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Overview

Eflornithine

Prescription vs.OTC: Prescription by Doctor not required

Eflornithine is used for slowing down or lessening the growth of facial hair in women. It is an enzyme inhibitor, and works by blocking the enzyme required for facial hair to grow.

Do not use Eflornithine if you are allergic to any of the ingredients present in Eflornithine. Before using Eflornithine tell your doctor if you are using any prescription drugs, non-prescription drugs, or other herbal and dietary pills and supplements, if you are allergic to certain food items or substances, if you are pregnant and/or breastfeeding, or if you have any broken skin, or any kind of sores or boils on the affected area.

Eflornithine comes in the form of a cream, which has to be applied to the affected areas of the face and/or the chin. You cannot wash the area for up to 4 hours after application of the cream. Eflornithine is only for external use, so avoid contact with eyes, mouth, nose or vaginal area.

Eflornithine has very few effects, such as skin tingling, redness of skin after application, or temporary burning and stinging if the affected area.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Dermatologist before using this medicine.

In addition to its intended effect, Eflornithine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Acne
Erythema
Burning discomfort
Stinging sensation
Dry skin
Rash
Tingling sensation
Irritation
Hair follicle inflammation.
Is It safe with alcohol?
No interaction found
Are there any pregnancy warnings?
Eflora 13.9% cream may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?
Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?
There is no interaction between driving and consuming this drug. So dose alteration is not needed.
Does this affect kidney function?
There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?
There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?
If you miss a dose of Eflornithine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Below is the list of medicines, which contains Eflornithine as ingredient
Sun Pharmaceutical Industries Ltd
Ajanta Pharma Ltd
Zydus Cadila
Eris Life Sciences Pvt Ltd
Eflornithine is used to treat excess facial hair in women and African trypanosomiasis. It acts as a suicide inhibitor for ornithine and prevents the same from accessing the active site.
What are you using Eflornithine for?
facial hirsutism
Other
How much was the improvement?
Excellent
Average
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

Is it good to use eflornithine cream for men? Does it really stops hair on cheeks and under eyes for men?

MS - General Surgery, MCh - Plastic and Reconstructive Surgery
Cosmetic/Plastic Surgeon, Jaipur
Is it good to use eflornithine cream for men? Does it really stops hair on cheeks and under eyes for men?
NO and YES. No it is not a good idea to use in men. But if you want you can surely use it it just keep in mind that 1. Men have much more hair and the effect of cream will not be as good as that in women (it is basically used for women) 2. You will revert to previous state with in 4 months of stopping the treatment. Chances of allergies and acne are more. 3. There are better ways to get rid of extra facial hair like LASER /IPL hair reduction (beard shapping) which is a relatively permanent solution to extra hair on the face.

I am 26 year old male ,I am suffering from hair growth on my cheeks though I had taken laser treatment for 6 sessions but no improvement. What can I do further to stop hair growth on my cheeks?

MD - (Dermatology & STD)
Dermatologist, Bangalore
I am 26 year old male ,I am suffering from hair growth on my cheeks though I had taken laser treatment for 6 sessions...
Eflornithine 13% cream can be used. But results are slow. You can take further sessions of laser rx. Some ppl need longer duration of treatment.
1 person found this helpful

I am 17 years old boy and I have unwanted hairs on my face and few in my nose give me any solution but no laser treatment.

MCh Plastic Surgery, MS - General Surgery
Cosmetic/Plastic Surgeon, Bangalore
I am 17 years old boy and I have unwanted hairs on my face and few in my nose give me any solution but no laser treat...
Hello lybrate-user, Laser is a safe method and gives good results. If you not willing for laser you can use Eflornithine cream which reduces hair growth.

I want hair remove on my forehead for permanently. Give me suitable solutions of these problem.

MCh Plastic Surgery, MS - General Surgery
Cosmetic/Plastic Surgeon, Bangalore
I want hair remove on my forehead for permanently. Give me suitable solutions of these problem.
Hello, Laser hair removal is safe and effective treatment. You will require 6-8sessions with maintainance once 6mo or a yr. Also there are eflornithine based creams which reduce hair growth.

