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Bromocriptine

Prescription vs.OTC: Prescription by Doctor required

Bromocriptine is used in the treatment of Parkinson’s disease. It can control symptoms of hyperprolactinemia including excess production of breastmilk, hypogonadism, infertility and a number of disruptions in the menstrual cycle. The drug helps to control the abnormally high production of growth hormones, and can inhibit the growth of certain tumours that release excess amounts of prolactin.

Bromocriptine has strong dopaminergic effects and works by activating dopamine D2 receptors and also as a partial agonist of D1 receptors. Postsynaptic activation of D2 receptors lead to antiparkinson effects whereas presynaptic activation of D2 receptors lead to neuroprotective effects. Activation of D2 receptors in the nigrostriatal pathway is responsible for improving coordinated muscle movements in people with Parkinson’s. Bromocriptine also has prolactin inhibitory effect by inhibiting lactotrophic cells in the anterior pituitary from secreting prolactin due to increased production of dopamine.

Bromocriptine may cause some side effects including nausea, light-headedness, dizziness, drowsiness, vomiting, irregular heartbeat, hypotension, vasospasms, insomnia, depression and fatigue. Consult your doctor immediately if you experience any of the more serious side effects like fainting, hallucinations, mental or mood changes like anxiety, paranoia, or confusion, swollen feet or ankles, vomit containing blood or particles which look like coffee grounds, impaired vision, chest pain, abnormal coloured stool, breathing problems, numbness on one side of body and a persistent runny nose.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Endocrinologist before using this medicine.

female infertility
type 2 diabetes
In addition to its intended effect, Bromocriptine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Is It safe with alcohol?
D-bro 2.5mg tablet may cause excessive drowsiness and calmness with alcohol.
Are there any pregnancy warnings?
D-bro 2.5mg tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Are there any breast-feeding warnings?
D-bro 2.5mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
Is it safe to drive while on this medicine?
Caution is advised when driving or operating machinery.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which contains Bromocriptine as ingredient
Hi Tech Pharmaceuticals Pvt Ltd
Serum Institute Of India Ltd
Delvin Formulations Pvt Ltd
Helios Pharmaceuticals
Helios Pharmaceuticals
Inga Laboratories Pvt Ltd
Serum Institute Of India Ltd
Zyphar s Pharmaceuticals Pvt Ltd
Ar-Ex Laboratories Pvt Ltd
Inga Laboratories Pvt Ltd
Serum Institute Of India Ltd
Ar-Ex Laboratories Pvt Ltd
Sanzyme Ltd
Serum Institute Of India Ltd
Serum Institute Of India Ltd
Zyphar s Pharmaceuticals Pvt Ltd
Delvin Formulations Pvt Ltd
Serum Institute Of India Ltd
Glaxo SmithKline Pharmaceuticals Ltd
Micro Labs Ltd
Bromocriptine is an ergot derivative that works as a dopamine D2 agonist. It exhibits antiparkinson and lactation inhibiting effect by selectively binding to dopamine D2 receptors in the CNS. This inhibits adenylyl cyclase which prevents signal transduction mediated via cAMP and results in an inhibition of neurotransmission.
What are you using Bromocriptine for?
Other
female infertility
type 2 diabetes
How much was the improvement?
Average
How long did it take before seeing improvement?
Within 2 hours
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am using bromergon pills or I think it is Bromocriptine in english for my Hyperprolactinemia. Can I use zeolit when I am drinking my pills?

MD - Obstetrtics & Gynaecology, FCPS, DGO, Diploma of the Faculty of Family Planning (DFFP)
Gynaecologist, Mumbai
I am using bromergon pills or I think it is Bromocriptine in english for my Hyperprolactinemia. Can I use zeolit when...
any drug can be prescribed with details required by only doctor who has examined you or can examine you so go to such medical practitioner.

