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Overview

Azicip 250 MG Tablet

Azicip 250 MG Tablet

Manufacturer: Cipla Ltd
Medicine composition: Azithromycin
Prescription vs.OTC: Prescription by Doctor required

Azicip 250 MG Tablet belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections, traveler's diarrhea. Along with other medications, it is sometimes used for malaria. It is also used to treat a number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia. Administration of the medicine takes place either by mouth or intravenously with doses once per day.

You should not use Azicip 250 MG Tablet without consulting a doctor if you :

  • have suffered from allergy, jaundice or other liver problems caused by taking azithromycin or other similar drugs such as clarithromycin and erythromycin sometime in the past; or
  • have myasthenia gravis, a heart rhythm disorder or a history of long QT syndrome(Long QT syndrome refers to a heart rhythm disorder that can potentially cause rapid heartbeats, irregular heart rhythms and even dealth).
  • Few common side effects of this medicine include nausea, vomiting, stomach upset and diarrhoea. An allergic reaction can be caused by Clostridium difficile. It?s usage is mostly considered to be safe even during pregnancy and breastfeeding. Azicip 250 MG Tablet is an azalide so it works by putting an end to bacterial growth by cutting down protein synthesis entirely.

    Your dosage and how often you take the medicine will depend on your age, the condition being treated and its severity, other medical conditions and how you react to the first doze. Azicip 250 MG Tablet is a prescription drug and its available as an oral tablet, oral suspension, eye drop, intravenous form that a healthcare provider cam give. Treatment from Azicip 250 MG Tablet is short term and it becomes very risky if not taken as prescribed.

Community acquired pneumonia
Azicip 250 MG Tablet is used to treat community-acquired Pneumonia which is the most common type of Pneumonia. The most common symptoms include cough, fever with chills and difficulty in breathing.
Ear Infection (Otitis Media)
Azicip 250 MG Tablet is used to treat Otitis Media which is an ear infection. The most common symptoms include headache, ear pain, ringing ear and loss of balance.
Pharyngitis/Tonsillitis
Azicip 250 MG Tablet is used to treat sore throat or Pharyngitis (an inflammation of the throat caused by bacteria or smoking). The most common symptoms include cough, running nose, difficulty in swallowing and fever with chills.
Skin and soft tissue infections
Azicip 250 MG Tablet is used to treat skin and soft tissue infections caused by bacteria. Fever with chills, redness around hair follicles, yellowish rash and muscle pain are the most common symptoms.
Hypersensitivity
Avoid, if you have a known allergy to Azicip 250 MG Tablet.
Liver damage
Avoid, if you are suffering from any liver disease.
In addition to its intended effect, Azicip 250 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Diarrhea Major Common
Contact your doctor if you have this symptom
Dry or scaly skin Major Less Common
Contact your doctor if you have this symptom
Abdominal Pain Major Less Common
Contact your doctor if you have this symptom
Difficult or painful urination Major Rare
Contact your doctor if you have this symptom
Vomiting Major Rare
Contact your doctor if you have this symptom
Fever Major Rare
Contact your doctor if you have this symptom
Acid or sour stomach Minor Rare
Contact your doctor if you have this symptom
Aggression or anger Minor Rare
Contact your doctor if you have this symptom
Excessive air or gas in stomach Minor Rare
Contact your doctor if you have this symptom
Heartburn Minor Rare
Contact your doctor if you have this symptom
How long is the duration of effect?
The effect of this medicine lasts for an average duration of 2 to 4 days.
What is the onset of action?
The effect of this medicine can be observed within 2 to 3 hours of dose administration.
Are there any pregnancy warnings?
Use of this medicine is not recommended in pregnant women.
Is it habit forming?
No habit forming tendency has been reported.
Are there any breast-feeding warnings?
As low levels of this medicine is excreted through human breast milk monitoring of possible side effects like Diarrhoea, Candidiasis is necessary.
Below is the list of medicines, which have the same composition, strength and form as Azicip 250 MG Tablet, and hence can be used as its substitute.
Agron Remedies Pvt. Ltd
Wockhardt Ltd
Lupin Ltd
Orchid Chemicals & Pharmaceuticals Ltd
Agron Remedies Pvt. Ltd
Missed Dose instructions
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
Overdose instructions
Seek emergency medical attention or contact your doctor in case of over dose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
QT Prolongation Major
Inform your doctor if you have arrhythmia, any heart disease or drugs that prolong QT interval such as psychiatric drugs, anti-arrhythmic drugs.
Liver Disease Moderate
Inform your doctor if you have any liver disease and drugs that cause liver damage (Eg: TB drugs, HIV drugs).
Myasthenia Gravis Moderate
Inform your doctor if you are suffering from thyroid disease or Myasthenia Gravis (Double vision, drooping of eyelids, difficulty in swallowing, unsteady walk). You are also at risk if you are taking any medicines that cause Myasthenia Gravis (Eg: D-Penicillamine, Fluoroquinolones etc).
Interaction with Alcohol
Alcohol
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Atorvastatin Moderate
Contact your doctor if you have dark colored urine, muscle pain, tenderness, or weakness.
Amiodarone Major
Contact your doctor if you have lightheadedness, fainting, shortness of breath. Usage of other medicines should be reported to the doctor.
Pimozide Major
Contact your doctor if you notice irregular heartbeat, nausea, tightness in the chest or blurred vision. Also, inform your doctor about all your medications.
Aluminium Hydroxide/Magnesium Hydroxide Moderate
Take Azicip 250 MG Tablet at least 1 hour before or 2 hours after Azicip 250 MG Tablet. Usage of other medicines should be reported to the doctor.

