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Overview

Domadol Plus 325 Mg/37.5 Mg Tablet

Manufacturer :  Unichem Laboratories Ltd
Medicine Composition :  Paracetamol, Tramadol
Prescription vs OTC : Prescription by Doctor not required

About Domadol Plus 325 Mg/37.5 Mg Tablet

Domadol Plus 325 Mg/37.5 Mg Tablet is used a pain-relieving medication. It is primarily used to treat acute pain. The conditions of acute pain include backache, headache, arthritis and toothache, etc.

This medication is a combination of paracetamol and tramadol. These drugs fall under the class of analgesics, belonging to the category of NSAID and opioid agonist, respectively. This medication also reduces pain in the body caused due to fever.

You should not consume this tablet if:

  • You are allergic to this medicine.
  • You are suffering from a serious liver disorder.
  • You normally consume more than 3 alcohol beverages per day or have a history of alcoholism.

You must not take the medicine in more than the amount prescribed or longer than the prescribed period. It can be taken with food or without it, but you must take it, in the same way, every day.

The medicine must be swallowed whole, without trying to crush, break or mixing it in water. As it is a pain reliever, it is unlikely that you will miss a dose. In case you do, refrain from taking two doses together to make up for the missed one.

    What are the uses of Domadol Plus 325 Mg/37.5 Mg Tablet

    • Acute Pain

    What are the contraindications of Domadol Plus 325 Mg/37.5 Mg Tablet ?

    What are the side effects of Domadol Plus 325 Mg/37.5 Mg Tablet ?

    Key highlights of Domadol Plus 325 Mg/37.5 Mg Tablet

    • How long is the duration of effect?

      The effect lasts for an average of 4-6 hours.

    • What is the onset of action?

      The effect of this medication can be observed within an hour of oral administration. When given in the form of an intravenous injection, the pain-relieving action starts in 5-10 minutes. For fever reduction, the time taken is about 30 minutes.

    • Are there any pregnancy warnings?

      This medication can be given to the women who are breastfeeding but only after evaluating the benefits and risks with the doctor. Report any incidence of rashes on skin or diarrhea in the infant.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medication is safe to use during breastfeeding. It is advised to consult your doctor before taking this medicine. Any incidence of rashes on skin or diarrhea in the infant should be reported.

    What are the substitutes for Domadol Plus 325 Mg/37.5 Mg Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Domadol Plus 325 Mg/37.5 Mg Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Missed Dose instructions

      This medication is usually taken as and when required. If the medicine is taken on a regular basis, then the missed dose should be taken as soon as possible. You should not take the missed dose if it is time for taking the next scheduled dose.

    • Are there any overdose instructions?

      This medication overdosage could cause harmful effects to the body.

    How does this medication work?

    This medication is a combination of Paracetamol and Tramadol. Both the drugs fall under the class of analgesic. Thus medications produce its action following two different paths of the mechanism of action.

    Firstly, it selectively inhibits enzyme function in the brain which allows it to treat pain and fever. It activates certain receptors in the brain that inhibit pain signals.

    Secondly, it acts on certain specific pain receptors in the brain and inhibits the reuptake of norepinephrine, serotonin. It also enhances the release of serotonin thereby changing the perception and response to pain.

      FAQs about Domadol Plus 325 Mg/37.5 Mg Tablet

      • Ques : What is Domadol Plus 325 Mg/37.5 Mg Tablet?

        Ans : This medication has Tremadol and paracetamol as active elements present. It performs its action by obstructing the release of pain and inflammation-causing chemical messengers in the body.

      • Ques : What are the uses of Domadol Plus 325 Mg/37.5 Mg Tablet?

        Ans : This medication is used for the treatment and prevention from conditions such as acute pain, thrombophlebitis, primary dysmenorrhea, joint pain, arthralgia, menstrual pain, osteoarthritis, rheumatoid arthritis and ear pain.

      • Ques : What are the Side Effects of Domadol Plus 325 Mg/37.5 Mg Tablet?

        Ans : This medication has some commonly reported side effects. Here are some side effects of This medication which are as follows: nausea or vomiting, allergic skin reaction, gastric ulcer, fatigue, stomach discomfort, and cramps, dizziness, breathing troubles, and abnormal blood counts.

      • Ques : What are the instructions for storage and disposal Domadol Plus 325 Mg/37.5 Mg Tablet?

        Ans : This medication should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.

      References

      • Acetaminophen- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 10 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/paracetamol

      • Acetaminophen- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 10 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB00316

      • Tramadol- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2020 [Cited 10 February 2020]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/tramadol

      • Tramadol- DrugBank [Internet]. Drugbank.ca. 2005 [Cited 10 February 2020]. Available from:

        https://www.drugbank.ca/drugs/DB00193

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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