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Prescription vs.OTC: Prescription by Doctor required
Last Updated: March 31, 2022

Methoxsalen is prescribed for the treatment of vitiligo, along with regulated quantities of ultra-violet light or even sunlight. The drug is known to be a psoralen, which is combined with light therapy to treat damaged skin.

This medicine is also prescribed as a repigmenting agent in vitiligo, and used in conjunction with controlled doses of UVA or sunlight. Its symptoms of overdose include nausea, severe burns; follow accepted treatment of severe burns; keep room darkened until reaction subsides (8-24 hours or more).

The drug should not be used if you are allergic to any component present in it. Individuals who have health problems like melanoma and sensitivity to sunlight should also avoid this treatment. Ask your doctor for more information about how the treatment works, before you decide to undergo it. Also provide him with a detailed medical history and a list of medicines that you are currently on.

The drug is generally applied under the guidance of a medical professional. It is generally applied on lesions that can be hidden from sunlight. Because this is a topical lotion, it does not result in side effects in most individuals. However, in some cases it can lead to some serious side effects like sore and reddened skin, blistering and swelling of the skin followed by peeling. If you do experience any skin discomfort, seek medical help immediately.

Methoxsalen also increases the possibilities of developing cancer of the skin, thus details of its risks and benefits should be thoroughly considered with you medical professional before opting for such a treatment.

This medication is used in conjunction with specific ultraviolet treatment. Follow prescriber's directions exactly for oral medication which can be taken with food or milk to reduce nausea. Consult prescriber for specific dietary instructions. Avoid use of any other skin treatments unless approved by prescriber.

Control exposure to direct sunlight as per prescriber's instructions. If sunlight cannot be avoided, use sunblock (consult prescriber for specific SPF level), wear protective clothing and wraparound protective eyewear. Consult prescriber immediately if burning, blistering, or skin irritation occur.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Dermatologist before using this medicine.

The primary use of this medication is as follows:

The medication is known to cause fewer side effects like:

  • Redness Of Skin

  • Blisters On Skin

  • Edema (Swelling)

  • Itching

  • Pruritus

  • Hypopigmentation

  • Rash

  • Is It safe with alcohol?

    Interaction with alcohol is unknown. Please consult your doctor.
  • Are there any pregnancy warnings?

    Is unsafe to use during pregnancy. There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Unknown. Human and animal studies are not available. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    There is no data available. Please consult doctor before consuming the drug.
  • Does this affect kidney function?

    There is no data available. Please consult doctor before consuming the drug.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.
  • Are there any missed dose instructions?

    If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
  • Are there any overdose instructions?

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Below is the list of medicines, which contains Methoxsalen as ingredient

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This medicine is also known as psoralen and is primarily used to treat vitiligo. It causes interference to deoxyribonucleic acid synthesis. On activation, Methoxsalen attaches to guanine as well as cytosine moieties of DNA causing a cross-linking of this DNA. In the process, the function and synthesis of DNA are inhibited.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine

    Increased toxicity: Concomitant therapy with other photosensitizing agents such as anthralin, coal tar, griseofulvin, phenothiazines, nalidixic acid, sulfanilamides, tetracyclines, thiazides.
  • Interaction with Disease

    Family history of sunlight allergy or chronic infections; lotion should only be applied under direct supervision of a physician and should not be dispensed to the patient; for use only if inadequate response to other forms of therapy, serious burns may occur from UVA or sunlight even through glass if dose and or exposure schedule is not maintained; some products may contain tartrazine; use caution in patients with hepatic or cardiac disease.
  • Interaction with Food

    To reduce nausea, oral drug can be administered with food or milk or in 2 divided doses 30 minutes apart; avoid furocoumarial-containing foods (limes, figs, parsley, celery, cloves, lemon, mustard, carrots).

Ques: What is Methoxsalen?

Ans: Methoxsalen is prescribed for the treatment of vitiligo, along with regulated quantities of ultraviolet light or even sunlight. The drug is known to be a psoralen, which is combined with light therapy to treat damaged skin.

Ques: What are the uses of Methoxsalen?

Ans: Methoxsalen acid used for the treatment of Vitiligo and Psoriasis.

Ques: How long do I need to use Methoxsalen before I see improvement in my condition?

Ans: This medication is to be taken till the time you see an improvement in your health conditions.

Ques: At what frequency do I need to use Methoxsalen?

Ans: This medication should be taken in the dosage as prescribed by the doctor.

Ques: Should I use Methoxsalen empty stomach, before food or after food?

Ans: This medication should be taken after food in a prescribed dosage.

Ques: What are the instructions for the storage and disposal of Methoxsalen?

Ans: This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Methoxsalen
What are the uses of Methoxsalen
What are the contraindications of Methoxsalen ?
What are the side effects of Methoxsalen ?
Key highlights of Methoxsalen
What are the dosage instructions?
Medicines containing Methoxsalen
How does this medication work?
What are the interactions of Methoxsalen ?
FAQs about Methoxsalen