Covishield was created by the Central Drug Standard Control Organization (CDSCO) and later its production was taken over by the SII (Serum Institute of India). The vaccine was a recombinant version of the Oxford-AstraZeneca covid vaccine.
As per the guidelines set by the Indian Government and Drug Controller General of India (DCGI), the vaccine is approved to use in emergency cases among 18 and above receivers. The key element in Covishield was the replication-deficient chimpanzee adenovirus vector encoded with SARS-CoV-2 Spike (S) glycoprotein.
Produced in genetically modified human embryonic kidney (HEK) 293 cells which are recombinant with-
- ChAdOx1 nCoV- 19 CoronaVirus Vaccine (Recombinant) 5 × 10viral particles (vp)
- genetically modified organisms (GMOs)
- L-Histidine and L-Histidine hydrochloride monohydrate
- Magnesium chloride hexahydrate
- Polysorbate 80
- Disodium edetate dihydrate (EDTA)
- Sodium chloride
Intramuscular and subcutaneous vaccines like Covishield need to be administered in the thickest portion of the center of the deltoid muscle. These kinds of muscles are mostly located in the upper arm in adults and upper thigh in infants.
The Vaccine course of Covishield consists of two separate doses of 0.5 ml each which is recommended to be taken in the gap of 4 to 6 weeks.
As per the data available from the outgoing vaccine research, the administration gap between the two can be extended up to 12 weeks. The receiver doesn't have to repeat the 1st dose even if the gap between the two jabs is more than 12 weeks.
As per the data provided by the government of India, Covishield has shown approximately 70%- 100% efficacy against coronavirus within 14 days of a complete course. The complete course comprises 2 doses that need to be administered in the gap of 4 weeks.
Depending upon your immunity system, side effects may last up to 2-3 days. These symptoms may rarely extend their duration up to 5 - 7 days. It is advised to avoid the second dose of the vaccine if one experiences these symptoms within 14 to 33 days of administration. Some of the side effects triggered from Covishield can be seen within 6 to 8 hrs of receiving the first dose of vaccine.
Other than the common reactions, studies have shown some out of the ordinary symptoms after first does of COVISHIELD vaccine, some of them are - Abdominal pain, Sleepiness or feeling dizzy, Enlarged lymph nodes, Excessive sweating, Itchy skin, Rash or hives, Severe allergic reaction (anaphylaxis), Confusion or seizures (fits), Blurred vision, Leg swelling and pain, Unusual skin bruising around the site of vaccination, Shortness of breath and Chest pain.
Furthermore, there are certain repercussions of the vaccines that are rare amongst receivers but can be life-threatening, like major blood clotting (cerebral venous sinus/splanchnic vein or arterial thrombosis) followed by low platelet count (thrombocytopenia) and severe allergic reaction. If one suspects any of the symptoms associated with these conditions, they must seek immediate medical attention as it can be fatal.
This drug can be used in below-mentioned conditions
Are there any pregnancy warnings?
This vaccine is found to be safe to be used in pregnant women. Clinical studies are still under process and there could be any unforeseen effect on the fetus which is yet to be identified.
Are there any breast-feeding warnings?
This vaccine is still under clinical trial and for now its effect is unknown in nursing women.
Is It safe with alcohol?
It is advised to avoid alcohol consumption for a brief period of time before getting vaccinated, as it might affect people’s immune responses to the jab.
Is it safe to drive while on this medicine?
This vaccine is not found to affect people's consciousness. If you feel dizzy, then you must avoid driving.
Does this affect kidney function?
Vaccine is safe to be administered to the patient with kidney disease of any severity.
This vaccine has been demonstrated to cause or worsen chronic liver diseases.
Below is the list of medicines, which contains Covishield as ingredient
COVISHIELD is a monovalent vaccine composed of a single recombinant, replication-deficient chimpanzee adenovirus (ChAdOx1) vector encoding the S glycoprotein of SARS-CoV-2. After its administration, the S glycoprotein of SARS-CoV-2 is expressed locally stimulating neutralizing antibody and cellular immune responses.
Ques: What is the common name for Covishield COVID-19 Vaccine?
Ques: What are the uses of the Covishield?
Ques: How long do I need to use Covishield before I see improvement in my condition?
Ques: At what frequency do I need to use Covishield?
Ques: Should I use Covishield empty stomach, before food or after food?
Ques: What are the instructions for the storage and disposal of Covishield?
Ques: Is there any difference between 1st and 2nd doses of Covishield?
Ques: Do I require any test pre or post getting Covishield?
Ques: What are the drawbacks for receiving the Covishield vaccine?
Ques: When should I expect any side effects reactions to Covishield?
- Joint pain or muscle ache
- Fever and chills
- Sore throat and runny nose
- Abdominal pain
- rash, Itchy skin, or hives
- Enlarged lymph nodes
- Excessive sweating
Ques: Can you consume smoke/alcohol after getting vaccinated with Covishield?
Ques: Can women who are pregnant, breastfeeding, or having maturation receive Covishield?
Ques: Can a person mix the first dose of AstraZeneca's vaccine with the second dose of Covishield or any other vaccine dose in India?
Ques: Can one take Covishield between the course of Birth control?
Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.
Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.