these physical conditions becomes necessary to ensure a normal delivery.Management consists of both medicines and rehabilitation.Medicines are considered to be the first line of treatment; however, the health care provider needs to take care while prescribing medicines during pregnancy taking into consideration the harmful effects they can have on both – the mother and the foetus.  Medicines pass on via the placenta from the mother to the foetus. Hence, before prescribing any medicine the provider should check the possibilities of the medicine causing any congenital defect. You should avoid medicines from the time of conception till the first 10 weeks, as this is the time when the foetus is most prone to the get permanent congenital deformities. Medicines given in the later stages (after 10 weeks) may cause systemic damage. For example NSAIDs (Non Steroidal Anti-Inflammatory Drugs) may lead to problems during labour or organ defects in the foetus.

Therefore, medicines should always be avoided during pregnancy. Still there are certain medicines, which can be taken but after consulting your physician. Let’s discuss the medicines that are safe during pregnancy.

The following is a list of medicines and their effects during pregnancy:

1. Analgesic Medicines

Paracetamol Safe
NSAIDs, such as aspirin May cause heart abnormalities in the third trimester

2. Opiates

Codeine Effective in low doses
Hydrocodone Effective in low doses
Hydromorphone Effective in low doses

3. Anaesthetics

Etomidate Unknown always ask your provider
Ketamine Avoid during the last trimester
Lorazepam Avoid for severe conditions, safe for short periods

4. Thrombolytics - The possible advantages of this class may balance the risk during pregnancy. Common medicines used are: Alteplase, Reteplase, Streptokinase, Urokinase.

5. Antidotes

Hydroxycobalamin antidote: cyanide Safe
Methylene blue antidote: methemoglobinemia Has a potential risk to the mother and foetus

6. Penicillins

First generation: penicillin G, benzathine penicillin, Bicillin, penicillin VK Safe
Second generation: oxacillin, dicloxacillin, nafcillin Safe

7. Cardiac agents

Adenosine Safe
Digoxin Not advised in third trimester
Lidocaine Safe

8. Diabetes: Insulin is safe to use during diabetes.

9. Antacids

Famotidine Low risk
Ranitidine Safe

10. Corticosteroids: Advised for short term use

Cetirizine Almost safe
Chlorpheniramine Safe

Always talk to your physician in case of any complication and before taking any medicine given above.

Table of Content

About U Frag 5000Iu Injection
When is U Frag 5000Iu Injection prescribed?
What are the side effects of U Frag 5000Iu Injection?
Key highlights of U Frag 5000Iu Injection
What are the dosage instructions?
What are the interactions for U Frag 5000Iu Injection?