It is my first pregnancy I am 5 month pregnant I want to know that can we use hair removal cream in pregnancy.

MCh Plastic Surgery, MS - General Surgery
Cosmetic/Plastic Surgeon, Bangalore
It is my first pregnancy I am 5 month pregnant I want to know that can we use hair removal cream in pregnancy.
Hello, Eflornithine based creams are not assessed for safety in pregnancy and during breast feeding. It is better to avoid creams during pregnancy. Laser are safe options.

Popular Health Tips

Hirsutism - How Best Can it Be Managed?

MD - Dermatology , Venereology & Leprosy, MBBS
Dermatologist, Delhi
Hirsutism - How Best Can it Be Managed?

Most women love the idea of having healthy and silky skin that feels smooth to touch. However, due to a certain reasons, some women can have excessive, unwanted hair on their chest, hands and face. The pattern is similar to what is seen in men. This can be a major psychological problem. Read on to know more about some of the common reasons for this and how it can be managed:

Common causes behind it
Hair pattern is largely determined by genetic makeup and hirsutism is often caused by genes, hormones, or medication which is another main cause is the excessive amount of testosterone in women. Conditions like obesity, polycystic ovaries disease, ovarian tumours, adrenal tumours, Cushing’s syndrome and drugs like Danazol can cause excessive androgen hormones. Women with this condition may also have a deep voice, huge breasts, enlarged clitoris, severe acne and may also suffer from hair loss. These symptoms are collectively referred to as virilisation.

Ways to control hirsutism
The treatment is aimed at removing the unwanted hair and treating the underlying cause. A combination of medications and procedures can help in removing the excessive hair.

  1. Weight loss: Reducing weight makes the body produce less of the male hormone, and so hirsutism is controlled.
  2. Female hormone replacement: Birth control pills are a good choice for women who do not want to get pregnant. They control the androgen hormone production and reduce hair growth and other characteristics.
  3. Anti-androgens: Spironolactone is an anti-androgen which counters the effect of testosterone; however, these have side effects and self-medication is not advisable.
  4. Topical creams: The face is the major area of concern and so creams like eflornithine are useful to control hair growth on the face.

Procedures

Depending on the patient’s severity of the problem and expectations, the following procedural options are available. While some of these can be done at home, others might require a visit to a doctor.

  1. Shaving: To be done repeated as and when the growth occurs.
  2. Tweezing: Isolated strands of hair can be removed with a tweezer.
  3. Waxing: This is useful in removing hair from large areas (chest, hands, etc.)
  4. Bleaching creams or lotions: The hair stays in place but is lightened in colour to give it a camouflaged appearance.
  5. Depilatory creams, lotions, or gels: These break down the hair follicles and prevent hair growth.
  6. Electrolysis: A small amount of electric current is applied to the hair follicle to destroy it, thereby controlling hair growth.
  7. Laser hair treatment: A small beam of highly concentrated light is applied to the affected area to damage the hair follicles and control hair growth.

Hirsutism is definitely not desirable, but there are definitely ways to manage the problems and get back to having a smooth, silky skin.

If you wish to discuss about any specific problem, you can consult a doctor and ask a free question.

2357 people found this helpful

How To Manage Hirsutism?

MBBS, Diploma in Venerology & Dermatology (DVD), DDV, MD - Dermatology , Venereology & Leprosy
Dermatologist, Pune
How To Manage Hirsutism?

Most women love the idea of having healthy and silky skin that feels smooth to touch. However, due to a certain reasons, some women can have excessive, unwanted hair on their chest, hands and face. The pattern is similar to what is seen in men. This can be a major psychological problem. Read on to know more about some of the common reasons for this and how it can be managed:

Common causes behind it
Hair pattern is largely determined by genetic makeup and hirsutism is often caused by genes, hormones, or medication which is another main cause is the excessive amount of testosterone in women. Conditions like obesitypolycystic ovaries disease, ovarian tumours, adrenal tumours, Cushing’s syndrome and drugs like Danazol can cause excessive androgen hormones. Women with this condition may also have a deep voice, huge breasts, enlarged clitoris, severe acne and may also suffer from hair loss. These symptoms are collectively referred to as virilisation.