I am 31 year old female. After my delivery i.e.on 21 may 2011 I had excessive bleeding on the very next day and after 40 days of my delivery I have irregular periods till date so that I have undergone prolactin test. According to the reports there is decreased levels of pituitary necrosis, bromocriptine administration, pseudohypoparathyroidism. Test reading is prolactin serum 1.82ng/ml. Please explain the report to me. Is there anything serious? Kindly help me out.

DHMS (Hons.)
Homeopath, Patna
I am 31 year old female. After my delivery i.e.on 21 may 2011 I had excessive bleeding on the very next day and after...
Hello, menstrual disorder is caused due to stress, anxiety, depression, malnutrition, anaemia, over exertion, pcod, causes, delayed, painful, excess & frequent blood flow during menstruation. * tk, plenty of water to hydrate yourself, to eliminate toxins & to dilute your blood to ease your problem. * go for meditation to reduce your stress, anxiety to calm your nerve to ease your stress. * your diet be simple, non- irritant, easily digestible on time to maintain your digestion. * tk, apple, carrots, cheese, milk, banana, papaya, spinach, almonds, walnuts to improve your haemoglobin to release your flow. * tk, homoeo medicne, gentle & rapid in action with no adverse effect, thereof. @ pulsatilla 20-6 pills, thrice a day. @ sepia200-6 pills, thrice a day. * ensure, sound sleep in d night for at least 7 hrs. * avoid, caffiene, junkfood, dust, smoke, exertion. Tk, carethe.

My mother 63 years is suffering from parkinson (PD) since 2013 is on syndopaplus (7 am&12 pm) and syndopa (3 pm) medication 3 times a day when syndopa withdraws thereby inducing stiffness & rigidity resulting in seizure thereby finding very hard to move and not even able to getup from bed or chair without assistance. Neurologist has now prescribed Bromocriptine 2.5 mg along with syndopa (twice 7 am & 7 pm) to mitigate syndopa side effect. Can this be taken at 7 am and 3 pm instead of 7 pm as the last syndopa taken is at 3 pm or any other alternatives suggestions is welcome.

Observer Cum Fellowship, Certificate in Forensic Psychology, MD-Psychiatry, MBBS
Psychiatrist, Akola
My mother 63 years is suffering from parkinson (PD) since 2013 is on syndopaplus (7 am&12 pm) and syndopa (3 pm) medi...
Simple answer is No. Syndopa has very short effective concentration in blood & hence as soon as it's blood levels begin to decrease, thereby decreasing it's brain levels, your mother starts getting movement related difficulties If you feel she is not getting optimal treatment, discuss with your doctor about other effective medicines like Ropinirole, pramirole etc to increase efficiency of Syndopa combination. But don't change time of medication administration.
1 person found this helpful

Popular Health Tips

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Diabetes Management in Ramadan

During Ramadan, diabetics who chose to fast should be educated about how to adjust their medications and be prepared to break the fast if necessary.
During the lunar-based month of Ramadan, Muslims abstain from eating, drinking, smoking, or using oral medications from predawn to sunset.
Followers will typically eat just after sunset and again before dawn.
In general, fasting is not recommended for people with diabetes. The practice increases the risk for both hypoglycemia from lack of food and hyperglycemia resulting from cutting back too far on medication in attempts to avoid hypoglycemia. Hyperglycemia can also occur if patients overeat after sundown.
If the period of fasting is longer and the two meals are eaten close together, this can be tricky.
Islamic law does not require fasting when it would create a physical danger.
Fasting is especially risky for those with type 1 diabetes, for pregnant women, and for children. However, patients with well-controlled type 1 diabetes who use insulin pumps can often accomplish fasting by adjusting their basal infusion rates and monitoring their blood glucose levels frequently.
For patients with type 2 diabetes taking medications other than insulin or sulfonylureas, the risk for hypoglycemia is low. However, because of the prohibition against taking oral medication during daylight hours, patients who usually take metformin 3 times daily should take two-thirds of the dose at the sunset meal and one-third at the predawn meal.
Long-acting sulfonylureas should be avoided.
Once-daily sulfonylureas should be taken at the sunset meal.
For patients taking twice-daily sulfonylureas, the usual dose should be taken at the evening meal and half the usual dose before the predawn meal. One can also skip the predawn dose altogether.
The very short-acting insulin secretagogues repaglinide or nateglinide can be taken before each of the meals.
No adjustments are needed for thiazolidinediones, alpha-glucosidase inhibitors, incretin-based therapies, or bromocriptine.
Basal insulin doses should be reduced by about 30% to 40%. Patients who are on either mixed or intermediate-acting insulins should switch to basal insulin.
The usual dose of rapid-acting insulin should be taken before the sunset meal. The predawn dose of rapid-acting insulin can be cut to half or omitted.
Frequent monitoring is the key. Patients should be advised to break their fast if the blood sugar drops below 70 mg/dL. If it rises above 250 mg/dL ? particularly for patients with type 1 diabetes ? they should also break their fast and take insulin.
Patients should be cautioned against overeating after breaking the fast.
Moderation is the trick. Don't overfill an empty stomach.
Patients should be counseled about avoiding dehydration as much as possible.
Also adjust BP medicines during Ramadan