Popular Questions & Answers

Hello respected doctors .My sis is having cold cough and fever since 7 days .Since 6 Days she's taking azicip 500 mg one tablet for 3 days ,reaction plus 2 tablets in a day for 4 days as per doctors prescription .But still cough cold and fever haven't reduced .could you please help?

MBBS
General Physician, Mumbai
Hello respected doctors .My sis is having cold cough and fever since 7 days .Since 6 Days she's taking azicip 500 mg ...
Dear lybrateuser, -Do steam inhalation three times a day -take tablet Sinarest, 1 tablet three times a day after food with water or milk -avoid cold fluids, have more of warm fluids like water, tea, coffee, milk (mix 1/4 teaspoon of turmeric in 1 cup of milk, have twice a day) & warm soup -avoid sour, fried & spicy food -do warm salt water gargles three times a day if itching or pain in throat -if still not much relief then do blood cbc, x-ray chest & consult a doctor you may require a change in medication or new medication. -

Two days ago. While doing chemistry experiment may be I have doubt that I swallowed very minute amount of benzene but I am not sure. Ii i swallowed my saliva or benzene Layer so, please advice how i should assure myself. I have also. Small fever from two days. This is due to viral infection or due to benzene.

MBBS
General Physician,
Two days ago. While doing chemistry experiment may be I have doubt that I swallowed very minute amount of benzene but...
Hello, Thanks for your query on Lybrate "As"per your clinical history is concerned your fever is due to infection only because by ingestion of benzene dose not cause fever and you will get other symptoms, so do a CBC with differential to know whether infection is viral or bacterial. If infection is bacterial then take [paracetamol] for fever and [Azithromycin].for infection. Hope that helps

Dear sir, I have a problem in my eyes. I have dandruff on my Eyelash. How to remove it .please help me. Thank you and waiting your reply.

Fellowship in Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
Dear sir, I have a problem in my eyes.
I have dandruff on my Eyelash. How to remove it .please help me. Thank you and...
Hello A. Warm compresses B. Scrub lashes with baby shampoo C. Apply antibiotic ointment like azithromycin locally over lid margins

Doctor sahab, mere cough jadya rehta h kya krna chahhiye cold hone pr cough banta h.

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
Tab. Azithromycin 500 mg one daily for five days and Tab Lacto-LM od for 10 days and do saline gargles. Do Allergy test.

Popular Health Tips

Gonorrhea - How It Is Affecting Your Sexual Life?

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Sexologist, Allahabad
Gonorrhea - How It Is Affecting Your Sexual Life?

Gonorrhoea is transmitted infection caused when people come in a physically intimate contact. It can affect both male and female. The most vulnerable organs that are susceptible to gonorrhoea infection include rectum, urethra, and throat. In females, gonorrhoea might affect the cervix as well. Since the infection spreads from having sex, there are wide chances that the baby gets affected too. Although there could be no visible symptoms of gonorrhoea, early detection and treatment increase the chances of a permanent cure.

