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Overview

Novastat Gold Tablet

Manufacturer :  Lupin Ltd
Medicine Composition :  Quinidine, Rosuvastatin, Clopidogrel
Prescription vs OTC : Prescription by Doctor required

About Novastat Gold Tablet

Novastat Gold Tablet is helpful in treating the problem of irregular heartbeats and heart arrhythmias such as atrial fibrillation. It can be helpful by reducing the number of irregular heartbeats and by blocking abnormal heartbeat signals.

Your doctor may also prescribe certain other drugs in combination with these medicines like blood thinners, anticoagulants and beta-blockers. This is done to reduce any blood clots in the heart and to slow down the pulse rate.

Before using this medicine, please check whether you are allergic to it or any of its constituents. Consult your doctor before taking this medication. Inform the doctor about your medical history and allergies. It is advised to consume this drug with a glass full of water. The best way to take this drug is on an empty stomach.

The dose and duration of this drug is dependent on the patient’s medical condition. Hence, consult your doctor for details regarding dosage. Avoid the consumption of grapefruit juice during the course of medication as it can cause interference with the mechanism of medicine. The amount of salt you consult in your food can also change the amount of absorption of this drug. It is important to keep your doctor updated if your medical condition does not approve after this drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Novastat Gold Tablet

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Novastat Gold Tablet ?

    • Hypersensitivity

    • Thrombocytopenia

    • Prolong Qt Interval

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Novastat Gold Tablet ?

    • Severe Diarrhea

    • Nausea Or Vomiting

    • Loss Of Appetite

    • Stomach Pain

    • Heartburn

    • Change In Vision

    • Eye Pain

    • Hypoglycaemia (Low Blood Sugar Level)

    • Easy Bruising And Bleeding

    • Excessive Tiredness

    • Dark Urine

    • Skin Yellowing

    • Hypotension

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Novastat Gold Tablet

    • Are there any pregnancy warnings?

      Please consult your doctor and take all the necessary precautions as this drug is probably unsafe to be used during pregnancy.

    • Are there any breast-feeding warnings?

      The drug can pass through milk, hence exercise caution if you are taking this medicine.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Does this affect kidney function?

      Please consult your doctor before taking this medication if you have kidney problems. Caution must be taken. Adjustment of dose is needed.

    • Does this affect liver function?

      Please consult your doctor before taking this medication if you have liver problems. Adjustment of dose is needed. Larger loading dose may be indicated, reduce maintenance doses by 50% and monitor serum levels closely.

    • How long is the duration of effect?

      The drug remain active for about 6 - 8 hours after its administration.

    • What is the onset of action?

      The action of this drug is initiated within 60 minutes after its administration.

    • Is it safe to drive while on this medicine?

      No information available

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the substitutes for Novastat Gold Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Novastat Gold Tablet , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      In case of an overdose, you may experience some side effects. Therefore, it is advised to take medical help immediately.

    • Are there any missed dose instructions?

      It is advised to not to miss a dosage since there is just one dose per day. Consume the missed dosage as soon as you remember.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Novastat Gold Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    This medication works by decreasing myocardial excitability and conduction velocity, and myocardial contractility by decreasing sodium influx during depolarization and potassium efflux in repolarization It also depresses phase O of the action potential and lastly it also reduces calcium transport across the cell membrane.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Novastat Gold Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        • Amiloride may cause prolonged ventricular conduction leading to arrhythmias.
        • Amiodarone may increase quinidine blood levels; monitor quinidine levels.
        • Cimetidine: Increase quinidine blood levels; closely monitor levels or use an alternative H2 antagonist.
        • Cisapride and quinidine may increase risk of malignant arrhythmias; concurrent use is contraindicated.
        • Codeine: Analgesic efficacy may be reduced.
        • Digoxin blood levels may be increased. Monitor digoxin blood levels.
        • Enzyme inducers (aminoglutethimide, carbamazepine, phenobarbital, phenytoin, primidone, rifabutin, rifampin) may decrease quinidine blood levels.
        • Metoprolol: Increased metoprolol blood levels.
        • Mexiletine blood levels may be increased.
        • Nifedipine blood levels may be increased by quinidine; nifedipine may decrease quinidine blood levels.
        • Drugs which prolong the QT interval include amiodarone, amitriptyline, astemizole, bepridil, disopyramide, erythromycin, haloperidol, imipramine, pimozide, procainamide, sotalol, and thioridazine. Effects may be additive; use with caution.
        • Propafenone blood levels may be increased.
        • Propranolol blood levels may be increased.
        • Ritonavir, nelfinavir and amprenavir may increase quinidine levels and toxicity; concurrent use is contraindicated.
        • Sparfloxacin, gatifloxacin, and moxifloxacin may result in additional prolongation of the QT interval; concurrent use is contraindicated.
        • Timolol blood levels may be increased.
        • Urinary alkalinizers (antacids, sodium bicarbonate, acetazolamide) increase quinidine blood levels.
        • Verapamil and diltiazem increase quinidine blood levels.
        • Warfarin effects may be increased by quinidine; monitor INR closely during addition or withdrawal of quinidine.
      • Interaction with Food