4 Causes Of Infertility In Females

MBBS, MD - Obstetrtics & Gynaecology, PhD(breast diseases)
Gynaecologist, Chandigarh
4 Causes Of Infertility In Females

Infertility is a condition wherein a woman does not get pregnant in spite of having unprotected sexual intercourse over a period of a year or even more. An abnormal menstrual cycle that is either too short or too long, irregular or even scanty can be an indication of a lack of ovulation, which in turn, is another factor behind female infertility.

Causes-

  1. Ovulation disorders are characterized by either a lack of ovulation or irregular and infrequent ovulation. These are a major cause of infertility. This may be due to defects in the regulation of the reproductive hormones by the pituitary gland or the hypothalamus (brain center responsible for producing some of the most essential hormones required by the body). Malfunctioning of the ovary is another cause in itself. Polycystic Ovarian Syndrome, premature failure of the ovaries (a condition wherein a woman’s ovaries fail to function properly even before she is 40 years old), hypothalamic dysfunction (a dysfunction of the hypothalamus) and excessive production of prolactin (a hormone that stimulates milk production among women after childbirth) by the pituitary gland are some of the factors responsible for the occurrence of such a disorder.

  2. Damaged fallopian tubes do not allow the sperms to fuse properly with the egg. They might also prevent the fertilized egg from entering into the uterus. This condition may be caused due to pelvic inflammatory diseases (a group of infections of the reproductive organs in women), an infection in the fallopian tubes or the uterus caused due to various Sexually Transmitted Diseases, any abdominal surgery or surgery of the pelvic region and pelvic tuberculosis.

  3. Endometriosis, wherein the tissue that usually grows in the uterus, starts growing outside it, is another factor responsible for infertility.

  4. Several cervical or uterine disorders, such as tumors, inflammation within the uterus, uterine abnormalities, a cervical narrowing or the inability of the cervix to produce mucous for the sperm to travel to the uterus, are likely to impact fertility by obstructing implantation or enhancing the chances of miscarriage.

Treatments-

  1. Fertility drugs can be used to regulate and induce ovulation. But they carry with them certain risks and therefore you should consult your physician prior to consumption. Few examples of these drugs are Clomiphene Citrate, Gonadotropins, Metformin, Letrozole and Bromocriptine.

  2. Surgical procedures can be recommended to correct reproductive abnormalities and restore fertility. A laparoscopic surgery or a tubal ligation reversal surgery (a surgery that unites one’s fallopian tubes again in order to enable the woman to have a baby) can be advised by the doctor.

