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Overview

Doxoril 400 MG Tablet

Manufacturer :  Macleods Pharmaceuticals Pvt.Ltd
Medicine Composition :  Doxofylline
Prescription vs OTC : Prescription by Doctor required

About Doxoril 400 MG Tablet

This medication is a xanthine derivative drug used in the treatment of asthma and other obstructive diseases. It is a potent bronchodilator and helps relax the smooth muscles of the airway leading to the lung.

This medication is used as a maintenance treatment for wheezing, shortness of breath, chest tightness associated with lung diseases like asthma, chronic bronchitis, emphysema and other diseases related to the respiratory system.

Though a specialized drug there are a few side effects to this drug such as palpation or increase in heartbeat, nausea, dizziness, insomnia and slight headaches. It has anti-tissue and bronchodilator effects and as a phosphodiesterase inhibitor.

This is a relatively safe drug and apart from not having many side effects has a very little interaction with other diseases, even so it is not safe for expecting or breastfeeding mothers.

No habit-forming tendencies are found. The is a newer generation of Xanthine Bronchodilator or in simpler words an inhaler, which does not have major Cardiovascular Adverse effects. Differing from its predecessors it is relatively safer and has fewer drug on drug interaction.

Before using this medication, inform your doctor about your current list of medications, pre-existing diseases, over the counter products, allergies, and current health conditions. Some health conditions may make you more susceptible to the side-effects of the drug.

This medicine is not recommended for use by women who are pregnant or breastfeeding as the risk of adverse effects on the foetus or infant is very high. People suffering from myocardial infarction, peptic ulcers, hyperthyroidism, seizure disorders also should not take this drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the uses of Doxoril 400 MG Tablet

    • Asthma

    • Chronic Obstructive Pulmonary Disorder (Copd)

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the contraindications of Doxoril 400 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the side effects of Doxoril 400 MG Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Key highlights of Doxoril 400 MG Tablet

    • How long is the duration of effect?

      The duration of the effect of Doxoril 400 MG Tablet is not clinically established but is know to last longer than other xanthine derivatives.

    • What is the onset of action?

      The amount of time taken for the onset of action is not clinically established.

    • Are there any pregnancy warnings?

      This drug is not safe for use during pregnancy, unless suggested by the doctor it is not at all recommended to take this medication. Weigh out the pros and cons before you start.

    • Is it habit forming?

      No habit forming tendencies were reported, addiction was not seen.

    • Are there any breast-feeding warnings?

      This medication is not at all recommended for mothers who are breast feeding as it is reported to be fatal for the feeding child. Consult your doctor if you have further queries.

    • Is It safe with alcohol?

      Interaction with alcohol is not know, it is advisable to consult your doctor before you start drinking while under the medication.

    • Is it safe to drive while on this medicine?

      This medication is reported to cause drowsiness in some cases and is hence not recommended while driving.

    • Does this affect kidney function?

      This medication should be used with caution by patients suffering from impaired kidney functions and may require some monitoring and dose adjustment in those cases.

    • Does this affect liver function?

      This medication should be used with caution by patients suffering from impaired liver functions and may require some monitoring and dose adjustment in those cases.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the substitutes for Doxoril 400 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Doxoril 400 MG Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Take the missed dose as soon as you remember. If its almost time for the next schedule dose then the missed one can be skipped.

    • Are there any overdose instructions?

      If incase of an overdose contact your doctor. The symptoms of overdose may include nausea, vomiting, restlessness , insomnia and increase in heart rate.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    Where is the Doxoril 400 MG Tablet approved?

    • India

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

    How does this medication work?

    This medication works by competitively blocking the action of certain enzymes that are responsible for smooth muscle contractions in the lungs.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Pulmonologist before using this medicine.

      What are the interactions of Doxoril 400 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Contrary to its predecessor it does not have many interaction with drugs, however some drugs should be avoided like Allopurinol, Phenytoin, Propranolol and Cimetidine to avoid certain allergic reaction.
      • Interaction with Food

        You should limit your intake of caffeine as it may alter the functioning of the drug.

      • Interaction with Disease

        Though there are lesser disease-drug interaction compared to other xanthine derivatives, people with these diseases should be careful. Peptic ulcer, seizure disorders, heart rhythm disorder and hyperthyroidism.

      FAQs about Doxoril 400 MG Tablet

      • Ques : What is Doxoril 400 MG Tablet?

        Ans : Doxoril 400 MG Tablet is a medicine used in Asthma. Doxofylline tablet is used to control Wheezing and Chest tightness. This medication is prescribed to patients having conditions like shortness of breath and severe coughing.

      • Ques : What is the use of Doxoril 400 MG Tablet?

        Ans : Doxoril 400 MG Tablet is used for the treatment of conditions like Chronic Asthma and obstructive diseases. It is also used to control Lung diseases. Doxofylline helps to improve breath shortness and emphysema. This medicine prevents Chronic bronchitis and chest tightness.

      • Ques : What are the side effects of Doxoril 400 MG Tablet?

        Ans : Doxoril 400 MG Tablet has many common side effects such as Headache and increased heartbeat. There are some serious side effects of this medicine like increase in blood sugar, Vomiting and Nausea. In case of patients, having any of the side effects or issues like Muscle weakness and dizziness. It is advised to stop the consumption of Doxofylline and contact to doctor as soon as possible.

      • Ques : For what treatment Doxoril 400 MG Tablet used for?

        Ans : Doxoril 400 MG Tablet is used to treat conditions like Chest tightness and chronic bronchitis. It is also used to control obstructive diseases. Doxofylline helps to improve asthma and breathing problems. This medicine also helps to prevent Wheezing and emphysema.

      • Ques : How long do I need to use Doxoril 400 MG Tablet before I see improvement in my condition?

        Ans : This medication should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor. Also taking this medication longer than it was prescribed, can cause an inadequate effect on the patient's condition. So please consult your doctor.

      • Ques : At what frequency do I need to use Doxoril 400 MG Tablet?

        Ans : The duration of effect for this medicine is dependent on the severity of the patient’s condition. Therefore the frequency of usage of this medication will vary from person to person. It is advised to follow the proper prescription of the doctor, directed according to the patient's condition.

      • Ques : Should I use Doxoril 400 MG Tablet empty stomach, before food or after food?

        Ans : This medication is advised to be consumed orally. The salts involved in this medication react properly if it is taken after having food. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it.

      • Ques : What are the instructions for the storage and disposal of Doxoril 400 MG Tablet?

        Ans : This medication contains salts which are suitable to store only at room temperature, as keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      References

      • Doxofylline-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 3 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/doxofylline

      • Doxofylline-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 3 June 2022].Available from:

        https://go.drugbank.com/drugs/DB09273

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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