Common Specialities
Common Issues
Common Treatments


Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Sitagliptin is a drug prescribed to patients with type 2 diabetes. It helps in reducing the blood sugar level in the body. It is classified under DDP-4 inhibitor class of medications. It is taken with diet and regular exercise and is sometimes prescribed along with other medications. It comes as a tablet and is consumed orally. However, note that it is used to lower blood sugar levels only and not to cure diabetes in itself.

Possible side effects of Sitagliptin include nausea, chills, seizures, dizziness, Anxiety, headache¸ fast heartbeat and slurred speech. It can also cause nightmares and cold sweats and severe skin reaction. Consult your doctor immediately if you notice any unusual effects. It can also cause some minor side effects like sore throat, sneezing, stuffy or runny nose or even cough.

Sitagliptin is not used for treating type 1 diabetes and is not advised for people with high blood ketone levels. You should consult your doctor before you use Sitagliptin if you are pregnant, breast-feeding, have any kidney problems. It is also not advised for people that have a history of conditions like gallstones, Angioedema or swelling of pancreas.

type diabetes

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Diabetologist before using this medicine.

  • Type 2 Diabetes

  • Is It safe with alcohol?

    Taking Sitagliptin with alcohol may affect blood glucose levels in patients with diabetes.
    Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
  • Are there any pregnancy warnings?

    Janumet xr cp tablet is probably safe to use during pregnancy.
    Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Janumet xr cp tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    It may cause hypoglycemia Exercise caution if you have to drive or operate a machinery.
  • Does this affect kidney function?

    No dose adjustment is needed for patients with the mild renal disease.Not advisable in patients with the moderate to severe renal disease.
    Use of this medicine should be avoided in patients with moderate to severe kidney disease. Please consult your doctor.
  • Does this affect liver function?

    No dose adjustment is needed for patients with the mild and moderate liver disease.Not advisable in patients with the severe liver disease.
    Should be used cautiously in patients with an underlying liver disease. Please consult your doctor.

Below is the list of medicines, which contains Sitagliptin as ingredient

View More

Sitagliptin is a hypoglycemic drug that works by competitively binding to and inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This inhibition increases the amount of active incretins (GLP-1 and GIP)

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Popular Health Tips

Table of Content
About Sitagliptin
What are the uses of Sitagliptin
What are the side effects of Sitagliptin ?
Key highlights of Sitagliptin
Medicines containing Sitagliptin
How does this medication work?