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Overview

Macox Plus Tablet

Manufacturer :  Macleods Pharmaceuticals Pvt Ltd
Medicine Composition :  Rifampicin, Isoniazid
Prescription vs OTC : Prescription by Doctor not required

About Macox Plus Tablet

Macox tablet belongs to the rifamycin group of antibiotics and is composed of Rifampicin and Isoniazid. It is used to treat bacterial infections. This includes leprosy, tuberculosis and Legionnaires disease.

People with hypersensitivity to this medication are not recommended this medicine. It should be used with caution in people with a history of alcoholism and hepatic and renal impairment.

This medicine is best taken on an empty stomach 1 hour before or 2 hours after a meal. Your dosage will be as prescribed by your doctor where your age, weight and medical condition will be taken into consideration.

    What are the uses of Macox Plus Tablet

    • Tuberculosis

    What are the contraindications of Macox Plus Tablet ?

    What are the side effects of Macox Plus Tablet ?

    Key highlights of Macox Plus Tablet

    • Is It safe with alcohol?

      Interaction with alcohol is unknown. Please consult your doctor.

    • Are there any pregnancy warnings?

      Pregnant women must consult doctor before using this medication.

    • Are there any breast-feeding warnings?

      Breastfeeding women must consult doctor before using this medication.

    • Does this affect kidney function?

      Caution to be advised in patients with impaired renal function.

    What are the substitutes for Macox Plus Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Macox Plus Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

    • Are there any overdose instructions?

      Consult your doctor in case of overdose.

    How does this medication work?

    This medication is composed of Rifampicin and Isoniazid. Rifampicin inhibits bacterial RNA polymerase which is the enzyme responsible for the transcription of DNA. Rifampicin binds and prevents RNA synthesis by blocking elongation and synthesis of bacterial proteins. It blocks the bond between nucleotides in the RNA backbone. Isoniazid is an inactive compound which is known as a prodrug. It needs to be activated by the catalase of bacteria.

      What are the interactions of Macox Plus Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Medicine

        Medicine

        This medication interacts with Pimozide, Warfarin, Leflunomide, Halothane and others.
      • Interaction with Disease

        Disease

        This medication interacts with Peripheral Neuropathy Liver and Kidney Disease.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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