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Refract 100 MG Tablet

Manufacturer: Crescent Formulations Pvt. Ltd
Medicine composition: Clozapine
Prescription vs.OTC: Prescription by Doctor required

Refract 100 MG Tablet works as an antipsychotic drug and controls the chemicals released by the brain to treat mental health problems like schizophrenia and other disorders. The drug is not easily available. Patients can get access to Refract 100 MG Tablet only from a certified pharmacy with a specific prescription.

Meant for oral consumption, the drug can be taken with food or without. Be sure to follow instructions as specified on the prescription. Do not take a lower or higher dose without consulting your doctor. You can take the tablet without water, just place it in your mouth and allow it to dissolve. In case you are prescribed only half a tablet. Break the tablet, consume one half and throw the other half away. Refract 100 MG Tablet is not meant to be stored once the tablet is removed from the blister pack.

All drugs lead to some side effects and so does Refract 100 MG Tablet. Dizziness, tremor in your hands and feet, a bit of weight gain, problems with vision, dry mouth, nausea and constipation are some common side effects of Refract 100 MG Tablet that you may experience. If you experience side effects like chest pain along with a serious case of dizziness, sudden coughing along with breathing issues, have a seizure or have any other new symptoms it is best that you seek medical help as soon as possible.

When it comes to dosage, your doctor may initially prescribe about 12.5 mg of Refract 100 MG Tablet to be consumed one or two times a day. Depending on your body’s reaction to the drug the doctor may gradually increase the dosage by 25 mg or 50 mg, until you reach to about 300 mg or 450 mg daily by week 2. The maximum dosage that an adult patient may be prescribed is about 900 mg. Do not discontinue Refract 100 MG Tablet suddenly as it can result in serious withdrawal symptoms.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.

Refract 100 MG Tablet is used in the treatment of schizophrenia. Delusions, hallucinations, reduced speaking are some of the symptoms of schizophrenia.
Avoid taking this medicine if you have a known allergy to Refract 100 MG Tablet or other antipsychotics.
In addition to its intended effect, Refract 100 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Blurred vision Major Common
Dizziness Major Common
Fast heartbeat Major Common
Shaking of the hands or feet Major Common
Constipation Major Common
Increased salivation Major Common
Anxiety Major Less Common
Dry mouth Major Less Common
Weight gain Major Rare
Acid or sour stomach Minor Common
Muscle pain Minor Less Common
Sore throat Minor Less Common
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 4 to 12 hours.
What is the onset of action?
The peak effect of this medicine can be observed in 1.5 to 2.5 hours.
Are there any pregnancy warnings?
This medicine should be used with caution in the pregnant women. Discuss with the doctor about benefits overweigh risks before using this medicine.
Is it habit forming?
No habit forming tendency has been reported
Are there any breast-feeding warnings?
This medicine is not recommended in breastfeeding women.
Below is the list of medicines, which have the same composition, strength and form as Refract 100 MG Tablet , and hence can be used as its substitute.
Torrent Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Micro Labs Ltd
Sun Pharma Laboratories Ltd
Linux Laboratories
Missed Dose instructions
Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructions
Seek emergency medical treatment or contact the doctor in case of an overdose.
United States
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Disease
Dementia Major
This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.
Interaction with Alcohol
Alcohol Moderate
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating machinery.
Interaction with Lab Test
Information not available.
Interaction with Food
Information not available.
Interaction with Medicine
Ketoconazole Major
Refract 100 MG Tablet should be used with caution with ketoconazole or other medicines that may cause irregular heart rhythm. Any symptoms of irregular heartbeat, breathing problem should be reported to the doctor immediately. Frequent monitoring of cardiac evaluation tests are to be performed. Suitable dose adjustments or an alternate medicine should be considered based on the clinical condition.
Tramadol Major
Tramadol may increase the risk of seizures when taken with Refract 100 MG Tablet. This interaction is more likely to happen in the elderly population, and in the patients suffering from head injury. Inform the doctor if you are on either of the medicines. An alternate medicine should be considered based on the clinical condition under the doctor's supervision.
The desired effect of antidiabetic agents may not be achieved when taken with Refract 100 MG Tablet. Regular monitoring of blood glucose levels is necessary. Inform the doctor if you develop any symptoms like excessive thirst, increased in the frequency of urination. Dose adjustments are to be made based on the clinical condition.
You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
Refract 100 MG Tablet belongs to the class atypical antipsychotics. It works by binding to the D2 and serotonin (5HT2A) receptors and inhibits the release of chemical substances thus helps in reducing the psychotic symptoms.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Blepharitis problem I'm my eyes lid. Dandruff in my eyes lid. What I do. Please suggest medicine.

