Less RBC is produced by the body when suffering from Thalassemia.
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Thalassemia is a genetic disorder inherited from the parents where the body produces less red blood cells, which in turn means less haemoglobin, and as a result the oxygen carrying capacity of the blood is drastically reduced.
Certain variants of Thalassemics do not need a regular blood transfusion.
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There are two types of Thalassemics: Transfusion Dependant and Non-Transfusion Dependant. The NTDT patients do not require regular blood transfusion except under stressful conditions
Thalassemia is caused due to disorder in the gene causing which of the following?
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Improper globin chain formation leads to formation of defective haemoglobin, which affects the oxygen carrying capacity of the blood.
Which population group has been seen to be most prone to thalassemia?
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African, Middle Eastern and Mediterranean, and South Asian population groups are very susceptible to the thalassemic condition.
Thalassemia is incurable.
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A stem cell therapy like complete bone marrow replacement therapy is the only effective and complete cure for thalassemia. However, it is difficult to find compatible donors for such treatment, and hence regular blood transfusion remains the only effective and viable method to manage thalassemia.
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