  3. Reproductive assistance by Intrauterine insemination (a process that involves putting sperms inside a woman’s uterus in order to help her conceive) and Assisted reproductive technology (consisting of IVF and surrogacy). Consult an Expert & get answers to your questions!
5089 people found this helpful

Female Infertility - 2 Treatment Procedures

Royal College of Obstetricians and Gynaecologists (MRCOG)
Gynaecologist, Alwar
Female Infertility - 2 Treatment Procedures

Infertility is a condition wherein a woman does not get pregnant in spite of having unprotected sexual intercourse over a period of a year or even more. An abnormal menstrual cycle that is either too short or too long, irregular or even scanty can be an indication of a lack of ovulation, which in turn, is another factor behind female infertility.

Causes-

  1. Ovulation disorders are characterized by either a lack of ovulation or irregular and infrequent ovulation. These are a major cause of infertility. This may be due to defects in the regulation of the reproductive hormones by the pituitary gland or the hypothalamus (brain center responsible for producing some of the most essential hormones required by the body). Malfunctioning of the ovary is another cause in itself. Polycystic Ovarian Syndrome, premature failure of the ovaries (a condition wherein a woman’s ovaries fail to function properly even before she is 40 years old), hypothalamic dysfunction (a dysfunction of the hypothalamus) and excessive production of prolactin (a hormone that stimulates milk production among women after childbirth) by the pituitary gland are some of the factors responsible for the occurrence of such a disorder.

  2. Damaged fallopian tubes do not allow the sperms to fuse properly with the egg. They might also prevent the fertilized egg from entering into the uterus. This condition may be caused due to pelvic inflammatory diseases (a group of infections of the reproductive organs in women), an infection in the fallopian tubes or the uterus caused due to various Sexually Transmitted Diseases, any abdominal surgery or surgery of the pelvic region and pelvic tuberculosis.

  3. Endometriosis, wherein the tissue that usually grows in the uterus, starts growing outside it, is another factor responsible for infertility.

  4. Several cervical or uterine disorders, such as tumors, inflammation within the uterus, uterine abnormalities, a cervical narrowing or the inability of the cervix to produce mucous for the sperm to travel to the uterus, are likely to impact fertility by obstructing implantation or enhancing the chances of miscarriage.

Treatments-

  1. Reproductive assistance by Intrauterine insemination (a process that involves putting sperms inside a woman’s uterus in order to help her conceive) and Assisted reproductive technology consisting of IVF, which is the safest and the best.

  2. Fertility drugs can be used to regulate and induce ovulation. But they carry with them certain risks and therefore you should consult your physician prior to consumption. Few examples of these drugs are Clomiphene Citrate, Gonadotropins, Metformin, Letrozole and Bromocriptine.

  3. Surgical procedures can be recommended to correct reproductive abnormalities and restore fertility. A laparoscopic surgery or a tubal ligation reversal surgery (a surgery that unites one’s fallopian tubes again in order to enable the woman to have a baby) can be advised by the doctor.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5634 people found this helpful

MD-PhD, FIPS, Fellow of Academy of General Education (FAGE), DPM, MBBS
Psychiatrist, Jalandhar
Cocaine Detoxification

Medical Detoxification is a process that systematically and safely withdraws people from addicting drugs, usually under the care of a physician. Drinking alcohol or using drugs can cause physical dependence over time and stopping them can result in withdrawal symptoms in people with this dependence. The detoxification process is designed to treat the immediate bodily effects of stopping drug use and to remove toxins left in the body as a result of the chemicals found in drugs and/or alcohol.

While at the present time, no proven pharmacologic therapy for cocaine addiction exists, several kinds of medications have been used in the detoxification of cocaine. Withdrawal from chronic cocaine use produces anxiety, depression and intense cravings for the drug. Several types of medications address these issues in different ways.

Antidepressant drugs such as desipramine or a combination of phentermine and fenfluramine have been used to reduce cocaine withdrawal symptoms such as anxiety and depression. Benzodiazepines, tranquilizers such as Diazepam, have been used to reverse anxiety induced by cocaine withdrawal. Amantadine, a drug used to treat Parkinson's Disease, may be an effective treatment for cocaine-dependent patients with severe cocaine withdrawal symptoms and may reduce cocaine craving. Bromocriptine, a drug that works on the brain's dopamine system, has been used to decrease the craving for cocaine during detoxification and to reduce mood disturbance.