How does gonorrhoea affect the sexual life?
Once a person gets affected, gonorrhoea may wreak havoc on the sex life of both a male and female. In males, there could be swelling and pain in one testicle leading to difficulty in having sex. Additionally, urination after sex becomes painful. There could be a pus-like discharge from the penis thereby completely obstructing the chances of sex.

In females, there could be abdominal pain during the intercourse. Intercourse itself could be extremely painful. Apart from this, the urination after sex could be very painful. Additionally, there are chances of vaginal discharge after sex. There are high chances of vaginal bleeding after sex followed by itching of the anus. If the bacteria are very active, lymph nodes of the throat getting swollen after oral sex.

The treatment plan for gonorrhoea in adults

  1. Adults infected with the gonorrhoea bacteria are treated with antibiotics. Since gonorrhoea bacteria are increasingly becoming drug-resistant, doctors treat the patient with an antibiotic known as Ceftriaxone in the form of injection.
  2. In addition to this, two antibiotics that are prescribed to be taken in the oral form include Doxycycline and Azithromycin. There are some studies which revealed that injectable Gentamicin along with oral Azithromycin is a successful combination that can treat gonorrhoea. Furthermore, this combination proves to be highly successful in treating patients who are allergic to cephalosporin-based antibiotics.
  3. In addition to the treatment of the infected patient, the partner should also be thoroughly checked for symptoms of gonorrhoea treatment even if there exist no symptoms of the disease as such. There is a high likelihood of one partner getting infected in case the other one is infected.
  4. If a baby gets infected with gonorrhoea in the womb, he/she should get immediate eye medication to ensure that there no loss of vision when he/she is born. Babies should also get a dosage of antibiotics.
  5. Some basic hygiene such as not having sex during the course of the treatment, use of protection during sex, avoiding oral sex, avoiding sex with multiple partners etc. should be followed.

Regular consultation with the doctor is necessary till the condition gets cured for good.

Typhoid - Signs You Are Suffering From It!

MBBS, Diploma in Tuberculosis and Chest Diseases (DTCD), MD - General Medicine
General Physician, Delhi
Typhoid - Signs You Are Suffering From It!

Typhoid is as an acute illness commonly characterized by high fever and an impaired digestive system. This illness is caused by the bacterium ‘Salmonella Typhi’ and generally spreads from one person to another by means of food or water.

Causes of typhoid

  • Salmonella Typhi, the bacterium responsible for typhoid, primarily spreads on consumption of unhygienic street food and water.
  • Typhoid can also occur as a result of a poor sanitation system. In these cases, the bacterium spreads through fecal matters and the contaminated urine of the infected person.
  • Typhoid can also spread if you share the same food and water consumed by the infected person.

Symptoms 
The symptoms generally appear within 1-3 weeks, after coming in contact with the already infected individual. The ensuing fever and discomfort remains for about 3-4 weeks. The symptoms are:

  • Severe headache and loss of appetite
  • High fever
  • Severe discomfort in the whole body coupled with pain in the abdomen area
  • Drowsiness
  • Diarrhea or constipation
  • A dry cough and appearance of rashes

However, in most of the cases, the symptoms tend to improve from the third week itself.

Treatment
The following treatments can be implemented in order to cure typhoid fever:

  • Doctors generally recommend a prescribed dosage of antibiotics in order to deal with the disease. 
  • Along with the prescribed dosage of antibiotics, the doctors recommend balanced consumption of various fluids such as natural fruit juices and water to restore hydration. A healthy diet packed with all the essential nutrients is another necessity that has to complement the dosage of antibiotics.
  • Choice of antibiotics should be Ceftriaxone, Cefixime, Azithromycin and Ciprofloxacin.

Complications

  1. The two most common complications are haemorrhage (including disseminated intravascular coagulation) and perforation of the bowel. Before antibiotics, perforation had a mortality of around 75%.
  2. Jaundice may be due to hepatitis, cholangitis, cholecystitis, or haemolysis.
  3. Pancreatitis with acute kidney injury and hepatitis with hepatomegaly are rare.
  4. Toxic myocarditis occurs in 1-5% of patients (ECG changes may be present). It is a significant cause of death in endemic areas.
  5. Toxic confusional states and other neurological and psychiatric disturbances have been reported.

