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Overview

Rifagut 400 MG Tablet

Manufacturer :  Sun Pharma Laboratories Ltd
Medicine Composition :  Rifaximin
Prescription vs OTC : Prescription by Doctor not required

About Rifagut 400 MG Tablet

Rifagut 400 MG Tablet is primarily used to treat diarrhoea, It hinders the growth of the bacteria Escherichia coli (Travellers diarrhoea). It should be avoided if you are suffering from fever and are losing blood from your stool.

It is only effective for the treatment of bacterial infections, it is inefficient against viral and fungal infections. If used continuously it loses its effectiveness. Along with diarrhoea it is also used to treat irritable bowel syndrome. It may also help you think clearly.

Also, this medicine is also used to reduce the risk of improper functioning of the liver. However, this medication is only advisable for treatment if you are 12 years or above. While under medication you may experience some side effects like-

  • Nausea
  • Stomach Pain
  • Excessive Tiredness
  • Headaches
  • and Muscle tightening.

The medicine should be kept in a tight container and in a cool and dry place and out of reach of children.

This medicine is also prescribed when the patient is suffering from Hepatic encephalopathy, which is considered as a brain disorder, as the toxins present in the brain are not cleared out by the liver. The active ingredient in this medicine is Rifaximin.

Take exactly as directed, with meals. Avoid alcohol during and for 24 hours after last dose. With alcohol your may experience severe flushing, headache, nausea, vomiting, or chest and abdominal pain.

May discolor urine (brown/black/dark) (normal). You may experience "metallic" taste disturbance or nausea or vomiting (small frequent meals, frequent mouth care, chewing gum, or sucking lozenges may help).

Refrain from intercourse or use a barrier contraceptive if being treated for trichomoniasis. Report unresolved or severe fatigue; weakness; fever or chills; mouth or vaginal sores; numbness, tingling, or swelling of extremities; difficulty breathing; or lack of improvement or worsening of condition.

    What are the uses of Rifagut 400 MG Tablet

    What are the contraindications of Rifagut 400 MG Tablet ?

    What are the side effects of Rifagut 400 MG Tablet ?

    • Nausea Or Vomiting

    • Headache

    • Dizziness

    • Muscle And Joint Pain

    • Blurred Vision

    • Unusual Tiredness And Weakness

    • Fever

    Key highlights of Rifagut 400 MG Tablet

    • How long is the duration of effect?

      The effect generally lasts upto 6 hours.

    • What is the onset of action?

      Its shows its effectiveness in roughly within an hour but is the most efficient after 3 doses as it is poorly absorbed.

    • Are there any pregnancy warnings?

      If you are expecting or are planning on getting pregnant you should consult your doctor before you start this medication.

    • Is it habit forming?

      The medicine is not habit forming but its looses its effectiveness if consumed excessively.

    • Are there any breast-feeding warnings?

      It is known that this medication is excreted through human milk by lactating women, therefore it is not advisable at all to take this medication while breast feeding.

    • Is It safe with alcohol?

      If you are taking this drug you are alreading suffering from diarrhoea and liver disfunctions. Its not advisable for you to add fuel to the fire.

    • Is it safe to drive while on this medicine?

      Since many cases of drowsiness have been reported it is not deemed to be safe while driving. Though the tablet itself does not affect driving.

    • Does this affect kidney function?

      No, this does not affect kidney functions.

    • Does this affect liver function?

      Yes, it is know to alter the functioning of liver, this medication is meant to help the liver perform better.

    What are the substitutes for Rifagut 400 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Rifagut 400 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If the dose is missed it is advised not to double the intake the next time, however this may make the drug a little less effective.

    • Are there any overdose instructions?

      If the symptoms of overdose such as drowsiness, nausea and uneasiness is seen, visit the nearest doctor or emergency room.

    How does this medication work?

    This medicine works by inhibiting the process of RNA (Ribonucleic Acid) synthesis by binding with polymerase enzyme receptors and inhibiting the process of transcription.

      What are the interactions of Rifagut 400 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Not recommend for people who are suffering from liver diseases.

      • Interaction with Lab Test

        May interfere with AST, ALT, triglycerides, glucose, and LDH testing.
      • Interaction with Medicine

        The following class of medicines are to be avoided while under rifagut-400 medication, Amiodarone, Clarithromycin, Amoxicillin, Warfarin. Consult your doctor before taking a combination of medicines.

      • Interaction with Disease

        This medicines interact with some other medicines or interfere with treatments for other diseases. In turn, the efficiency of both medicines are reduced. If you have kidney or liver disease, or have certain types of allergies, this medicine will interfere with their treatment.

