Get Dettol Kit worth Rs. 130 for just Rs. 4
Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}
Overview

Perampanel

Prescription vs.OTC: Prescription by Doctor required

Perampanel is used in combination with other medications to treat certain types of seizures in people who are 12 years of age or older. This medication comes under class of medication known as anticonvulsants.It works by decreasing abnormal electrical activity in the brain.

Precautions:Before taking this medications inform your doctor or pharmacist about what prescription and non- prescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.Be sure to mention any of the following: antidepressants; barbiturates such as phenobarbital and secobarbital (Seconal); medications for allergies,anxiety, cough and cold, mental illness, and pain; medications for seizures such as carbamazepine (Carbatrol, Tegretol, Equetro),Also inform your doctor and pharmacist if you are allergic to medication or any other medications.Inform your doctor and pharmacist if you are pregnant or plan to become pregnant.Also avoid this medication during nursing. This medication may cause dizziness, drowsiness, and problems with coordination and balance. This may increase the risk of falls that can cause serious injury, especially if you are elderly. Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how this medication affects you.Side effects:Constipation, nausea, muscle or joint pain, blurred or double vision, drowsiness.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.

In addition to its intended effect, Perampanel may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Is It safe with alcohol?

There is no data available. Please consult doctor before consuming the drug.

Are there any pregnancy warnings?

There is no data available. Please consult doctor before consuming the drug.

Are there any breast-feeding warnings?

There is no data available. Please consult doctor before consuming the drug.

Is it safe to drive while on this medicine?

There is no data available. Please consult doctor before consuming the drug.

Does this affect kidney function?

There is no data available. Please consult doctor before consuming the drug.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which contains Perampanel as ingredient
Eisai Pharmaceuticals India Pvt Ltd
Eisai Pharmaceuticals India Pvt Ltd
Eisai Pharmaceuticals India Pvt Ltd
Perampanel is a non-competitive antagonist of AMPA glutamate receptor used to treat partial onset epileptic seizures. Inhibition of AMPA receptor inhibits neuronal excitation in the central nervous system, reducing psychomotor performance and seizure symptoms.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Health Tips

Seizures - 3 Ways It Can Be Treated!

MCh - Neurosurgery, MS-General Surgery, MBBS
Neurosurgeon, Delhi
Seizures - 3 Ways It Can Be Treated!

The primary aim of the treatment in patients suffering from seizure is leasing a seizure-free life without giving way to any adverse effects. This goal can be accomplished in over 60 percent people with the help of anticonvulsants. Some patients also experience adverse effects since they suffer from a seizure which is refractory to medical therapy. Here are some of the common treatment options for seizures:

  1. Monotherapy: Sometimes, monotherapy is given as it reduces the chance of all sorts of adverse effects and even avoids drug interactions. Moreover, this type of treatment approach is much less expensive than polytherapy since many older generation of the anticonvulsant agent comprises of hepatic enzyme which is responsible for reducing the serum level of the concomitant drug which leads to an increase in the dosage level of such medicines.
  2. Social And vocational rehabilitation: People suffering from problems in psychosocial adjustments after the diagnosis may also need social and vocational rehabilitation. Many physicians do not pay enough attention to the consequences that an epilepsy diagnosis may leave on the patient. For instance, people with epilepsy may have a fear of experiencing next attack of seizure and they may be unable to work at heights or drive.
  3. Consulting an expert: It is important to refer patients with intractable spells to epileptologist or neurologist for subsequent workup. A neurosurgical consultation may also be needed when the patient has to be treated surgically.

Importance of anticonvulsant therapy

Patients who have had already suffered from recurrent attacks of unprovoked seizure may need treatment with an anticonvulsant. This treatment is not recommended until the person has risk factors for suffering from the problem yet again. The primary means of treating seizure is anticonvulsant therapy where the most suitable drug is chosen based on accurate diagnosis of the syndrome as a response to specific anticonvulsants may vary from one patient to another. The difference in response may reflect the various pathophysiologic mechanisms in different types of seizures.

Types of anticonvulsant therapy
Some of the anticonvulsant therapy medication may have multiple action mechanism while some have an only single mechanism of action. Some of the most common variants of the therapy include:

  1. Neuronal potassium channel referred to as KCNQ opener
  2. Blockers of unique binding sites such as perampanel, gabapentin, and levetiracetam
  3. H-current modulators such as lamotrigine and gabapentin
  4. Carbonic anhydrase inhibitors such as zonisamide and topiramate
  5. Alpha-amino 3-hydroxy 5-methyl 4-isoxazole propionic acid receptor blockers like topiramate and perampanel.
  6. N and L-calcium channel blockers like zonisamide, valproate, topiramate, and lamotrigine

Even though there are so many types of drugs available, all of them cannot be used for the treatment of seizures. Doctors would evaluate the condition thoroughly before prescribing a medication that can be helpful in reducing the severity of the condition.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2745 people found this helpful
Table of Content
About Perampanel
What are the side effects of Perampanel ?
Key highlights of Perampanel
Medicines containing Perampanel
How does medicine works?