        Excessive intake of fruit juices or vitamin C may decrease urine pH and result in increased clearance of quinidine with decreased serum concentration. Alkaline foods may result in increased quinidine serum concentrations. Food has a variable effect on the absorption of the sustained-release formulation.
      • Interaction with Disease

        Monitor and adjust dose to prevent QTc prolongation. Watch for proarrhythmic effects. May precipitate or exacerbate CHF. Reduce dosage in hepatic impairment. In patients with atrial fibrillation or flutter, block the AV node before initiating. Correct hypokalemia before initiating therapy. Hypokalemia may worsen toxicity. Use may cause digoxin-induced toxicity (adjust digoxin's dose). Use caution with concurrent use of other antiarrhythmics. Avoid use in myasthenia gravis (may worsen condition). Can unmask sick sinus syndrome (causes bradycardia). Has been associated with severe hepatotoxic reactions, including granulomatous hepatitis. Hemolysis may occur in patients with G-6-PD (glucose-6-phosphate dehydrogenase) deficiency.

      FAQs about Novastat Gold Tablet

      • Ques : Is it safe to take Novastat Gold Tablet before surgery?

        Ans : It is advised to not take Novastat Gold Tablet before surgery, and if it is taken notify your doctor. Novastat Gold Tablet may cause adverse effects and may interfere with surgical procedures.

      • Ques : Is Novastat Gold Tablet safe for patients suffering from heart disease?

        Ans : Novastat Gold Tablet should be used with care in patients suffering from heart disorders as it may affect the heart rhythm and blood pumping capacity. Based on the disorder and condition, alternative medicine may also be considered.

      • Ques : How is Novastat Gold Tablet administered?

        Ans : Novastat Gold Tablet is administered orally and its dosage depends on the age, condition, and medical history. Novastat Gold Tablet should be taken as directed.

      • Ques : How is Novastat Gold Tablet stored and disposed of?

        Ans : Novastat Gold Tablet should be stored at room temperature in darkness, in its original packaging.

      • Ques : Are regular checkups necessary while taking Novastat Gold Tablet?

        Ans : it is important to get regular checkups for kidney, liver, and heart function while taking Novastat Gold Tablet.

      • Ques : What are the dietary instructions with Novastat Gold Tablet?

        Ans : It is advised to not consume grapes as it may delay the absorption of Novastat Gold Tablet. Additionally, do not change the salts in your diet while taking this medication without consulting your doctor first.

      • Ques : What is the route of elimination of Novastat Gold Tablet?

        Ans : When the pH of the urine is below 7, 20% of the Novastat Gold Tablet is eliminated via the urine. This number goes down by 5% if the pH of the urine is above 7.

      • Ques : What is the half-life of Novastat Gold Tablet?

        Ans : The half-life of Novastat Gold Tablet is between 6 to 8 hours.

      References

      • Aspirin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 28 May 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/aspirin

      • Aspirin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 28 May 2022].Available from:

        https://go.drugbank.com/drugs/DB00945

      • ASPIRIN capsule,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 28 May 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ASPIRIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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