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Overview

Quinine 600 MG Tablet

Quinine 600 MG Tablet

Manufacturer: Merck Consumer Health Care Ltd
Medicine composition: Quinine
Prescription vs.OTC: Prescription by Doctor required

Quinine 600 MG Tablet is used in the treatment of malaria, a disease which occurs as a result of mosquito bites. The disease occurs because of malaria parasites that enter the human body as a result of the mosquito bite. These parasites attack the liver and the red blood cells of the body. Quinine 600 MG Tablet is prescribed by doctors as it kills malaria parasites that invade the red blood cells. Thus, Quinine 600 MG Tablet is a part of a group of medicines which are known as antimalarials. Quinine 600 MG Tablet effectively treats malaria, but does not prevent the onset of the disease.

The drug should be taken as per the instructions given by a doctor. It is meant for oral consumption, and it is generally recommended that patients should take it along with food, so as to reduce the chances of a stomach upset. The drug is generally prescribed for about 3-7 days and should be taken after every 8 hours. The dosage and time period of consumption of drug is usually dependent on the severity of your condition and the country you live in. In case of children the dosage is prescribed as per their weight.

Make sure that you do not stop the medicine half way. It is best that you finish the course of the medicine in order to be fully cured of the infection. If you do not complete the prescribed course, it may complicate your condition further.

The drug has a few side-effects which include-

In case any of these side effects persist for a long period of time or become increasingly severe, get in touch with your doctor immediately. Very few patients who are prescribed Quinine 600 MG Tablet suffer from severe side effects like hemolytic anemia, liver or kidney problems, excessive weakness, severe abdominal pain and yellowing of the skin. Medical help should be sought immediately if any of the above rare side effects are experienced.

This medicine is used to treat uncomplicated malaria which is resistant to Chloroquine.
This medicine is not recommended for use if you have a known history of allergy to quinine or other related antimalarial medicines like mefloquine, quinidine etc.
G6PD deficiency
This medicine is not recommended for use in patients having this rare hereditary condition where the red blood cell function is abnormal.
associated blackwater fever
This medicine is not recommended for use in patients having a history of blackwater fever associated with quinine use.
This medicine is not recommended for use in patients suffering from this condition where muscles tire rapidly.
This medicine is not recommended for use in patients suffering from this condition where the nerve fibers of the eye are damaged.
In addition to its intended effect, Quinine 600 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Severe diarrhea Major Common
Nausea and Vomiting Major Common
Severe abdominal pain Major Common
Black or tarry stools Major Less Common
Bloody stool Major Less Common
Blurred vision Major Rare
Anxiety and nervousness Moderate Less Common
Difficult and painful breathing Major Rare
Severe back pain Moderate Less Common
Ringing or buzzing in the ears Major Rare
Swelling of the eyes, ears, and inside of nose Major Rare
Slurred speech Moderate Less Common
Sleeplessness Minor Less Common
Excessive hunger Minor Common
Fast heartbeat Major Common
How long is the duration of effect?
The time duration for which this medicine remains active in the body is subject to variations based on the patient's condition.
What is the onset of action?
The time taken for this medicine to show its effect is not known. However, it is readily available when taken orally and reaches the peak levels within 1-4 hours.
Are there any pregnancy warnings?
Use of this medicine in pregnant women is not recommended unless absolutely necessary and the benefits outweigh the risk associated with use. Consult your doctor using this medicine.
Is it habit forming?
No habit forming tendencies were reported.
Are there any breast-feeding warnings?
Use of this medicine by women who are breastfeeding is not recommended unless necessary. Consult your doctor before using this medicine.
Below is the list of medicines, which have the same composition, strength and form as Quinine 600 MG Tablet, and hence can be used as its substitute.
Ipca Laboratories Pvt Ltd.
Missed Dose instructions
Take the missed dose only if you are late by less than four hours. Do not take extra medicine to make up for the missed dose.
Overdose instructions
Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include nausea, vomiting, headache, abdominal pain, change in the heartbeat, excessive sweating etc.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Disease
Information not available.
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Ketoconazole Moderate
Report the use of either of the medicine to the doctor. You may require frequent monitoring while taking these medicines together. Any side effects experienced while taking these medicines should be reported to the doctor immediately.
Amiodarone Major
Report the use of either of the medicine to the doctor. The risk of adverse effects on the heart is significantly high especially if there is an active illness. You doctor may determine the best course of treatment in such cases.
Pimozide Major
Report the use of either of the medicine to the doctor. The risk of adverse effects on the heart is significantly high especially if there is an active illness. You doctor may determine the best course of treatment in such cases.
Quinidine Major
Report the use of either of the medicine to the doctor. The risk of adverse effects on the heart is significantly high especially if there is an active illness. You doctor may determine the best course of treatment in such cases.
Aminophylline Moderate
Report the use of either of the medicine to the doctor. You may require frequent monitoring while taking these medicines together. Any side effects experienced while taking these medicines should be reported to the doctor immediately.
Atorvastatin Moderate
Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent clinical monitoring while using these medicines together. It is likely that the current medication may be substituted with suitable alternatives that do not interact.
Ritonavir Major
Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent clinical monitoring while using these medicines together. It is likely that the current medication may be substituted with suitable alternatives that do not interact.
Magnesium/Aluminum containing medicines Major
Report the use of medicines containing aluminum/magnesium to the doctor before receiving this medicine. The risks of adverse effects are significantly high while using them together. Your doctor may devise a suitable dose plan with appropriate timings of uptake if these medicines are to be taken together.
Sodium bicarbonate Moderate
Report the use of sodium bicarbonate or any other urinary alkalizer to the doctor before receiving this medicine. You may require a dose adjustment and more frequent clinical monitoring to safely use these medicines together.