      • Interaction with Food

        The drug goes well with food as it in itself is low absorbant. Avoid taking it in empty stomach and food with high fat content.

      FAQs about Rifagut 400 MG Tablet

      • Ques : What is Rifagut 400 MG Tablet?

        Ans : Rifagut 400 MG is a medication which has Rifaximin as an active element present in it. This medicine performs its action by killing the ammonia-producing bacteria in the digestive tract. This treats your infection and relieves conditions of hepatic encephalopathy. This also helps in decreasing the recurrence of episodes of hepatic encephalopathy. Tablet is used to treat conditions such as Traveler's Diarrhea, Hepatic encephalopathy, Irritable bowel syndrome associated diarrhea.

      • Ques : What are the uses of Rifagut 400 MG Tablet?

        Ans : Rifagut Tablet is a medication, which is used for the treatment and prevention from conditions such as Traveler's Diarrhea, Hepatic encephalopathy, Irritable bowel syndrome associated diarrhea. The patient should inform the doctor about any ongoing medications and treatment before using Rifagut to avoid undesirable effects.

      • Ques : What are the Side Effects of Rifagut 400 MG Tablet?

        Ans : Rifagut 400 is a medication which has some commonly reported side effects. These side effects may or may not occur always and some of them are rare but severe. This is not a complete list and if you experience any of the below-mentioned side effects, contact your doctor immediately. Here are some side effects of Rifagut Tablet which are as follows: Black or Tarry stools, Difficult and painful breathing, Swelling of face, lips, eyelids, tongue, hands and feet , Watery and bloody diarrhea with stomach cramps and fever, Nausea and Vomiting, Headache, Blood in urine, Unusual bleeding or bruising, Ulcer and sore throat, Ringing or buzzing in the ears, Flatulence, Muscle and joint pain, Blurred vision, Mental Confusion, Dry mouth and lips, Dizziness and fainting, and Unusual tiredness and weakness. It is a list of possible side-effects which may occur due to the constituting ingredients.

      • Ques : What are the instructions for storage and disposal Rifagut 400 MG Tablet?

        Ans : Rifagut Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets. The patient should consult a doctor for its further uses and side effects and should inform the doctor about any ongoing medications and treatment before using to avoid undesirable effects. It is a prescribed medication.

      • Ques : Can Rifagut 400 Tablet be used for bacterial infections of intestine and liver failure?

        Ans : Yes, Rifagut tablet is a medication which can be used to treat conditions such as bacterial infections of the intestine and liver failure. Do not take Rifagut 400 mg for above-mentioned condition without consulting first with your doctor. It is a prescribed medication which should only be taken on a prescription.

      • Ques : How long do I need to use Rifagut 400 mg tablet before I see improvement in my condition?

        Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 to 3 days, before noticing an improvement in the condition. But the same duration is not mandatory for everyone and so, it is not a standard time period for this medication's action. Please consult your doctor, for the time period you need to consume this medication.

      • Ques : At what frequency do I need to use Rifagut 400 mg tablet?

        Ans : This medication is generally used twice or thrice a day, as the time interval to which this medication has an impact, is around 8 to 12 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.

      • Ques : Should I use Rifagut 400 mg tablet empty stomach, before food or after food?

        Ans : This medication is common to be taken orally and the action of salts involved in this medication, do not depend on whether taking it pre-meal or post-meal. It is advised to consult a doctor before use and take it at a fixed time in a day.

      • Ques : What does Rifagut 400 MG Tablet do for the liver?

        Ans : In liver disease, there is an increased growth of bacteria in the intestine which increases the load of toxins traveling through the body. This further increases the possibility of toxins reaching the brain which can cause abnormal brain function. This medication slows down the growth of bacteria in the gut, decreasing the symptoms in cases of liver disease.

      • Ques : Can Rifagut 400 MG Tablet cause weight gain?

        Ans : Usually, this drug does not cause weight gain. If there is a weight gain in your body, you should consult your doctor to determine the reason for weight gain.

      References

      • Rifaximin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 27 April 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/rifaximin

      • TARGAXAN 550 mg film-coated tablets- EMC [Internet]. www.medicines.org.uk. 2016 [Cited 27 April 2019]. Available from:

        https://www.medicines.org.uk/emc/product/2976/smpc

      • XIFAXAN- rifaximin tablet- Daily Med [Internet]. dailymed.nlm.nih.gov. 2018 [Cited 27 April 2019]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c5e8e2fd-7087-4b78-9181-cc259c0be2f1

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Rohini DhillonMBA( CHA), MBBS, PGDMCHGeneral Physician
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