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Overview

Parexel Drop

Manufacturer :  A N Pharmacia
Medicine Composition :  Diazepam, Dicyclomine
Prescription vs OTC : Prescription by Doctor required

About Parexel Drop

This medication is for external use only. Take it in the portion and duration as advised by your doctor. Check the mark and leaflet present inside the box/pack for bearings before use. Keep the item in its original packaging. No special storage conditions are required. Try not to utilize the item after the bottle has been open for more than 1 month. Try not to utilize Parexel Drop after the expiry date which is expressed on the container and bottle after exp. The expiry date alludes to the most recent day of that month. Hold the dropper near the eye without contacting it. Gently squeeze the dropper and place the medication inside the ear.

Parexel Drop is a combination of two medicines: Diazepam and Dicyclomine. Diazepam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Dicyclomine works by relaxing the muscles in your stomach and gut (intestine). It stops sudden muscle contractions (spasms) which in turn relieves cramps, pain, bloating, and discomfort.

This medication has some common adverse effects which can be extraordinary or extreme, relies on the clinical state of the patient. These responses could possibly happen reliably and some of them are remarkable anyway genuine. This is genuinely not an all-out once-over and if you experience any of the below-mentioned infection, contact your specialist immediately. Here are some antagonistic impacts of Parexel Drop which are as per the following: Sleepiness, Confusion, Memory Impairment, Dizziness, Tiredness, and Blurred vision.

    What are the uses of Parexel Drop

    What are the contraindications of Parexel Drop ?

    What are the side effects of Parexel Drop ?

    Key highlights of Parexel Drop

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 3 to 4 days.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 30 to 90 minutes for an oral dose.

    • Are there any pregnancy warnings?

      This medication is extremely unsafe to be used during pregnancy. Studies carried out on humans and animals have shown significant adverse effects on the fetus. Doctor consultation is recommended in such cases.

    • Is it habit forming?

      Habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      The medication should not be consumed by breastfeeding mothers as there is a higher risk of side-effects on the infant. You are suggested to consult your doctor to discuss the potential benefits and risks before taking this medication.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      If you miss a dose of Parexel Drop, take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    How does this medication work?

    Diazepam and Dicyclomine. Diazepam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain. Dicyclomine works by relaxing the muscles in your stomach and gut (intestine). It stops sudden muscle contractions (spasms) which in turn relieves cramps, pain, bloating, and discomfort.

      What are the interactions of Parexel Drop ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Alcohol

        Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Do not perform activities that require mental alertness like driving or operating machinery.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Cetirizine

        Use of Parexel Drop with cetirizine or levocetirizine should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

        Metoclopramide

        Use of Parexel Drop with metoclopramide should be avoided if possible. Do not operate heavy machinery if you are using these medicines. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.

        Opoids

        Opioids like morphine, codeine, tramadol, hydrocodone or any cough preparations containing these medicines should be avoided when you are on Parexel Drop or other benzodiazepines. Appropriate dose adjustments are to be made if coadministration is needed and monitoring of sedation, breathlessness, and hypotension is necessary.

        Azole antifungal agents

        Azole antifungal agents like ketoconazole and itraconazole should be avoided when you are Parexel Drop due to the risk of increased concentrations of the medicine in the body which may cause increased sedation and changes in ECG. Inform the doctor if you are receiving these medicines when you are prescribed with Parexel Drop. If coadministration is needed then alternative medicines like lorazepam and oxazepam could be considered.

        Antihypertensives

        You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
      • Interaction with Disease

        Glaucoma

        Parexel Drop is known to increase the fluid pressure inside the eye. It is contraindicated in acute narrow-angle glaucoma which is an eye disorder.

        Seizures

        The sudden stop of Parexel Drop may cause withdrawal effects and can precipitate seizures. The dose should be reduced gradually. Do not stop taking this medicine without consulting the doctor.
      • Interaction with Food

        Grape fruit juice

        Grapefruit juice should be consumed with Parexel Drop. Alternatively, you can consume orange juice which does not affect the medicine.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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