Popular Questions & Answers

What are the symptoms of malaria. I don't have till any medicine tell me name of medicine also.

Diploma in Diabetology, Pregnancy & Diabetes, Hypertension, Cardiovascular Prevention in Diabetes ,Thyroid
Sexologist, Sri Ganganagar
Common symptoms of malaria include: shaking chills that can range from moderate to severe. High fever. Profuse sweating. Headache. Nausea. Vomiting. Abdominal pain. Diarrhea. Malarone, which is a combination of two antimalarial medicines (atovaquone and proguanil). Malarone is taken to treat malaria caused by chloroquine-resistant P. Falciparum. Quinine plus an antibiotic such as clindamycin, doxycycline, or tetracycline for most P. Falciparum infections.

I am suffering from some Blood related problem like platelet still near 75000 and TLC is around 3200 What I will do to overcome from this problem.

MBBS
General Physician, Cuttack
I am suffering from some Blood related problem like platelet still near 75000 and TLC is around 3200 What I will do t...
Low platelet count could be due to 1. Dehydration, vitamin b12, folic acid dficiency, pregnancy 2.Leukemia,Aplastic anaemia, ITP 3. Heavy alcohl consumption, Liver failure 4.Systemic bacterial/viral infection 5.Dengue fever 6.Effect of drugs like sulfur containing antibiotic, quinine, heparin, valproic acid, Anti neoplastic drugs likemethotrexate, antacid Treatment Take 1.Papaya,Pomegranate, milk, 2.Diet rich in folic acid like orange juice, spinach, chicken, Fish 3.Vitamin A rich food like carrot, pumpkin, sweet potato, 4.Vitamin K rich food like egg, vegetables, whole grain, organic bean etc 5.Consult physician for further advice and treatment.

I have Tinnitus Ringing in both ears since January 2016 .I consult many doctors but Issue not resolved. I have also done audiometry test. The result Is normal .no hearing loss. But I want Permanent Resolution For tinnitus. Plzzz help me in that. And which Medicine will Give mi 100% Result. Should I go for allopathy or Should I go for Ayurvedic treatment. Or Homeopathy?

MBBS
General Physician, Cuttack
.1.It is due to exposure to loud noise, stress, fatigue, 2.medication like over use of Aspirin, quinine, Antibiotic, Anti depressants, 3.ear injury (externa/middle/internal/Auditory nerve problem), cold, wax in ear 4.labyrinthitis,otosclerosis, 5.Get yourself examined by ENT specialist and follow the advice and treatment.

