Tadalafil is a medicine that is used to treat sexual ailments in men. It is used to treat symptoms like erectile dysfunction and sexual impotence. It does this by increasing the amount of blood that ultimately reaches the penis. This medicine works by relaxing the muscles around the genital area of men. It does this by preventing Phosphodiesterase-5 from working on the body. This further increases the amount of cyclic guanosine monophosphate (cGMP) present in the body, which ends up relaxing smooth muscles inside blood vessels.
This medicine can also be used to treat problems of the prostrate gland and of passing urine. However, it will not help you in protection against and treatment of sexually transmitted diseases like syphilis. This medicine does not require a doctor’s prescription, but you should talk to a urologist about the dosage you specifically require, as any kind of overdose may be extremely dangerous. It may even cause death. Before you obtain the dosage, make sure to inform your doctor of your medical history and of any drugs you are currently taking. After the prescription, you may take this medicine with or without food and resume sexual activity after about 60 minutes of consumption.
This medicine is prescribed in cases of erectile dysfunction which makes having intercourse difficult for males. Sexual stimulation combined with this medicine can help sustain an erection. Also, it is prescribed for benign prostatic hyperplasia(enlargement of the prostate which makes urinating troublesome), and in cases of extraordinarily high blood pressure in blood vessels of the lungs and right side of the heart.
This medicine should not be used by you if you have had allergy or increased sensitivity to it or its active components in the past.
This medicine should be consumed 2 hours before any sexual activity at the least. The effects of this medicine may persist in your body for about 3 days.
The onset period of this medicine varies according to the mental health and state of the user. The average onset of action is about 2 hours after oral administering of the medicine.
This medicine does not exhibit habit forming tendencies.
Alcohol is not recommended when you are using this medicine. The combination of it with alcohol may cause symptoms like dizziness, exhaustion, lack of focus or understanding, and pains in your head. These, if caused, should be immediately reported to your physician.
This medicine is not advisable to be used when you are pregnant. You must seek medical attention to help you in determining the dosage if you absolutely cannot do without it.
This medicine can absolutely not be used by mothers who are lactating. You should use some other medicine as replacement when you are breastfeeding.
Sufficient information is not available on whether you can drive while on this medicine. Lack of focus caused by this medicine varies from person to person, so you should not drive or operate heavy machinery if you feel drowsy yourself after consuming this drug.
This medicine is not recommended for patients of kidney disease. If you have a less intense degree of kidney disease, you may still take a very muted dose of this medicine, but if your kidneys don’t function at all, you may be prohibited from taking this medicine. Speak to your doctor before you go ahead, in any case.
If you have intense liver disease, you are asked to not take this medicine. You can have lesser doses if your liver ailment is less serious. Consult your doctor before taking any action.
If you have forgotten the timing of a dose, and hence happen to have skipped it, take it as soon as you remember. However, if you are due for your next dose at the time, skip the missed dose altogether.
If you notice symptoms of an overdose, you should seek your doctor’s help immediately.
This medicine interacts with diseases like heart disease, increased blood pressure, ailments of the liver and kidney, seizure disorder and abnormal erections.
This medicine if taken in combination with alcohol may cause abnormally less blood pressure, and fainting, sweating and dizziness along with it. Hence, alcohol use is recommended to be limited when a person is consuming this medicine.
This medicine interacts with other medicines like Amlodipine, Carbamazepine, Ketoconazole, Phenytoin, Nitroglycerin and Cimetidine. This interaction may harm efficiencies of both medicines.
Pulmonary hypertension mainly occurs due to narrowing of the arteries of the lungs as a result of which the flow of blood is restricted. In this kind of condition, blood fails to carry oxygen to your heart and thus your heart gets adversely affected. The blood pressure of your body will get increased to a great extent if this situation remains untreated, thus leading to bdreadful consequenses, specifically situation like heart failure, serious pulmonary diseases, blood clots in lungs and congenial heart defects, etc.