Ways to control hirsutism
The treatment is aimed at removing the unwanted hair and treating the underlying cause. A combination of medications and procedures can help in removing the excessive hair.

  1. Weight loss: Reducing weight makes the body produce less of the male hormone, and so hirsutism is controlled.
  2. Female hormone replacement: Birth control pills are a good choice for women who do not want to get pregnant. They control the androgen hormone production and reduce hair growth and other characteristics.
  3. Anti-androgens: Spironolactone is an anti-androgen which counters the effect of testosterone; however, these have side effects and self-medication is not advisable.
  4. Topical creams: The face is the major area of concern and so creams like eflornithine are useful to control hair growth on the face.

Procedures

Depending on the patient’s severity of the problem and expectations, the following procedural options are available. While some of these can be done at home, others might require a visit to a doctor.

  1. Shaving: To be done repeated as and when the growth occurs.
  2. Tweezing: Isolated strands of hair can be removed with a tweezer.
  3. Waxing: This is useful in removing hair from large areas (chest, hands, etc.)
  4. Bleaching creams or lotions: The hair stays in place but is lightened in colour to give it a camouflaged appearance.
  5. Depilatory creams, lotions, or gels: These break down the hair follicles and prevent hair growth.
  6. Electrolysis: A small amount of electric current is applied to the hair follicle to destroy it, thereby controlling hair growth.
  7. Laser hair treatment: A small beam of highly concentrated light is applied to the affected area to damage the hair follicles and control hair growth.

Hirsutism is definitely not desirable, but there are definitely ways to manage the problems and get back to having a smooth, silky skin.

In case you have a concern or query you can always consult an expert & get answers to your questions!

4798 people found this helpful

Causes, Symptoms And Treatment Of Razor Bumps

MBBS, Diploma in Venerology & Dermatology (DVD), DDV, MD - Dermatology , Venereology & Leprosy
Dermatologist, Pune
Causes, Symptoms And Treatment Of Razor Bumps

What is Razor Bump (Pseudofolliculitis Barbae)?

It is an inflammatory reaction to the hair shaft entering the skin, most common in blacks who shave regularly.

Who gets razor bumps?

About 50% of black males are said to be affected. Other races can also be affected. Though the condition is most commonly reported in men, women who remove unwanted hair also suffer from this condition.

Causes of Razor Bumps-

The condition is caused by both genetic factors and various hair removal methods.

Genetic factors:

  1. Curved hair follicles and curly hair
  2. A defect in the gene for the hair protein keratin 6hf

Hair removal methods may cause razor bumps by either creating a sharp hair tip that re-enters the skin away from the hair pore (extrafollicular penetration) or by the hair shaft breaking off at different lengths and piercing the follicle from within the skin (transfollicular penetration). An inflammatory reaction is then set up in response to the hair fragments lying in the skin. The following methods may cause razor bumps:

  1. Shaving
  2. Tweezing
  3. Waxing
  4. Electrolysis

Symptoms-

  • Ingrown hairs
  • Red, skin coloured or dark bumps
  • Bumps containing pus

What are the complications of razor bumps?

  • Pigmentary problems (darkening of the area most common)
  • Scarring
  • Abscess formation
  • Psychological problems

Razor bumps are most common on the beard, however they have been reported to occur on the pubic area, legs and scalp.