I'm using melamet cream since 10 months I got positive effects but after some reviews I heard that it's bad for skin. I have even heard that using hydro quinine 2% doesn't cause any harm. I have stopped using this cream since 10 days didn't find any changes on my face. I have 2 questions is there any chances of turning black again if yes then how to maintain that fairness which has come to my face? Please help me and do the needful please.

C.S.C, D.C.H, M.B.B.S
General Physician,
I'm using melamet cream since 10 months I got positive effects but after some reviews I heard that it's bad for skin....
Apple is a miracle fruit for the skin.The alpha hydroxy acids or AHA's present in apples improves skin color and elasticity of the skin.Soak peeled apple slices in milk for 20 minutes and then blend to form a creamy paste.Place in the freezer for 10 minutes, and then mix a tsp of lemon .
2 people found this helpful

Is there a permanent cure for tinnitus? Is there a home remedy? Please suggest me a doctor in Asansol who can treat this condition successfully.

MBBS
General Physician, Cuttack
Tinnitus It is a ringing sensation in ear. It is due to exposure to loud noise, stress, fatigue, medication like over use of Aspirin, quinine, Antibiotic, Anti depressants, overuse of aminoglycosides, erythro/vanco/neomycin/lasix, age related hearing loss, ear injury (externa/middle/internal/Auditory nerve problem), Loud noise,(some times due to cold and disappear within a week/wax in ear), drug, chemical, labyrinthitis, otosclerosis, menier?s disease (dizziness with Tinnitus) Acoustic neuroma (Tumor on acoustic nerve), head/neck Injury TMJ problem (temporo mandibular joint). It may lead to deafness. No definite surgical treatment available. Treatment- Hearing Aid/masking device, Therapeautic noise generator, Tinitus refraining therapy (TRT), Cognitive behavior therapy. Avoid smoking, Tea, coffee, chocolate Consult a good ENT specialist for proper advice.
1 person found this helpful

Popular Health Tips

Malaria During Pregnancy - 4 Ways it Can be Treated!

MD - Obstetrics & Gynaecology, MBBS
Gynaecologist, Noida
Malaria During Pregnancy - 4 Ways it Can be Treated!

Malaria is a disease that is caused by the bite of a certain mosquito or protozoan parasite. This can attack the red blood cells and is mainly found in tropical as well as subtropical areas. Until recently, there was little chance of recovering from this ailment. Yet, in today's day and age of great medical advancement, it has become possible to cure a patient suffering from this disease with the help of timely and proper diagnosis. This disease becomes even more complicated and problematic when it affects pregnant women.

The ways in which this disease can be treated during pregnancy is as follows:

  1. Medication therapy: If woman is found to be suffering from this disease in the second or third trimester of their pregnancy, they may be prescribed artemisinin-based therapy. This therapy can be used only if the pregnant lady is not suffering from any other kind of complications like heart conditions, diabetes and high blood pressure, during the pregnancy. This medicine is short-acting, with artemether or artesunate,which can greatly reduce the number of parasites that may have invaded the red blood cells.
  2. Other antimalarials: The treatment of this disease for pregnant women can also be done with the help of other antimalarials, which should typically be prescribed and administered in a clinical setting. These also include quinidine gluconate which can be used in place of the IV quinine in order to bring down the number of parasites in the body. This will lessen the attack on the red blood cells to a great degree. Lumefantrine tablets may also be used in such cases. Also, the doctor will have to first try a test dose to ensure that the patient is not allergic to any of the elements or compounds of these medicines.
  3. Monitoring: Pregnant women suffering from malaria will need to get their blood samples tested on a regular basis. The blood smears will usually be tested daily to check whether the body is responding adequately to the treatment. This will also ensure that the doctor knows when to change the dose or the drug involved.
  4. Diet and exercise: The patient will be asked to stick to the normal diet and activity levels. Yet, care must be taken to avoid any situation where fatigue might set in, as this can aggravate the condition. One must also increase the intake of water to ensure that the body is always well hydrated. This helps the body in bouncing back to normal as the toxins are continuously flushed out, and the immunity system is better equipped to fight the disease causing parasites.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2910 people found this helpful

Food Items To Be Avoided By Patients With Low Platelet Count

MD - Pathology
Pathologist, Noida
Food Items To Be Avoided By Patients With Low Platelet Count

Now this is a very interesting topic. We have always focused on food items which help raise platelet counts. So, this topic is equally important, if not more. This blog lists various food items that are best avoided in patients having low platelet counts. Scientific evidence is lacking, in majority, on why these food items are best avoided. Most of these are gradual observations that people have noticed over the years.

