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Sim 5 MG Tablet

Manufacturer: Orchid Chemicals & Pharmaceuticals Ltd
Medicine composition: Simvastatin
Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Sim 5 MG Tablet is present in a cluster of drugs known as ‘statins’. It helps in reducing levels of triglycerides and LDL, also referred to as ‘bad cholesterol’ in the blood and increasing the concentration of HDL (High Density lipoprotein, also called ‘good cholesterol’). Other complications of a heart attack, stroke and associated risk factors can be mitigated in people who suffer from diabetes or other coronary disorders. This drug can be used in case of adults as well as children (who should at least be 10 years old).

Though rare, intake of Sim 5 MG Tablet can damage the muscle tissues of the skeletal system, thus causing kidney failure. Seek timely medical attention if you happen to experience tenderness, muscle pain or weakness accompanied by a fever, unusual fatigue and urine that’s dark in color.

The risk factors of taking this medicine include whether you have suffered from any kidney or liver disorders in the past or presently suffer from lifestyle disorders such as diabetes, thyroid afflictions or have a drinking habit of more than 2-3 pegs daily. Pregnant women are advised against using Sim 5 MG Tablet.

Keep in mind that consuming grape juice or the fruit as a whole prior to or right after taking this drug can cause dangerous complications. Your doctor might have to alter the entire treatment schedule if you have been taking antibiotics, medications for Hepatitis C, heart diseases, HIV/AIDS or any other antifungal drugs.

The most common side effects associated with Sim 5 MG Tablet are dizziness, irregular heartbeats and episodes of fainting. Lesser known adverse reactions may include bladder pain, cough, chills, blurred vision, body pain, dry mouth, breathing difficulties, painful urination, fever, dry skin, increased thirst and appetite, pain in the joints and sore throat.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

  • Hyperlipidemia

    Sim 5 MG Tablet is used to treat Hyperlipidemia, which is a condition characterized by high levels of lipids in the blood.
  • Homozygous Familial Hypercholesterolemia

    Sim 5 MG Tablet is used in the treatment of Homozygous Familial Hypercholesterolemia which is a genetic disorder characterized by high cholesterol levels.
  • Prevention Of Cardiovascular Diseases

    Sim 5 MG Tablet is used to reduce the incidence of heart attacks by reducing the levels of bad cholesterol in the body.
  • Allergy

    Avoid taking this medicine if you have a known history of allergy to it.
  • Impaired Liver Function

    Avoid taking this medicine if you are suffering from a liver disease or if there is any abnormality in the liver function tests.
  • Dizziness

  • Fast Heartbeat

  • Dark Colored Urine

  • Muscle Or Joint Pain

  • Sweating

  • Headache

  • Acid Or Sour Stomach

  • Excessive Air Or Gas In Stomach

  • Heartburn

  • Skin Rash

  • How long is the duration of effect?

    The effect of this medicine lasts for an average duration of 2 to 3 days.
  • What is the onset of action?

    The peak effect of this medicine can be observed within 1 to 2 hours.
  • Are there any pregnancy warnings?

    This medicine is not recommended for pregnant women.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    This medicine is not recommended for breastfeeding women.

Below is the list of medicines, which have the same composition, strength and form as Sim 5 MG Tablet , and hence can be used as its substitute.

  • Missed Dose instructions

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
  • Overdose instructions

    Seek emergency medical treatment or contact the doctor in case of overdose.
  • India

  • United States

  • Japan

Sim 5 MG Tablet is a lipid-lowering oral medicine that is administered to reduce the risks of heart disorders. It is an inactive lactone that hydrolyzes after it is ingested. It inhibits the HMG coenzyme that is responsible for the production of cholesterol.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    Impaired Liver Function

    Sim 5 MG Tablet should not be used in the patients with liver injury. Frequent monitoring of liver function tests is necessary. Dose adjustments are to be made based on the severity of the liver injury. Discontinue the treatment if symptoms worsen.


    Any symptoms of muscle pain, tenderness or weakness should be reported to the doctor. Inform the doctor if you have any history of muscle disorder.


    Before taking this medicine, inform the doctor if you are suffering from diabetes. Regular blood glucose tests are to be made and appropriate diet should be maintained.
  • Interaction with Alcohol


    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Interaction with Lab Test


    Information not available.
  • Interaction with Food

    Grapefruit juice

    Consumption of grapefruit juice is not recommended when the patient is on Sim 5 MG Tablet. Any symptoms of tenderness, weakness, dark colored urine should be reported to the doctor. Frequent monitoring of kidney function tests are to be made.
  • Interaction with Medicine


    The desired effect of Sim 5 MG Tablet may not be obtained if taken with carbamazepine. Inform the doctor if you are receiving these medicines. Dose adjustments or an alternate medicine should be considered based on the clinical condition.


    The concentration of Sim 5 MG Tablet may increase if taken with ciprofloxacin which may cause a rare but serious condition called rhabdomyolysis. Any symptoms like fever or dark colored urine, muscle pain, tenderness should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.


    You may have muscle pain, tenderness, and dark colored urine if these medicines are taken together. Inform the doctor if you are taking these medicines together. Appropriate dose adjustments are to be made under the doctor's supervision.


    You may experience abdominal pain, diarrhea, muscle pain, and numbness in hands and feet if these medications are taken together. This interaction is more likely to happen in the elderly population with pre-existing kidney disease. Regular kidney function tests should be performed if coadministration is necessary. Appropriate dose adjustments or replacement of the medicine should be done under the doctor's supervision.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Sim 5 MG Tablet
What are the uses of Sim 5 MG Tablet
What are the contraindications of Sim 5 MG Tablet ?
What are the side effects of Sim 5 MG Tablet ?
Key highlights of Sim 5 MG Tablet
What are the substitutes for Sim 5 MG Tablet ?
What are the dosage instructions?
Where is the Sim 5 MG Tablet approved?
How does this medication work?
What are the interactions of Sim 5 MG Tablet ?