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Overview

Roles-D Capsule Sr

Manufacturer :  Sun Pharmaceutical Industries Ltd
Medicine Composition :  Domperidone, Rabeprazole
Prescription vs OTC : Prescription by Doctor not required

About Roles-D Capsule Sr

This medication is indicated for treating GERD (Gastro-esophageal reflux disease), which not responds to Rabeprazole medications alone. It prevents the tendency of vomiting and nausea in people suffering from gastrointestinal problems.

Roles-D Capsule Sr is a combination of Domperidone and Rabeprazole. The active ingredients, Domperidone and Rabeprazole fall under the class of dopamine antagonist and PPI (Proton pump inhibitor), respectively.

It is also prescribed to the patients of peptic ulcer and who take certain medicines for Parkinson’s disease. The medicine tightens the muscles near the entrance of the stomach and relaxes the ones present at the exit.

The action of this medication helps to speed up the passing of the food that you intake - from your stomach to your intestine, reducing the feeling of nausea and sickness, also preventing vomiting.

This medicine also works by blocking or reducing the stimulation in the ‘vomiting centre’ of your brain, which will eventually reduce the feeling of nausea and vomiting. The possible side effects of taking this medication can be headache, migraine, dryness of the mouth or breast pain.

You are advised not to take Roles-D Capsule Sr if you have the following conditions:

  • An allergy to Roles-D Capsule Sr or any other ingredient of this medicine
  • Bleeding problems or blockage in your stomach or in the intestine
  • Tumour in the pituitary gland
  • Cardiac disease
  • Incorrect levels of magnesium, potassium or calcium in the blood
  • Severe/moderate liver impairment

    What are the uses of Roles-D Capsule Sr

    • Gastroesophageal Reflux Disease

    • Peptic Ulcer

    What are the contraindications of Roles-D Capsule Sr ?

    • Allergy

    • Tumor Of Pituitary Gland

    • Heart Diseases

    What are the side effects of Roles-D Capsule Sr ?

    Key highlights of Roles-D Capsule Sr

    • How long is the duration of effect?

      The effect of this medication lasts up to 6 hours.

    • What is the onset of action?

      The peak effect of this medication can be observed within 30 to 60 minutes of administration.

    • Are there any pregnancy warnings?

      This medication does not cause any harm to the fetus, but there is no scientific evidence to certify it. Hence, it is best to consult a doctor before consuming it during pregnancy. It is best to be administered orally.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medication should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medication.

    What are the substitutes for Roles-D Capsule Sr ?

    Below is the list of medicines, which have the same composition, strength and form as Roles-D Capsule Sr , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Skip the missed dose and resume with the next scheduled dose at the right time. The dose should not get doubled in an attempt to make up for the missed dose.

    • Are there any overdose instructions?

      Contact your doctor if an overdose is suspected.

    How does this medication work?

    This medication attaches to the dopaminergic receptors without causing any release of the chemical dopamine. It, in turn, facilitates gastric emptying and decreases small bowel transit time. Also, it binds to H+/K+-exchanging ATPase in gastric parietal cells, resulting in blockage of acid secretion.

      What are the interactions of Roles-D Capsule Sr ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Lab Test

        The patients taking this medicine have been reported for false results, as it interacts with investigations of Neuroendocrine Tumors, Secretin Stimulation Test, Urine Tests for THC. Thus an alternative confirmatory test should be considered to verify the results.
      • Interaction with Medicine

        Concomitant use of Antiretrovirals, warfarin, methotrexate, digoxin, Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole, itraconazole), tacrolimus, antiarrhythmics, apomorphine, protease inhibitors, systemic azole antifungals, some macrolides (erythromycin, clarithromycin and telithromycin) is contraindicated.

      FAQs about Roles-D Capsule Sr

      • Ques : What is Roles-D Capsule Sr?

        Ans : This medication has Domperidone and Rabeprazole as active ingredients present. It performs its action by obstructing the release of acid in the stomach.

      • Ques : What are the uses of Roles-D Capsule Sr?

        Ans : This medication is used for the treatment and prevention from conditions and symptoms of diseases like duodenal ulcers, nausea, gastroesophageal reflux diseases, idiopathic gastroparesis, acid-related indigestion, and heartburn symptoms.

      • Ques : What are the Side Effects of Roles-D Capsule Sr?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of this medication. These include mouth dryness, weakness, flu, flatulence, stomach disorders, headache, abdominal pain, dizziness, and stomach pain.

      • Ques : What are the instructions for storage and disposal Roles-D Capsule Sr?

        Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      References

      • Domperidone- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 28 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/domperidone

      • Domperidone- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 28 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01184

      • Rabeprazole- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 28 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/rn/117976-89-3

      • Rabeprazole- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 28 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB01129

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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