So the list goes as :

  1. Ginkgo Biloba – used as a memory enhancer
  2. Ginseng – used as energy boosting supplement
  3. Raw garlic
  4. Pomegranates
  5. Omega three intake foods – fish etc
  6. Red wine
  7. Smoking
  8. Pineapple – which are considered as antiplatelet agents
  9. Fruits and vegetables that contain “salicyclates” - such as cucumbers, mushroom, raddish, berries, cherries. Salicyclates act as blood thinners and prevent clotting
  10. Coffee – it is not the caffeine but phenolic acids present in coffee that are the culprit.
  11. Alcohol
  12. Foods containing quinine – ex. Tonic water – a bitter liquid which is used as a mix for alcoholic drinks
  13. Foods containing Aspartame: Aspartame is a low calorie sweetener. It is used in diet sodas, energy drinks, protein shakes, flavoured milk and juices, breath mints and jellies. In fact ice-creams, and chewing gums and ketchups may also contain aspartame.
  14. The above food items are to be best avoided if you suffer from dengue.

    But if your low platelet counts are diagnosed due to autoimmune diseases ( such as celiac disease), then additionally you need to take an anti-inflammatory diet along with avoidance of gluten containing foods. Now gluten containing foods are wheat, barley, rye and other grains. So these items should not be consumed if you suffer from celiac disease – a type of autoimmune disease. Anti-inflammatory diet means including fresh food in diet, minimize processed food and fast food, eat more fruits and vegetables, restrict caloric intake to 2000 to 3000 calories per day in adults. Of this caloric intake, 40-50% should come from carbohydrates, 30 % from fats, and 20 -30% from proteins. 

5 people found this helpful

A Penis Rash May Develop Due to Fixed Drug Eruption!

MD - General Medicine
Sexologist, Delhi
A Penis Rash May Develop Due to Fixed Drug Eruption!

Many men begin their daily penis examination during their morning shower, and one of the last things they want to discover as the water cascades across them is a penis rash that wasn't there when they went to bed. Kudos are certainly due to these men for making penis health the priority it deserves to be; now they need to figure out what might be causing this unwelcome penis rash. That's why it's good to know about a fixed drug eruption and its relationship to a penis rash.

Fixed drug eruption

A fixed drug eruption is an allergic reaction to a particular medication or medications. If a person is allergic to multiple drugs and is taking them at the same time, multiple fixed drug eruptions may occur. The term "eruption" refers to the fact that the allergic reaction shows up on the skin in the form of lesions - or "erupts" onto the skin.

Most often, these lesions are round or oval patches of swollen skin, typically reddish in color at the start but often changing to brown or purple. There may be a blister accompanying the lesion, typically staying within the area of the lesion.

Why is it called a "fixed" drug eruption? The fixed refers to the fact that the lesion tends to show up in the same general area whenever the drug is taken. However, it should be noted that, with repeated use, the lesions may also start showing up on other parts of the body. So if a fixed drug eruption is first noticed on the penis, it may continue to recur there, but it may also show up on the lips, the hands, the feet, etc.

The lesions

In most cases, lesions will appear between 30 minutes to 8 hours after administration of the drug. Often one lone lesion will appear at first. With repeated doses of the drug, it may either grow larger or more lesions may appear. Over time, especially after cessation of the drug, the lesions will "scab over." In most cases, they will disappear altogether at some point after the drug is no longer taken.

When the lesions are in a group, it may give the appearance of a penis rash. If solitary, it may seem more like a blister or blemish. In either case, it tends to be unattractive. More importantly, it gives the appearance of something contagious and possibly infectious.

In fact, penis rash from a fixed drug eruption is neither contagious nor infectious. However, because it looks as if it could be, it can be off-putting to partners, who may wish to avoid touching the penis until the rash is gone.

