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Overview

Brinzolamide

Prescription vs OTC : Prescription by Doctor required

About Brinzolamide

Brinzolamide is commonly available in the form of a solution, to be administered as eye drops. It is mainly used to reduce elevated levels of pressure in the eye, especially in patients suffering from ocular hypertension and / or open-angle glaucoma.

This medication acts as an inhibitor of carbonic anhydrase, which causes an increase in the amount of fluid to be present in the eye. Hence, this medicine works by reducing the amount of fluid present in the eye, which further leads to a reduction in ocular pressure.

Consult your doctor if you wear contact lenses. The chances of this medicine being absorbed into your bloodstream are very low, almost negligible. Therefore the probability of any drug interactions with this medicine is very low.

You are strongly recommended to avoid using these eye drops if you have had an allergic reaction to any of the ingredients in this medicine.

The drops may cause a brief stinging or burning sensation in the eyes, which is quite normal, but if this persists, consult with your medical practitioner. This medication may cause blurred vision, therefore, do not drive in such cases.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    What are the uses of Brinzolamide

    • Glaucoma

    • Increased Intraocular Pressure

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    What are the contraindications of Brinzolamide ?

    • Hypersensitivity

    • Kidney Impairment

    • Metabolic Acidosis

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    What are the side effects of Brinzolamide ?

    • Stinging In The Eyes

    • Blurred Vision

    • Burning Eyes

    • Eye Irritation

    • Eye Pain

    • Altered Taste

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    Key highlights of Brinzolamide

    • Is It safe with alcohol?

      No interaction found

    • Are there any pregnancy warnings?

      This medication may be unsafe to use during pregnancy.
      Animal studies have shown adverse effects on the fetus, however, there are limited human studies.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      Patient should wait until the vision clears before driving or using machines.

    • Does this affect kidney function?

      Caution to be advised in patients with impaired renal function.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    • What is the onset of action?

      The effect is initiated within 30 minutes after its administration.

    • How long is the duration of effect?

      The medication remain active for about 8 - 12 hrs after its administration.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medication, please consult your doctor.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    Medicines containing Brinzolamide

    Below is the list of medicines, which contains Brinzolamide as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

    How does this medication work?

    This medication belongs to Carbonic Anhydrase II (CA) inhibitor class. It is a highly specific, non-competitive and reversible type of inhibitor in nature. CA inhibition in the eyes slows down bicarbonate formation and reduces transport of sodium and fluids, which reduces aqueous humour secretion and intraocular pressure.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Ophthalmologist before using this medicine.

      What are the interactions of Brinzolamide ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medicine interacts with the following medicine ketoconazole, itraconazole, clotrimazole, ritonavir and troleandomycin

      FAQs about Brinzolamide

      • Ques : What is Brinzolamide?

        Ans : This medication is commonly available in the form of a solution, to be administered as eye drops.

      • Ques : How long do I need to use Brinzolamide before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Brinzolamide?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Brinzolamide empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Brinzolamide?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Brinzolamide- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 12 December 2019]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/brinzolamide

      • Brinzolamide- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 12 December 2019]. Available from:

        https://www.drugbank.ca/drugs/DB01194

      • Azopt eye drops, suspension- EMC [Internet] medicines.org.uk. 2018 [Cited 12 December 2019]. Available from:

        https://www.medicines.org.uk/emc/product/3819/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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