ms ophthalmology
Ophthalmologist, Faridabad
Blepharitis problem I'm my eyes lid. Dandruff in my eyes lid. What I do. Please suggest medicine.
First get your vision checked for any refractive error. If any get a suitable spectacles. For blephritis you should first choose a gud anti dandruff shampoo. Then you should clean your lid margin with diluted johnsan baby shampoo (1 part of johnsan baby shampoo and 3 part of clean. 2 times a day and apply one eye ointment with trade name of Q SAP, or neosporine H.or occupol d.only on lid margin after cleaning. And review with me after 15 days. Coz eye ointment needs to be tapered or stopped.
1 person found this helpful

What is the best available eye drop for eyes from which water comes frequently. Thanks.

General Physician, Mumbai
What is the best available eye drop for eyes from which water comes frequently. Thanks.
Treatment depends on the cause and if it is due to infection than antibiotics are required and if it is due to allergy than anti allergic drops are required and also check for refractive error and follow up with reports.

Is lasik best for me as I am wearing glasses since 2006 today my age is about 23 and glasses create problem for me in getting a job. Please advice

Fellowship of the Royal College of Surgeons (FRCS)
Ophthalmologist, Ludhiana
Is lasik best for me as I am wearing glasses since 2006 today my age is about 23 and glasses create problem for me in...
LASIK is best for people above age of 18 year if the refraction is stable. You need to get cornea examinations (pentacam) done before you decide anything.
1 person found this helpful

I am suffering headache about 2 year. When wake up in morning the pain started. I have eye problem .kindly answer my question.

General Physician, Mumbai
I am suffering headache about 2 year. When wake up in morning the pain started. I have eye problem .kindly answer my ...
Few things regarding headache so that we can plan treatment accordingly 1) If pain is associated with blurred or decreased vision than check your eyesight for refractive error 2) If the pain is pulsatile in nature and with a throbbing pain usually with an aura than we have to rule out Migrane as the cause and 3) If the pain is associated with neck problems than we have to rule out cervical spondylosis as the cause 4) If the pain is associated with either a low or high BP or due to hyperacidity than we have to treat the cause after examination 5) If the pain is associated with cold and fever than we have to rule out sinusitis as the cause

I M 30 Year old I have mostly headache, and my eyes are likely burned. Some one says me that it is dryness in my eyes. What should I do?

Ophthalmologist, Nagpur
I M 30 Year old I have mostly headache, and my eyes are likely burned. Some one says me that it is dryness in my eyes...
Please get your eyes checked for refractive errors, smoking, avoid bright light. You can use Lubricating eye drops 3-4 times a day.
1 person found this helpful

Popular Health Tips

LASIK Eye Surgery - Facts About It!

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
LASIK Eye Surgery - Facts About It!

While spectacles are a fashion statement for some people, for others they are an uncomfortable necessity. Though contact lenses may be a little more aesthetically pleasing they too can be quite uncomfortable and cannot be worn throughout the day.

Thankfully, there is a third way to correct vision. Laser surgery or LASIK, it is a popular refractive procedure that can correct common vision problems, such as nearsightedness, farsightedness and astigmatism. This procedure aims at reshaping the cornea so that light entering the eyes can be focused onto the retina for the person to have a clearer vision. 

Laser surgery is pain-free and quick in most cases. Usually, it does not take more than 15 minutes to correct vision in both eyes. The results of this surgery can be seen in as little as 24 hours. 

The first step of laser surgery to correct vision is to create a thin, circular flap in the cornea. This is then folded back to access the stroma or underlying cornea. An excimer laser is then used to remove some of the corneal tissue. For people suffering from nearsightedness, the cornea is flattened while for people suffering from farsightedness, the cornea is made steeper.

In cases of astigmatism, an irregular cornea is smoothened. Once the correct gradient has been achieved the corneal flap is put back into place and the cornea is allowed to heal naturally. There are no stitches or bandages required in a laser eye surgery. You may feel a temporary burning or itching sensation in your eyes immediately after the procedure. It is important not to rub your eyes or place any pressure on them.

Your vision may also be cloudy or blurred for the first few hours. A doctor will usually advise you to rest for a few days after the surgery so that your cornea can heal properly. In a few days, your eyesight should stabilize, though, in a few rare cases, it may take a little longer. You should also avoid any form of strenuous exercising for a few days after the surgery. 