The Treatment-

There are several treatment options to deal with razor bumps already present. They include:

  • Moisturizers
  • Retinoids
  • Steroids
  • Antibiotics
  • Alpha-hydroxy acids
  • Chemical peels
  • Microdermabrasion

Prevention of Razor Bumps:

It is true to say that 'prevention is better than cure'. Here are the preventions-

  • Laser hair removal is the best method of removing unwanted hair in individuals affected with this condition. The laser device is programmed to selectively target the pigment in the hair follicle, destroying it, while leaving the skin intact.
  • Electrical clippers are found by many to cause less bumps than razors. If one must shave it is important to avoid a close shave to help prevent razor bumps. The following is a guide to safer shaving methods:
    • Brush hairs with polyester sponge before shaving.
    • Wash beard, use pre-shave cream or gel.
    • Avoid double and triple blade razors.
    • Shave in the direction of hair growth.
    • Do not pull the skin taut.
    • Use a sharp blade, rinse after each stroke.
    • Apply a cold compress after shaving, then a soothing aftershave preparation.
  • Clipping hairs with a small pair of facial scissors is an option for women with few unwanted hairs.
  • Chemical depilatories (hair removal creams) are another option for hair removal.
  • Electrolysis is a permanent method of hair removal but requires several sessions. It is operator dependent and can cause bumps and scarring. Waxing and tweezing also have the potential to cause bumps.
  • Eflornithine hydrochloride is a cream that slows the growth of hair and therefore can be used in combination with a hair removal method. It is marketed for women with unwanted facial hair.
  • Anti-androgen drugs can be used in females who have hirsutism (male pattern hair growth e.g. beard hairs)

In case you have a concern or query you can always consult an expert & get answers to your questions!

6588 people found this helpful

Razor Bumps - Causes, Treatment and Prevention

MBBS, MD - Dermatology
Dermatologist, Delhi
Razor Bumps - Causes, Treatment and Prevention

What is Razor Bump (Pseudofolliculitis Barbae)?

It is an inflammatory reaction to the hair shaft entering the skin, most common in blacks who shave regularly.

Who gets razor bumps?

About 50% of black males are said to be affected. Other races can also be affected. Though the condition is most commonly reported in men, women who remove unwanted hair also suffer from this condition.

Causes of Razor Bumps-

The condition is caused by both genetic factors and various hair removal methods.

Genetic factors:

  1. Curved hair follicles and curly hair
  2. A defect in the gene for the hair protein keratin 6hf

Hair removal methods may cause razor bumps by either creating a sharp hair tip that re-enters the skin away from the hair pore (extrafollicular penetration) or by the hair shaft breaking off at different lengths and piercing the follicle from within the skin (transfollicular penetration). An inflammatory reaction is then set up in response to the hair fragments lying in the skin. The following methods may cause razor bumps:

  1. Shaving
  2. Tweezing
  3. Waxing
  4. Electrolysis

Symptoms-

  • Ingrown hairs
  • Red, skin coloured or dark bumps
  • Bumps containing pus

What are the complications of razor bumps?

  • Pigmentary problems (darkening of the area most common)
  • Scarring
  • Abscess formation
  • Psychological problems

Razor bumps are most common on the beard, however they have been reported to occur on the pubic area, legs and scalp.

The Treatment-

There are several treatment options to deal with razor bumps already present. They include:

  • Moisturizers
  • Retinoids
  • Steroids
  • Antibiotics
  • Alpha-hydroxy acids
  • Chemical peels
  • Microdermabrasion

Prevention of Razor Bumps:

It is true to say that 'prevention is better than cure'. Here are the preventions-

  • Laser hair removal is the best method of removing unwanted hair in individuals affected with this condition. The laser device is programmed to selectively target the pigment in the hair follicle, destroying it, while leaving the skin intact.
  • Electrical clippers are found by many to cause less bumps than razors. If one must shave it is important to avoid a close shave to help prevent razor bumps. The following is a guide to safer shaving methods:
    • Brush hairs with polyester sponge before shaving.
    • Wash beard, use pre-shave cream or gel.
    • Avoid double and triple blade razors.
    • Shave in the direction of hair growth.
    • Do not pull the skin taut.
    • Use a sharp blade, rinse after each stroke.
    • Apply a cold compress after shaving, then a soothing aftershave preparation.
  • Clipping hairs with a small pair of facial scissors is an option for women with few unwanted hairs.
  • Chemical depilatories (hair removal creams) are another option for hair removal.
  • Electrolysis is a permanent method of hair removal but requires several sessions. It is operator dependent and can cause bumps and scarring. Waxing and tweezing also have the potential to cause bumps.
  • Eflornithine hydrochloride is a cream that slows the growth of hair and therefore can be used in combination with a hair removal method. It is marketed for women with unwanted facial hair.
  • Anti-androgen drugs can be used in females who have hirsutism (male pattern hair growth e.g. beard hairs)
4221 people found this helpful

