Cremagel 2% Gel

This medication obstructs calcium to function and effectively relax muscles and blood vessels. The drug is prescribed to patients who suffer from Piles, Anal ulcer, Anal irritation and Chronic anal fissures. The medicine is applied rectally and the dosage should be strictly taken according to the prescription.

This medication can cause certain side effects, which may aggravate if the dosage is not right. Some side effects of this gel are-

• Light headedness
• Perianal dermatitis
• Nausea and weakness
• Dark urine and stool
• Pain in the stomach
• Rashes
• Sore throat and fever

The medicine is generally not prescribed to patients with severe heart problems and suffer from hypotension. It is also not recommended for patients who have had a heart attack very recently. Doctors should be informed about any kidney problems, liver disease or allergies to make sure that the drug is safe for consumption.

• Piles

• Chronic Anal Fissures

• Anal Ulcer

• Anal Irritation

• Allergy

• Hypotension

• Acute myocardial infarction

• Sick Sinus Syndrome

• Fever

• Headache

• Sneezing

• Muscle Pain

• Skin Rash

• How long is the duration of effect?

  The effect of this medicine lasts for an average duration of 9 to 12 hours.

• What is the onset of action?

  The peak effect of this medicine can be observed in 2 to 4 hours after the dose administration.

• Are there any pregnancy warnings?

  This medicine is not recommended for pregnant women. Use under the supervision of the doctor, only if clinical condition clearly requires the use of this medicine.

• Is it habit forming?

  No habit forming tendencies were reported.

• Are there any breast-feeding warnings?

  This medicine is not recommended for breastfeeding women. Use only if clearly needed under the doctor's supervision. Monitoring of blood pressure is necessary.

Below is the list of medicines, which have the same composition, strength and form as Cremagel 2% Gel , and hence can be used as its substitute.

• Dilzem 2% Gel

  Torrent Pharmaceuticals Ltd

• Diltiact 2% Gel

  Sun Pharma Laboratories Ltd

• Missed Dose instructions

  The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for your next dose.

• Are there any overdose instructions?

  Seek emergency medical treatment or contact the doctor in case of an overdose.

This medication belongs to the class non-dihydropyridine calcium-channel blocker. It works by inhibiting the influx of calcium into the myocardial cells and vascular smooth muscle cells thus inhibit the contraction of muscles and dilate the coronary and smooth muscle arteries.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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• Interaction with Alcohol

  Alcohol

  Consumption of alcohol should be avoided while taking this medicine, especially when you start taking the medicine or a change its dosage. Symptoms like headache, dizziness, change in pulse or heart rate should be reported to the doctor.

• Interaction with Lab Test

  Lab

  Information not available.

• Interaction with Medicine

  Carbamazepine

  Combined use of these medicines is not recommended due to changes in the levels of these medicines. Any symptoms of headache, dizziness, visual disturbances should be reported to the doctor. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.

  Itraconazole

  Combined use of these medicines is not recommended due to changes in the levels of this medication. Any symptoms of swelling of hands, feet, dizziness should be reported to the doctor. Avoid operating machinery and driving vehicle. Dose adjustments are to be made based on the clinical condition or an alternate medicine should be considered.

  Ethinyl Estradiol

  The blood levels of oral contraceptives may increase if taken with this medication. Dose adjustments are to be based on the clinical condition or an alternate medicine should be considered.

  Atorvastatin

  These medicines should be used with caution due to increase in the levels of atorvastatin which may cause severe muscle injury. Frequent monitoring of kidney function tests is necessary. Any symptoms of muscle pain, tenderness, dark colored urine should be reported to the doctor. Dose adjustments or an alternate medicine should be considered based on the clinical condition.

• Interaction with Disease

  Aortic Stenosis

  This medication is not recommended in the patients with aortic stenosis as it may worsen the myocardial oxygen balance.

• Interaction with Food

  Food

  Information not available.

• Diltiazem- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2019 [Cited 23 May 2019]. Available from:

  https://druginfo.nlm.nih.gov/drugportal/name/diltiazem

• Diltiazem- DrugBank [Internet]. Drugbank.ca. 2019 [Cited 23 May 2019]. Available from:

  https://www.drugbank.ca/drugs/DB00343

• Important Information About Diltiazem- Drugs Bank [Internet]. drugsbanks.com. 2017 [Cited 23 May 2019]. Available from:

  https://www.drugsbanks.com/important-information-about-diltiazem/