Prepulsid 10 MG Tablet

Manufacturer: Johnson & Johnson
Medicine composition: Cisapride
Prescription vs OTC: Prescription by Doctor required

Prepulsid 10 MG Tablet is prescribed for the treatment of heartburn in the case of patients who suffer from GERD, that is, gastro-esophageal reflux disease. The drug effectively increases the movement of the digestive tract. It includes the esophagus, stomach, and the intestines so that digestion becomes faster.

The drug also improves the function of the lower esophageal sphincter by making it stronger. The rate at which the stomach empties the digested food into the intestines also increases in the case of patients who are taking this drug.

Some serious health risks are related to the intake of this drug. Thus it is only prescribed to patients who have been unable to experience any relief from heartburn through lifestyle changes and other milder medication. It is meant to be taken orally, consume it about 15 minutes before a meal.

Before using this medication you should notify your doctor:

  • If you are allergic to it
  • If you have a stomach obstruction, heart disease, blocked arteries, irregular heartbeat, long QT syndrome running in the family, defect in heart structure, kidney and lung problems
  • If you are on other medication before
  • If you are pregnant women, those planning to conceive and breastfeeding mothers are advised not to take this drug as it can hurt the child

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Gastroenterologist before using this medicine.

The drug is utilised to fix the accompanying ailments

  • Hypersensitivity

  • Atrial Arrhythmias (Altered Heart Rate)

  • Qt Prolongation

  • Hypomagnesemia

  • Hypokalemia

A portion of the side effects caused by this drug

  • How long is the duration of effect?

    The effect of this drug lasts for an average duration of 7-10 hours.
  • What is the onset of action?

    The effect of this drug can be observed within 30-60 minutes of administration.
  • Are there any pregnancy warnings?

    Use of this drug in pregnant women is not recommended unless absolutely necessary. It should be used only if the potential benefits outweigh the associated risks. Consult your doctor before taking this drug.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    Use of this drug in breastfeeding mothers is not recommended. Breastfeeding should be discontinued if it is necessary to take this medicine. Consult your doctor before taking this medicine.
  • Is It safe with alcohol?

    No information available.
  • Is it safe to drive while on this medicine?

    No information available.
  • Does this affect liver function?

    No information available.

Below is the list of medicines, which have the same composition, strength and form as Prepulsid 10 MG Tablet , and hence can be used as its substitute.

  • Missed Dose instructions

    Take the missed dose as soon as you remember. The missed dose can be skipped if it is almost time for the next scheduled dose.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication acts by stimulating serotonin 5-HT4 receptors. Thus the level of acetylcholine at nerve endings is increased. As a result stomach muscle contraction and motility is increased.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Alcohol


    Reduce or minimize the uptake of alcohol while taking this medicine. Contact your doctor if any unwanted effects are observed.
  • Interaction with Lab Test


    Information not available.
  • Interaction with Medicine

    This medication interacts with Nefazodone, maprotiline, amprenavir, indinavir, nelfinavir, ritonavir, clarithromycin, erythromycin, troleandomycin, prochlorperazine, promethazine, quinidine, procainamide, and Warfarin.
  • Interaction with Food

    Grapefruit juice

    It is advised to not consume grapefruit juice in large quantities while taking this medicine as the likelihood of unwanted effects increase. Consult your doctor if an undesirable effect is experienced.

Ques: How long do I need to use Prepulsid 10 MG Tablet before I see improvement in my condition?

Ans: The drug should be consumed, until the complete eradication of the disease. It is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition.

Ques: At what frequency do I need to use Prepulsid 10 MG Tablet?

Ans: The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

Ques: Should I use Prepulsid 10 MG Tablet empty stomach, before food or after food?

Ans: This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

Ques: What are the instructions for the storage and disposal of Prepulsid 10 MG Tablet?

Ans: This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. The drug should be stored in a clean dry place, between 15-30 degrees Celsius.

Ques: What is Prepulsid 10 MG Tablet?

Ans: This drug is used in the treatment of heartburn, in the case of patients who suffer from GERD, that is, gastro-esophageal reflux disease. It effectively increases the movement of the digestive tract.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Prepulsid 10 MG Tablet
What are the uses of Prepulsid 10 MG Tablet
What are the contraindications of Prepulsid 10 MG Tablet ?
What are the side effects of Prepulsid 10 MG Tablet ?
Key highlights of Prepulsid 10 MG Tablet
What are the substitutes for Prepulsid 10 MG Tablet ?
What are the dosage instructions?
Where is the Prepulsid 10 MG Tablet approved?
How does this medication work?
What are the interactions of Prepulsid 10 MG Tablet ?
FAQs about Prepulsid 10 MG Tablet