Discomfort

The lesions can also cause some discomfort for the man on whose penis they reside. They can be itchy in some cases. For some, they make the skin feel tender, which may decrease a man's desire for or enjoyment of sex (whether with a partner or by himself).

Causes

There are many, many drugs that have been implicated in the appearance of a fixed drug eruption. These include many forms of aspirin, many antibiotics, non-steroidal anti-inflammatories, sedatives and quinine.

If a penis rash (or rash elsewhere on the body) results from a fixed drug eruption, a doctor should be consulted to determine if an alternative medication may be used that might not have this side effect.

As a fixed drug eruption heals and the penis rash goes away, the skin may be in need of repair. Once any blistering has disappeared, using a first class penis health crème (health professionals recommend Man1 Man Oil, which is clinically proven mild and safe for skin) may help. The skin may need to be rehydrated so that it regains elasticity and suppleness. Using a crème with a combination of a natural moisturizer (such as vitamin E) and a high-end emollient (like Shea butter) will produce better results. Also important: Be sure the crème includes vitamin C, due to the role it plays in proper collagen production.

3 people found this helpful

Principle of Similars in Homeopathy

BHMS
Homeopath, Gurgaon
Principle of Similars in Homeopathy

Law of Similars

Homeopathy is a department of natural medicine based on the Principle of Similars and a non-toxic system of experimental science of therapeutics originated in Germany. From Germany (year 1796) homeopathy spreads to Austria (1816) and then to the rest of the Europe. The birth date of the founder and father of Homeopathy i.e. 10 April every year is celebrated as ‘World Homeopathy Day’ and the week following his birthday (10-16th April) is celebrated as ‘World Homeopathy Awareness Week’

Principle of similar (Let likes be treated by likes) talks about the pathogenetic and symptomatic similarity between the drug and the disease and is stated as

The drug which is most likely to cure or relieve a case of disease is that which when administered to a healthy person, has shown itself capable of producing symptoms and change in sensation experienced which most closely resemble those of the case of disease.

In 1790, he discovered principle of similar when he found that drug which was known to be curative actually produces those very symptoms when given to a healthy person. He said, “Substances which arouse a kind of fever extinguish the types of intermittent fevers…Cinchona cures intermittent fever by virtue of its power to produce in the healthy, a similar affection”. But the principle was published in 1796.

The same drug acts differently when given to a person under conditions of disease from what it would do in the same person when in health. The powers of any drug over the human organism, is the sum-total of the symptoms and alternations it has caused when introduced into a healthy organism, and the symptoms and morbid changes it has removed when given to the sick 

In other words, the specific curative property of a drug lies in its power of producing similar symptoms in a healthy individual i.e. the drugs have sickness-making as well as sickness curing properties, the sickness being the same [3]. What a drug can cause it can cure; and that if you want to know what a drug can cure, you have only to discover what it can cause 

Homoeopathy maintains that there is a constant relationship between the effect of drugs on the healthy and the curative reactions they call forth in the sick, so, clearly, you must test drugs on healthy people. If a compound caused symptoms in healthy volunteers, it should then also serve as a remedy for patients who actually suffer from such symptoms.

Hahnemann found that when a medicine was able to produce changes similar in nature and expression to that of the natural disease in the patient, it stimulated a response in spite of obstacles or sluggishness of the system. This response was the natural one the body used in curing itself. The response was a temporary aggravation of one or more symptoms followed by quick amelioration.

Disease can be cured by a medicinal substance given in small doses that produces similar symptoms in health people when given in large doses. In simple words, the medicine can cure when given in picogram doses what it can cause in milligram doses.

1. Red onion when peeled makes your eyes water and your nose burn. If you are having an attack of hay fever/common cold with watering eyes and a burning nose or a cold which is ‘worse indoors, better in open air’, a homeopathic remedy made from onion called allium cepa can relieve it.

2. Poison ivy causes redness, intense itching, burning, blistering and sometimes stiff muscles. Potentised poison ivy called as rhus tox (a homeopathy medicine) has been used for herpes, burns, eczema, allergy, arthritis, etc.