Needs and Indications for Hospitalization-

Hospital admission is usually recommended if you have severe symptoms of typhoid fever, such as persistent vomiting, severe diarrhoea or a swollen stomach. As a precaution, young children who develop typhoid fever may be admitted to hospital. In hospital, you'll have antibiotic injections and you may also be given fluids and nutrients directly into a vein through an intravenous drip. Surgery may be needed if you develop life-threatening complications of typhoid fever, such as internal bleeding or a section of your digestive system splitting. However, this is very rare in people being treated with antibiotics. Most people respond well to hospital treatment and improve within three to five days. However, it may be several weeks until you're well enough to leave hospital.

Vaccines

Two types of vaccines are available

  • Injected
  • Oral 

The injected vaccine is more commonly used and  is also known as inactivated typhoid shot . It is injected in one single shot an it can easily provide protection against typhoid. This type is widely prevalent in cases where one has to travel to a typhoid infected place. However, one must be careful and should keep a tab as to what they eat or drink at the time of travelling. Also, this type of vaccine should not be administered on kids below 2 years old.

If you wish to discuss about any specific problem, you can consult a doctor.

6982 people found this helpful

All About Typhoid Fever!

MBBS
General Physician, Chittorgarh

What is typhoid fever?
Typhoid fever or enteric fever is a digestive tract infection in which there is fever, headache, and abdominal pain or discomfort. It is very common in developing countries like india.

What are the causes and risk factors?
Typhoid fever is caused by a bacterium called salmonella typhi which is transmitted through contaminated water or food (feco-oral or urine-oral route).

Risk factors include:

  • Travelling to areas where typhoid fever is a common disease.
  • Being in a profession where contamination with bacteria is likely. Like those working in laboratories.
  • Coming in close contact with a person suffering from typhoid.
  • Drinking/ eating contaminated water or food.

How will you know if you have typhoid fever?
Signs and symptoms develop gradually over the period of 10-14 days after exposure to the bacteria.
Signs and symptoms include an irregular fever that can go up to 104.9 ?f (40.5 ?c), headache, pain in abdomen, tiredness, muscle pain, loss of appetite, nausea, constipation or diarrhoea, skin rash.

How is typhoid fever diagnosed?
Your doctor will do a physical examination and carry out some tests.
Physical findings in early stages include abdominal tenderness, enlarged spleen and liver, enlarged lymph nodes, and development of a rash (also known as rose spots because of their appearance).

Investigations include:

  • Blood tests: typhidot test igm and igg antibodies, blood culture to test for salmonella typhi.
  • Stool and urine analysis
  • Bone marrow culture: it is the most sensitive test, but it is rarely required except in patients who have already received antibiotics and not getting any better.
  • Widal antigen test: this test can be done, but there is a longer waiting phase of about 10 days till results can be seen, it is time-consuming and could give false positive results.

What is the treatment for typhoid fever?

  • Antibiotics are the only effective treatment option for typhoid fever.
  • Due to increased resistance to ciprofloxacin the new drugs of choice are azithromycin and ceftriaxone.
  • In some cases, chloramphenicol, co-trimoxazole and amoxicillin may also be effective.
  • Fluid intake should be increased to prevent dehydration.

What are the complications of typhoid fever?
If not treated and sometimes even after treatment, there can be serious complications due to typhoid like pneumonia, meningitis (inflammation of meninges of brain), infection in bones (osteomyelitis), intestinal perforation and intestinal haemorrhage.

A doctor needs to be consulted if a person starts developing the symptoms few days after travelling to a place where typhoid is prevalent.

How can typhoid fever be prevented?

