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Overview

Negadix M Tablet

Manufacturer :  Adcock Ingram Healthcare Pvt Ltd
Medicine Composition :  Nalidixic Acid, Metronidazole
Prescription vs OTC : Prescription by Doctor required

About Negadix M Tablet

Negadix M Tablet helps in the treatment of bacterial infections. It also helps in the treatment of the urinary tract, tonsils, sinus, nose, throat, female genital organ, skin & soft tissues, and lungs (pneumonia).

You must not skip any doses and finish the full course of treatment even if you feel better. Immediately stop using Negadix M Tablet and inform your doctor if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Consult your doctor if you find blood in the stool or if you feel pain in your tendons, numbness, or tingling sensations. Women who are pregnant or breastfeeding must consult the doctor before consuming this drug.

Symptoms of overdose include nausea, vomiting, toxic psychosis, convulsions, increased intracranial pressure, metabolic acidosis; Severe overdose, intracranial hypertension, increased pressure, and seizures have occurred.

Avoid undue exposure to direct sunlight or use a sunscreen; take 1 hour before meals, but can take with food to decrease GI upset, finish all medication, do not skip doses; if persistent cough occurs, notify the physician.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Negadix M Tablet

    • Bacterial Infections

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Negadix M Tablet ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Negadix M Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Negadix M Tablet

    • Are there any pregnancy warnings?

      Pregnant women are advised to consult a doctor before consuming this drug.

    • Are there any breast-feeding warnings?

      Lactating mothers are advised to take medical help before consuming this medication.

    • Is it habit forming?

      No, the medicine is not habit-forming or addictive.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of the dose is needed. If Clcr <50 mL/minute: Avoid the use of Negadix M Tablet.

    • Does this affect liver function?

      Relevant information is not available. Please consult to know if any dose adjustment is needed in patients with liver impairment.

    • How long is the duration of effect?

      The duration of action of this medication is about 6 -7 hours.

    • What is the onset of action?

      The effect of this medicine is initiated within 1 - 2 hours after its administration.

    • Is it safe to drive while on this medicine?

      Yes, you can drive while on this drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the substitutes for Negadix M Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Negadix M Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      In case of an overdose, take medical help immediately.

    • Are there any missed dose instructions?

      It is advisable that you do not miss a dosage since there is just one dose per day. Consume the missed dosage as soon as you remember.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Negadix M Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    Being an antibiotic, it works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents bacterial cells from dividing and repairing, thereby killing them. This drug inhibits DNA polymerization in late stages of chromosomal replication.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Negadix M Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Using alcohol while taking this drug is not recommended. Any activity requiring a high level of mental alertness should be avoided in such cases.
      • Interaction with Lab Test

        False-positive urine glucose with Clinitest®, false increase in urinary VMA will be reported, if the patient is taking Negadix M Tablet.
      • Interaction with Medicine

        • Decreased effect with antacids containing magnesium, aluminum, or calcium, sucralfate, metal ions and didanosine. Avoid by 2 hours.
        • Increased effect of warfarin.
      • Interaction with Food

        Should be administered 1 hour before meals; can administer with food to minimize GI.
      • Interaction with Disease

        Use with caution in patients with impaired hepatic or renal function and prepubertal children. It has been shown to cause cartilage degeneration in immature animals. This drug may induce hemolysis in patients with G-6-PD deficiency. Use Negadix M Tablet caution in patients with a seizure disorder.

      FAQs about Negadix M Tablet

      • Ques : Does Negadix M Tablet effects the psychiatric treatment?

        Ans : It may rarely cause leukopenia. Use caution with clozapine and carbamazepine.

      • Ques : Does Negadix M Tablet effects the metal status of the patient?

        Ans : Dizziness and drowsiness are common. It may rarely cause confusion or psychosis.

      • Ques : What is Negadix M Tablet all about?

        Ans : Negadix M Tablet is an antibiotic. It is used for the treatment of diarrhea and dysentery. It is also used in infection of the urinary tract, tonsils, sinus, throat, female genital organ, skin & soft tissue and lungs.

      • Ques : How does Negadix M Tablet work?

        Ans : Negadix M Tablet works by stopping the action of a bacterial enzyme called DNA-gyrase. It prevents the bacterial cells from dividing and repairing, thereby killing them.

      • Ques : Can the use of Negadix M Tablet cause diarrhea?

        Ans : Yes, the use of this medication can cause diarrhea. It is an antibiotic which kills the harmful bacteria. This medication also affects the helpful bacteria in your stomach or intestine and causes diarrhea.

      • Ques : Can I stop taking the Negadix M Tablet when I feel better?

        Ans : It is advised to complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

      • Ques : At what frequency do I need to use Negadix M Tablet?

        Ans : This medication should be taken as prescribed by your health care expert.

      • Ques : Should I use Negadix M Tablet empty stomach, before food or after food?

        Ans : Take this medication empty stomach or at least 1 hour before meal or consult with your healthcare expert before you take this medication.

      • Ques : What are the instructions for the storage and disposal of Negadix M Tablet?

        Ans : This medication should be stored at room temperature. Store in a dry place. Keep this medication in a safe place and out of reach of children and pets.

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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