3. When you are stung by a bee you feel a burning, stinging pain and the tissues surrounding the area swell up. Some relief is gained from applying cold to the area. If you had swollen tonsils with burning and stinging pain relieved by cold, a homeopathic remedy prepared from the same source Apis Mellificia could cure.

4. Coffee keeps people awake and alert. A remedy prepared from coffee called Coffea cruda in very small doses might be appropriate for helping someone with insomnia with an overly alert mind.

5. Eyebright causes a clear and bland nasal discharge along with tears that burn and irritate the skin under the eye. The homeopathic medicine Euphrasia prepared from eyebright cures it.

6. Quinine (derived form Cinchona bark) given in daily doses to a healthy person can cause symptoms similar to malaria. Indeed, the Cinchona officinalis, a homeopathic medicine prepared from cinchona bark, is curative in many patients with malaria.

7. White Hellebore, in large doses, causes violent purging that leads to severe dehydration-symptoms similar to choleraVeratrum album, a homeopathic medicine prepared from White Hellebore is effective against cholera

8. Belladonna, a homeopathic medicine, is used to treat scarlet fever (fever due to Group A Streptococcal (bacterial) Infection), since the symptoms of belladonna poisoning closely resemble those of scarlet fever

9. Human body can tolerate about 7 grams of salt per day, but if we triple it and give 21 grams per day, we will have a very sick person within a fortnight with a host of symptoms peculiar to the substance given in high enough doses. A medicine prepared from common salt called Natrum mur can cure host of diseases ranging from hypertension to depression.

 

2 people found this helpful

Malaria - Signs You Must Not Ignore!

MBBS, AFIH, PGDMLS, MD-HRM, MD-HM
General Physician, Gurgaon
Malaria - Signs You Must Not Ignore!

Mosquitoes might be tiny creatures, but are responsible for some of the most dreadful diseases, one of them is malaria. Malaria is caused by a parasite that is transmitted through mosquito bites directly or from mother to unborn baby and through blood transfusions. Very widely spread in the Asian and African continents, people travelling here are very cautious of this disease. In areas that are notorious for mosquito infestations, the local people also take preventive measures to ensure mosquito breeding is prevented or at least minimised.

Spread of the disease: When a mosquito bites an infected person, it picks up the parasite from the person and when it next bites another person, the infection is also transmitted. From there, the parasite travels to the liver and into the bloodstream before reaching another individual. While all people are prone to getting the infection, elderly people, children, pregnant women, and immunocompromised people are at greater risk. Also, new travellers are at greater risk than local people, who are to some extent immune to mosquito bites.

Symptoms: The disease is characterised by moderate to severe shaking chills which are more common in the evening, high fever, profuse sweating, headache, vomiting, and diarrhoea. Quite often, there is about a 4-week gap between the time of the mosquito bite and the onset of symptoms. However, in many people, the disease could lie dormant and symptoms manifest when the immunity is severely lowered.

With the gradual progression of the disease, more severe symptoms could evolve as below, and that is when malaria becomes life threatening.

  1. Cerebral malaria: Once the parasites enter the bloodstream, they can block the minor blood vessels in the brain leading to cerebral oedema and even brain damage. It could eventually result in coma.
  2. Anaemia: There is large-scale destruction of red blood cells, leading to severe anaemia and weakness and fatigue
  3. Breathing problems: Similarly, accumulation of fluid in the lung spaces can lead to pulmonary oedema which causes difficulty breathing and lung failure.
  4. Organ failure: Blood flow blockage to other vital organs like kidneys, liver, and spleen are also possible. The spleen may rupture leading to severe haemorrhage.
  5. Low blood sugar: The malarial parasite per se and the most commonly used medicine (quinine) are both known to cause low blood sugar levels. This can result in coma and even death.

Once the diagnosis is confirmed, treatment usually consists of chloroquine, Mefloquine, quinine sulfate, or hydroxychloroquine. There are various drug-resistant forms of malaria, and they may require combination therapy.
Prevention assumes greater significance with travellers going for vaccines prior to visiting these areas. Even the local people should find ways to avoid breeding of mosquitoes, use mosquito repellents and nets to avoid the infection.

6062 people found this helpful