There are certain forms of pulmonary hypertension, which are serious in nature and worsen with time, so much so that they are even fatal at times. It also includes forms which are non curable in nature, however, in order to improve the quality of life, symptoms can be reduced with proper treatment. The treatment for pulmonary hypertension is often complex and it takes some time to find the most appropriate treatment and requires extensive follow-up care. Your doctor might also need to change your treatment if it's no longer effective. However, when pulmonary hypertension is caused by another condition, your doctor will treat the underlying cause whenever possible.
Common Treatments for pulmonary hypertension:
Erectile dysfunction can be quite a depressing and stressful problem. It can jeopardize the sexual life of a person. In recent times, the problem has been on an exponential rise. As per a survey, 1 in every 1000 men suffers from erectile dysfunction. To top it, some men, out of embarrassment, delay the treatment and medications.
In Erectile Dysfunction, a person is unable to maintain an erection necessary for a sexual intercourse. A man's confidence and self-esteem often take a beating in such cases. In some cases, the affected person completely detaches himself from the outside world. The erectile dysfunction in men can be due to lifestyle habits, psychological problems, injury, and diseases, such as;
Symptoms of erectile dysfunction:
A person with erectile dysfunction may exhibit one or more of the following symptoms:
Diagnosis and Treatment:
As serious as it may appear, there is nothing to press the panic button. The problem is temporary. With timely diagnosis and treatment, erectile dysfunction can be easily managed and treated. Diagnosis of erectile dysfunction include;
A person also needs to
Sildenafil (Viagra), whose function is to inhibit a substance called Phosphodiestarase-5 or PDE5 - was initially used only for the treatment of angina pectoris (a cardiovascular problem) and pulmonary hypertension. Incidentally, it was discovered that it could help the issue of erectile dysfunction too, and thus became hugely popular in the late 1990s. The little blue pill, as it was called, ruled more than 50% of the sexual dysfunction market for more than 15 years. However, as its popularity and usage increased, so did the scientific information about this drug, and now there is an increased speculation that it could be contributing to skin cancer, specifically melanoma. This is considered as one of the most dangerous forms of skin cancer and so the safety of Viagra sildenafil came into question.
Research has shown that users of Viagra sildenafil are at a higher risk for developing melanoma. There are reports stating that about 45 million men are at an increased risk of developing melanoma due to associated Viagra sildenafil use. The risk of developing melanoma was found to increase in men using ED drugs by 21%. Though there is no conclusive proof as yet that sildenafil is the cause, research is increasingly pointing out its role in melanoma. For example, PDE5 inhibitors (sildenafil, tadalafil, vardenafil) are known to promote melanin synthesis, which may exacerbate melanoma development.
The analysis of biochemical pathways of this correlation suggests that Viagra sildenafil triggers a special biochemical action involving the growth-stimulating cGMP (cyclic guanosine monophosphate (an intracellular signaling molecule) which in turn promotes the growth of malignant melanoma. In normal cases, the enzyme phosphodiesterase type 5 (PDE5) regulates the cGMP preventing any adverse cellular activity. Sildenafil inhibits the production of this enzyme, and potentiates a specific cGMP-related biochemical mechanism (called cGMP-cGKI pathway) , and thereby contributes to malignant melanoma. This has been proven to happen in mice and is yet to be proven in humans.
However, there are also reports which suggest that this does not happen due to Viagra sildenafil per se, but due to greater exposure to sun, which even otherwise increases the chances of skin cancer in general, and melanoma in particular. The countering theories also say that the population in which skin cancer was detected, comprised mostly of high income individuals who spent a significant amount of time holidaying on beaches and are not connected to the extensive use of Viagra per se.
