Hello, It is advisable to not use too many products on your skin as you are not sure how they will interact with each other on skin. Even if you wash your face, some of the medicine still remains. Instead of a tincture, use Berberis aqui cream on face before sleeping at night for 15 days. Other than that, applying COCONUT WATER on the skin has also proven to be good in reducing pigmentation. Do let me know if this was helpful.