Though LASIK surgery has a very high success rate, there are very rare occasions where spectacles may still be needed even after the surgery. Thus LASIK is a choice of treatment for many who seek freedom from glasses.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5512 people found this helpful

Astigmatism - Ways They Can Be Diagnosed!

FAECS, DNB Ophtalmology, DO Ophthalmology, Fellowship In Phacoemulsification & Refractive Surgery
Ophthalmologist, Indore
Astigmatism - Ways They Can Be Diagnosed!

People may have weak eyes due to a variety of reasons. Astigmatism happens to be one of those reasons. When one is affected by astigmatism, it results in blurry vision. The eye has a part called the cornea, which is the outermost layer of the eye and is responsible for allowing light to enter. When the cornea is not shaped as it should be, it leads to astigmatism.

However, this is not the only condition under which it can occur. In fact, there are two different types of astigmatism. One is corneal astigmatism which is the result of an odd-shaped cornea. The other is lenticular astigmatism, which occurs when the lens has an incorrect shape. More often than not, people are born with astigmatism. However, there are chances of developing this eye disorder after an eye injury or after an eye disease.

How to diagnose?
There are a few ways in which astigmatism can be diagnosed.

  • One of the most popular methods is the visual acuity test. This measures the distance at which a letter is read clearly, as compared to what it should be.
  • Another way is by refraction. By placing lenses in front of the eyes, the way they focus light is measured.
  • The third way by which astigmatism can be detected is by keratometry, also known as topography. Light is focused on the cornea and the reflection is measured to find the curvature of that area.

Treatment options
The easiest way to go about treating astigmatism is by using corrective lenses. This is usually the method of treatment for people whose astigmatism is not that bad. The lenses could either be a part of spectacles or used as contact lenses. The good part about contact lenses is that the field of view is wider.

Orthokeratology (Ortho-k) works to improve astigmatism by using lenses as well. However, the lenses are of the hard variety. These lenses are useful for corneal astigmatism patients as they reshape the eye. Usually, they are worn while sleeping and most people can have normal vision the next day. However, if one stops using them, the eye goes back to its original state. So, they are not a permanent solution.

Surgery, however, can be a permanent solution to astigmatism. LASIK and PRK are two of the most popular types. RK is also popular, but to a lesser extent. It is good to remember that the risks of surgery should be discussed with a doctor prior to undergoing one. In case you have a concern or query you can always consult an expert & get answers to your questions!

2389 people found this helpful

Corneal Ulcer - Can It Lead To Blindness?

MBBS, MS - Ophthalmology
Ophthalmologist, Ghaziabad
Corneal Ulcer - Can It Lead To Blindness?

Antrior most transparent layer of the eye is called cornea. It is an extremely useful layer for refraction and protection of eye. Any trauma, foreign body or chemical etc can invade the integrity of this layer and can be invaded by bacteria, fungus or virus, resulting in the corneal ulcer. Sometimes, due to hypoxia induced by contact lenses too can result in a corneal ulcer.

Depending on clinical presentation, a doctor diagnoses the cause of the ulcer and start the therapy. Since the transparency of cornea is very important, a doctor starts very intensive therapy. With repeated frequent checkups if a proper and intensive therapy is not given, the ulcer can progress and can cause collection of pus in the anterior chamber which if not attended properly, can cause the infection to travel into the interior of the eyeball (vitreous chamber) resulting in total blindness. The ulcer can become deeper and lead to perforation of the cornea, causing severe damage to the eye and may require removal of pus (evisceration) or total removal of the eye ball.

Generally, fungal ulcers are more dangerous and occur mostly in rainy season.

  • It is imperative that a case of corneal ulcer is diagnosed promptly and very intensive treatment proper treatment is given to save the disfigurement of the eye and total irreparable blindness.
  • At times we have not only to give topical drops but oral therapy has to be given. Injections in the eye have to be given. Culture sensitivity has to be done in severe cases to identify the causative organism.
  • In extremely severe cases, we have to perform, therapeutic keratoplasty.

Conclusion: Corneal Ulcer is a serious challenging problem with the potentiality to cause total and irreparable blindness and must be attended promptly by a very expert ophthalmologist to save the eye. In case you have a concern or query you can always consult an expert & get answers to your questions!

5438 people found this helpful

LASIK: How LASIK Eye Surgery Works?

MBBS, MS - Ophthalmology, Diploma in Ophthalmology , Fellowship in Cornea and Anterior Segment
Ophthalmologist, Ahmedabad
LASIK: How LASIK  Eye Surgery Works?