Therefore, though there is a correlation that has been established, there is no definite proof that Viagra sildenafil causes skin cancer. It is however, advisable to use ED drugs after medical consultation. If a patient has a genetic predisposition to develop melanoma, it is advisable to seek medical advice before the use of ED drugs. Occasional use should not be harmful. Also, when going out in the sun, limiting exposure to direct sun and UV protection should be managed too. If you wish to discuss any specific problem, you can consult a sexologist.
A bent penis can be a source of genuine concern for a man. Yes, a little curvature in the penis is common, but when the curvature is severe, it can create both physical and emotional problems. Most men with a severely bent penis are considered to have Peyronie's disease, named after the doctor who first described it medically. Since sexual and penis health can be impacted by Peyronie's, it helps to be aware of what treatments are out there for this condition.
In 2016, the World Journal of Men's Health published "Nonsurgical Interventions for Peyronie's Disease: Update as of 2016," an overview of the existing treatments for a bent penis. Following is a distillation of the information contained in that article.
First, a little about Peyronie's disease. The Mayo Clinic describes this disorder as "the development of fibrous scar tissue inside the penis that causes curved, painful erections." This scar tissue usually develops due to injury to the penis. For example, a man might be struck in the penis by a baseball, might slam his erection into a hard surface or might simply experience repeated rough (if pleasurable) handling during sex. Such activities create trauma in the penis; as it heals (even from small traumas like rough handling), scar tissue forms. If that tissue forms repeatedly in one area, it prevents the skin from stretching properly, causing the penis to bend during an erection.
Among the treatment options are:
1. Oral options. A wide range of pills are sometimes used in treating Peyronie's, including vitamin E, tamoxifen, L-carnitine and tadalafil. Such options are typically employed first, as they are the easiest treatment available. Typically, these therapies show results in cases where the scar tissue is less intense. Some of these options are also available for topical application directly on the penis skin.
2. Injections. More persistent cases may respond to the injection of medication directly in the area where the scar tissue build-up is pronounced. As of this writing, only one drug is approved for this method in the U.S. Many men resist this treatment as, understandably, the idea of injecting a needle into the penis does not appeal to them.
3. Traction. Traction therapy essentially works to pull the penis back into shape. A man wears (for several hours each day), a device that attaches to the penis and exerts force to pull it in the opposite direction of the curve. Traction devices tend to work best in conjunction with other therapies rather than on their own.
4. Shock wave therapy. A more recent addition, shock wave therapy uses high amplitude pulses of energy directed at the penis. Typically used on joint and tendon issues, the therapy seems to help with the pain that some experience from Peyronie's but has not yet been shown to make much difference in the curvature.
5. Surgery. There are several surgical approaches to correct the curvature of Peyronie's. Because some cases correct themselves over time, surgery is usually recommended only when the bent penis has been an issue for a year or longer and/or when the physical or emotional distress it causes is significant.
Whatever approach a man may take to treat a bent penis due to Peyronie's disease, he is better positioned if his penis is in good health - and that is more easily obtained when he regularly utilizes a top drawer penis health crème (health professionals recommend Man1 Man Oil, which is clinically proven mild and safe for skin). Some of the best crème contains both vitamin E and L-carnitine, which are sometimes used to help treat Peyronie's. The best crème will also include vitamin D, the "miracle vitamin" that has proven benefits in fighting diseases and supporting healthy cellular function.
Impotence is not a matter of joke. Medically called erectile dysfunction or ED, this condition affects a man’s ability to perform in bed and achieve or maintain an erection, and/or ejaculate. This condition restricts or completely forbids penetrative sex.
Though impotence can occur in men of all ages, its risk increases with age. The common causes of impotence range from the emotional, psychological to the physical like:
The good news is that impotence is a treatable condition. But the challenge is not to take it lightly and ignore it because it can signal serious underlying problems like heart disease and diabetes. It is advisable that a man affected by impotence should consult a doctor immediately, even if he thinks it’s just caused by stress or his current partner. If you wish to discuss about any specific problem, you can consult a Sexologist.