Razor Bumps - Why Do They Occur?

MBBS, DNB(Skin & VD)
Dermatologist, Gurgaon
Razor Bumps - Why Do They Occur?

It is an inflammatory reaction to the hair shaft entering the skin, most common in blacks who shave regularly.

Who gets razor bumps?

About 50% of black males are said to be affected. Other races can also be affected. Though the condition is most commonly reported in men, women who remove unwanted hair also suffer from this condition.

Causes of Razor Bumps-

The condition is caused by both genetic factors and various hair removal methods.

Genetic factors:

  1. Curved hair follicles and curly hair
  2. A defect in the gene for the hair protein keratin 6hf

Hair removal methods may cause razor bumps by either creating a sharp hair tip that re-enters the skin away from the hair pore (extrafollicular penetration) or by the hair shaft breaking off at different lengths and piercing the follicle from within the skin (transfollicular penetration). An inflammatory reaction is then set up in response to the hair fragments lying in the skin. The following methods may cause razor bumps:

  1. Shaving
  2. Tweezing
  3. Waxing
  4. Electrolysis

Symptoms-

  • Ingrown hairs
  • Red, skin coloured or dark bumps
  • Bumps containing pus

What are the complications of razor bumps?

  • Pigmentary problems (darkening of the area most common)
  • Scarring
  • Abscess formation
  • Psychological problems

Razor bumps are most common on the beard, however they have been reported to occur on the pubic area, legs and scalp.

The Treatment-

There are several treatment options to deal with razor bumps already present. They include:

  • Moisturizers
  • Retinoids
  • Steroids
  • Antibiotics
  • Alpha-hydroxy acids
  • Chemical peels
  • Microdermabrasion

Prevention of Razor Bumps:

It is true to say that 'prevention is better than cure'. Here are the preventions-

  • Laser hair removal is the best method of removing unwanted hair in individuals affected with this condition. The laser device is programmed to selectively target the pigment in the hair follicle, destroying it, while leaving the skin intact.
  • Electrical clippers are found by many to cause less bumps than razors. If one must shave it is important to avoid a close shave to help prevent razor bumps. The following is a guide to safer shaving methods:
    • Brush hairs with polyester sponge before shaving.
    • Wash beard, use pre-shave cream or gel.
    • Avoid double and triple blade razors.
    • Shave in the direction of hair growth.
    • Do not pull the skin taut.
    • Use a sharp blade, rinse after each stroke.
    • Apply a cold compress after shaving, then a soothing aftershave preparation.
  • Clipping hairs with a small pair of facial scissors is an option for women with few unwanted hairs.
  • Chemical depilatories (hair removal creams) are another option for hair removal.
  • Electrolysis is a permanent method of hair removal but requires several sessions. It is operator dependent and can cause bumps and scarring. Waxing and tweezing also have the potential to cause bumps.
  • Eflornithine hydrochloride is a cream that slows the growth of hair and therefore can be used in combination with a hair removal method. It is marketed for women with unwanted facial hair.
  • Anti-androgen drugs can be used in females who have hirsutism (male pattern hair growth e.g. beard hair). Consult an Expert & get answers to your questions!
2439 people found this helpful

Table of Content

About Eflornithine
What are the side effects of Eflornithine ?
Key highlights of Eflornithine
What are the dosage instructions?
Medicines containing Eflornithine