  • Typhoid fever can be prevented by improving sanitation facilities and drinking clean drinking water.
  • Always wash your hands with soap and warm water after using restrooms, before eating or cooking food.
  • Maintaining optimum personal hygiene is the key to preventing this disease.
  • Travellers should not drink untreated water; avoid adding ice to their drinks and should not eat ice creams or milk products or street foods that are a rich source of the infection.
  • Vaccines are available that give partial protection. Vaccines usually are reserved for those who may be exposed to the disease or are travelling to areas where typhoid fever is common.
8 people found this helpful

Mycobacterium Avium Complex

MBBS, D.P.H
General Physician, Gurgaon
Mycobacterium Avium Complex

MYCOBACTERIUM AVIUM COMPLEX

  • Caused by Bacteria M. avium "M.A.C." / M. intrracelulare "M.A.I"

  • MAC is a AIDS-defining condition.
  • MAC is common in persons having CD4 count <50 cell/mm.
  • Respiratory symptoms are not common in HIV -related MAC.
  • Mycobacterium avium complex or M. kansasii  dessiminated  or extramulmonary, almost any internal organ especially the Liver, Spleen, and Bone marrow
  • SYMPTOMS

  •  Night sweats

  • Fever
  • Weight loss
  • Diarrhoea
  • Low level of red and white blood cells.
  • High blood level of liver enzyme ( alkaline phosphatase)
  • Painful intestines.
  • Almost half of those with late -stage HIV disease (AIDS) are infected with the MAC bacteria, not all of those show symptoms of MAC.
  • Elevated alkaline phosphatase levels in blood tests can indicate MAC.
  • TREATMENT:

  • As advised by consulting physician  ( Clarithomycin, Azithromycin, Etambutol , Rifampin, Rifabutin, Ciprofloxacin, Amikacin

5 people found this helpful

Sinusitis: Management and Prevention

MBBS, Fellowship In Endocrinology
Endocrinologist, Tumkur
Sinusitis: Management and Prevention

Sinusitis: Management and Prevention

Sinusitis is infl ammation of the mucous membranes lining one or more of the paranasal sinuses. The various presentations are as folllows:
? acute sinusitis: infection lasting less than 30 days, with complete resolution of symptoms
? subacute infection: lasts from 30 to 90 days, with complete resolution of symptoms
? recurrent acute infection: episodes of acute infection lasting less than 30 days, with resolution of symptoms, which

Recur at intervals of at least 10 days apart
? chronic sinusitis: infl ammation lasting more than 90 days, with persistent upper respiratory symptoms
? acute bacterial sinusitis superimposed on chronic sinusitis:

New symptoms that occur in patients with residual symptoms from prior infection (s). With treatment, the new symptoms resolve but the residual ones do not.
Physical findings and clinical presentation
? patients often give a history of a recent upper respiratory illness with some improvement, then a relapse.
? mucopurulent secretions in the nasal passage
? purulent nasal and postnasal discharge lasting more than 7 to 10 days
? facial tightness, pressure, or pain
? nasal obstruction
? headache
? decreased sense of smell
? purulent pharyngeal secretions, brought up with cough, often worse at night
? erythema, swelling, and tenderness over the infected sinus&nbsp;in a small proportion of patients
? diagnosis cannot be excluded by the absence of such findings.
? these fi ndings are not common, and do not correlate with number of positive sinus aspirates.
? intermittent low-grade fever in about one half of adults with acute bacterial sinusitis
? toothache is a common complaint when the maxillary sinus is involved.
? periorbital cellulitis and excessive tearing with ethmoid sinusitis
? orbital extension of infection: chemosis, proptosis, impaired extraocular movements.

Characteristics of acute sinusitis in children with upper respiratory tract infections:
? persistence of symptoms
? cough
? bad breath
? symptoms of chronic sinusitis (may or may not be present)
? nasal or postnasal discharge
? fever
? facial pain or pressure
? headache
? nosocomial sinusitis is typically seen in patients with nasogastric tubes or nasotracheal intubation.

Cause
? each of the four paranasal sinuses is connected to the nasal cavity by narrow tubes (ostia), 1 to 3 mm in diameter; these drain directly into the nose through the turbinates. The sinuses are lined with a ciliated mucous membrane (mucoperiosteum).
? acute viral infection
? infection with the common cold or infl uenza
? mucosal edema and sinus infl ammation
? decreased drainage of thick secretions, obstruction of the sinus ostia
? subsequent entrapment of bacteria

A. Multiplication of bacteria
B. Secondary bacterial infection

Other predisposing factors
? tumors
? polyps
? foreign bodies
? congenital choanal atresia
? other entities that cause obstruction of sinus drainage
? allergies
? asthma
? dental infections lead to maxillary sinusitis.
? viruses recovered alone or in combination with bacteria (in 16% of cases):
? rhinovirus
? coronavirus
? adenovirus
? parainfluenza virus
? respiratory syncytial virus
? the principal bacterial pathogens in sinusitis are streptococcus pneumoniae, nontypeable haemophilus influenzae, and moraxella catarrhalis.
? in the remainder of cases, fi ndings include streptococcus pyogenes, staphylococcus aureus, alpha-hemolytic streptococci, and mixed anaerobic infections (peptostreptococcus, fusobacterium, bacteroides, prevotella).