Propanolol, a beta-blocker drug used to treat high blood pressure, may be useful for severe cocaine withdrawal symptoms, as it slows down the effects of adrenaline, thereby calming the body's "fight or flight" response to stressful situations. This type of drug has been used to treat general anxiety and anxiety associated with alcohol withdrawal. Propranolol's lessening of symptoms such as palpitations and sweating has helped reduce cocaine craving. Its use, however, is not risk free in patients who have taken cocaine and can be associated with decreased blood flow to the heart and other changes that predispose patients to arrhythmia and a severe increase in blood pressure that can lead to a stroke. Delayed toxic effects are possible. Any use of beta-blockers in this setting requires careful monitoring and caution
1 person found this helpful

Infertility - 4 Causes Behind It

MD - Obstetrtics & Gynaecology, MBBS, DGO
Gynaecologist, Mumbai
Infertility - 4 Causes Behind It

Infertility is a condition wherein a woman does not get pregnant in spite of having unprotected intercourse over a period of a year or even more. An abnormal menstrual cycle that is either too short or too long, irregular or even scanty can be an indication of a lack of ovulation, which in turn, is another factor behind female infertility.

Causes

  1. Ovulation disorders are characterized by either a lack of ovulation or irregular and infrequent ovulation. These are a major cause of infertility. This may be due to defects in the regulation of the reproductive hormones by the pituitary gland or the hypothalamus (brain center responsible for producing some of the most essential hormones required by the body). Malfunctioning of the ovary is another cause in itself. Polycystic Ovarian Syndrome, premature failure of the ovaries (a condition wherein a woman’s ovaries fail to function properly even before she is 40 years old), hypothalamic dysfunction (a dysfunction of the hypothalamus) and excessive production of prolactin (a hormone that stimulates milk production among women after childbirth) by the pituitary gland are some of the factors responsible for the occurrence of such a disorder.

  2. Damaged fallopian tubes do not allow the sperms to fuse properly with the egg. They might also prevent the fertilized egg from entering into the uterus. This condition may be caused due to pelvic inflammatory diseases (a group of infections of the reproductive organs in women), an infection in the fallopian tubes or the uterus caused due to various Sexually Transmitted Diseases, any abdominal surgery or surgery of the pelvic region and pelvic tuberculosis.

  3. Endometriosis, wherein the tissue that usually grows in the uterus, starts growing outside it, is another factor responsible for infertility.

  4. Several cervical or uterine disorders, such as tumors, inflammation within the uterus, uterine abnormalities, a cervical narrowing or the inability of the cervix to produce mucous for the sperm to travel to the uterus, are likely to impact fertility by obstructing implantation or enhancing the chances of miscarriage.

Treatments

Fertility drugs can be used to regulate and induce ovulation. But they carry with them certain risks and therefore you should consult your physician prior to consumption. Few examples of these drugs are Clomiphene Citrate, Gonadotropins, Metformin, Letrozole and Bromocriptine.

  1. Surgical procedures can be recommended to correct reproductive abnormalities and restore fertility. A laparoscopic surgery or a tubal ligation reversal surgery (a surgery that unites one’s fallopian tubes again in order to enable the woman to have a baby) can be advised by the doctor.

  2. Reproductive assistance by Intrauterine insemination (a process that involves putting sperms inside a woman’s uterus in order to help her conceive) and Assisted reproductive technology (consisting of IVF and surrogacy).
5207 people found this helpful

Table of Content

About Bromocriptine
When is Bromocriptine prescribed?
What are the side effects of Bromocriptine ?
Key highlights of Bromocriptine
Medicines containing Bromocriptine
How does medicine works?