LASIK or laser in situ keratomileusis, is a form of corrective surgery that help patients who are suffering from near sightedness (Myopia), far sightedness (Hypermetropia) and even astigmatism (cylindrical power in glasses). This procedure aims at correcting the shape of the cornea, which is the transparent layer that lines the front of the eye. Through this procedure, the cornea is reshaped so that the retina receives a focused light.

So what are the health tips for people going through a LASIK procedure? Here is our take:


Biggest advantage of LASIK is that it helps people to get rid of Glasses and contact lenses, which sometimes are cosmetically unacceptable and in some cases are visually disabling.

Best part of LASIK is that it is:

  • Quick (total duration of surgery is hardly 5 minutes) and virtually painless.
  • Has a high success rate ( success rate is 96%).
  • Does not require bandages or stitches.
  • Adjustments can be made years later to alter the vision as per growing impairment in the future and advancing years.

Risks/Side Effects:

Minor side effects like dryness, glare and halos, if appear, subside with time.

Eligibility Criteria:

Any person 18 yrs or older who fulfils the following criteria can undergo Lasik surgery

1. Stable refraction
2. Corneal thickness and topography should be in normal range
3. Dilated retinal examination should be normal
4. Adequately wet eyes

Note: One should abstain from wearing contact lens at least 2 weeks before the procedure.

Precaution after the Procedure:

Patient is likely to have some inflammation after the procedure and temporary dryness.

Use medicines as prescribed by the doctor

1. Avoid any type of eye makeup for at least 1 month after surgery
2. Avoid swimming or water sports for at least 2- 3 weeks after surgery

Going through a LASIK procedure is a matter of finding the right specialist and ensuring that you take all the precautions before the procedure. Also, it is important to look into your medical history and eyes in particular so as to avoid complications

13 people found this helpful

Refraction - Factors That Result in Abnormal Results!

MS - Ophthalmology, MBBS
Ophthalmologist, Noida
Refraction - Factors That Result in Abnormal Results!

Refraction is a test for eye examination, which measures prescription for eyeglasses or contact lenses for individuals. The test can be performed by either an ophthalmologist or optometrist or in layman terms, an eye doctor.

Procedure for the test
In this test, the individual sits on a chair, which has a special device attached to it, called the refractor or phoropter. The individual has to look through the device and properly focus on an eye chart which is exactly 6 meters or 20 feet away. This device has lenses of various strengths that can be moved into the individual’s view. The test is conducted on one eye at a time. The doctor will be asking the individual about the chart whether it appears clearer or less clear, thereby determining the refractory error of the eye.

No special preparation is required for this test and also this test does not cause any discomfort. The purpose of the test is to determine whether the individual has a need for glasses or contacts or not. In other words, it checks if the individual has a refractory error or not.

How can the results be inferred?
If the vision without glasses is normal, it means that the refractive index is zero and the vision should be 20/20. This means that one can read a one-centimeter letter at a distance of six meters.
If an individual has a refractive error, a combination of lenses will be required for a 20/20 vision. In case of a refractive error, there would be a prescription and that would have in it a series of numbers describing the power of the lens required to correct the vision.

Abnormal results can be due to the following reasons

  1. Myopia or near-sightedness (capability to see near objects clearly, but having difficulty in seeing objects far away)
  2. Hypermetropia or far-sightedness (capability to see far away objects clearly, but not the nearby objects)
  3. Astigmatism (blurred vision due to abnormally curved cornea)
  4. Presbyopia (inability to see nearby objects clearly, which usually occurs due to age)

Other reasons that cause abnormal results can be

  1. Macular degeneration causing loss of sharp vision
  2. Corneal infections or corneal ulcers
  3. Retinal detachment, which means separation of the retina from its supporting layers
  4. Retinitis pigmentosa or damage of the retina
  5. Blockage of a small artery carrying blood to the retina or retinal vessel occlusion

One should have an eye examination conducted every three to five years even if they suffer from no serious eye problem. However, after the age of 40, one should schedule eye appointments every year and have a test for refraction error of glaucoma conducted.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2486 people found this helpful

Table of Content

About Refract 100 MG Tablet
When is Refract 100 MG Tablet prescribed?
What are the contraindications of Refract 100 MG Tablet ?
What are the side effects of Refract 100 MG Tablet ?
Key highlights of Refract 100 MG Tablet
What are the substitutes for Refract 100 MG Tablet ?
What are the dosage instructions?
Where is the Refract 100 MG Tablet approved?
What are the interactions for Refract 100 MG Tablet ?