Infection is polymicrobial in about one third of cases.
? anaerobic infections seen more often in cases of chronic sinusitis and in cases associated with dental infection; anaerobes are unlikely pathogens in sinusitis in children.
? fungal pathogens are isolated with increasing frequency in immunocompromised patients but remain uncommon
Pathogens in the paranasal sinuses. Fungal pathogens include aspergillus, pseudallescheria, sporothrix, phaeohyphomycoses, zygomycetes.
? nosocomial infections occur in patients with nasogastric tubes, nasotracheal intubation, cystic fi brosis, or those who are immunocompromised.
? s. Aureus
? pseudomonas aeruginosa
? klebsiella pneumoniae
? enterobacter spp.
? proteus mirabilis

Organisms typically isolated in chronic sinusitis:
? s. Aureus
? s. Pneumoniae
? h. Infl uenzae
? p. Aeruginosa
? anaerobes

Differential diagnosis
? migraine headache
? cluster headache
? dental infection
? trigeminal neuralgia

Workup
? water’s projection: sinus radiograph
? ct scan
? much more sensitive than plain radiographs in detecting acute changes and disease in the sinuses
? recommended for patients requiring surgical intervention, including sinus aspiration; it is a useful adjunct to
 

Guide therapy:
? transillumination
? used for diagnosis of frontal and maxillary sinusitis
? place transilluminator in the mouth or against cheek to assess maxillary sinuses, and under the medial aspect of the supraorbital ridge to assess frontal sinuses.
? absence of light transmission indicates that sinus is filled with fluid.
? dullness (decreased light transmission) is less helpful in diagnosing infection.
? endoscopy
? used to visualize secretions coming from the ostia of infected sinuses
? culture collection via endoscopy often contaminated by nasal flora; not nearly as good as sinus puncture
? sinus puncture
? gold standard for collecting sinus cultures
? generally reserved for treatment failures, suspected intracranial extension, nosocomial sinusitis.

Treatment Nonpharmacologic therapy
? sinus drainage
? nasal vasoconstrictors, such as phenylephrine nose drops, 0.25% or 0.5%

? topical decongestants should not be used for more than a few days because of the risk of rebound congestion.
? systemic decongestants
? nasal or systemic corticosteroids, such as nasal beclomethasone, short-course oral prednisone
? nasal irrigation, with hypertonic or normal saline (saline may act as a mild vasoconstrictor of nasal blood fl ow)
? use of antihistamines has no proved benefi t, and the drying effect on the mucous membranes may cause crusting,

Which blocks the ostia, thus interfering with sinus drainage.
? analgesics, antipyretics.

Antimicrobial therapy
? most cases of acute sinusitis have a viral cause and will resolve within 2 weeks without antibiotics.
? current treatment recommendations favor symptomatic treatment for those with mild symptoms.
? antibiotics should be reserved for those with moderate to severe symptoms who meet the criteria for diagnosis of

Bacterial sinusitis.

? antibiotic therapy is usually empirical, targeting the common pathogens.
? first-line antibiotics include amoxicillin, tmp-smz.
? second-line antibiotics include clarithromycin, azithromycin, amoxicillin-clavulanate, cefuroxime axetil, loracarbef, ciprofloxacin, levofloxacin.
? for patients with uncomplicated acute sinusitis, the less expensive first-line agents appear to be as effective as the

Costlier second-line agents.

Surgery
? surgical drainage indicated
? if intracranial or orbital complications suspected
? for many cases of frontal and sphenoid sinusitis
? for chronic sinusitis recalcitrant to medical therapy
? surgical débridement imperative for treatment of fungal sinusitis

5 people found this helpful