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Overview

Tretin Cream

Manufacturer :  Hegde and Hegde Pharmaceutical LLP
Medicine Composition :  Tretinoin
Prescription vs OTC : Prescription by Doctor required

About Tretin Cream

Tretin Cream is prescribed to patients with severe acne problems, photodamaged skin and even some skin cancers. This medication is also known as all-trans retinoic acid and belongs to the group known as retinoids.

This drug, taken in the form of cream or ointment, effectively treats acne. It also reduces the number of pimples that tend to develop, while healing pimples that have already developed on the body. The drug affects skin cell growth in the body regulating the number of pimples that crop up.

This medication should be cautiously used in eczema patients. Excessive exposure to sunlight must be avoided. Also, ensure that it does not get into the eyes. If it does rinse your eyes with water until the irritation stops. If irritation persists call your doctor and seek further advice.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Tretin Cream

    • Acne Vulgaris

    • Wrinkled And Rough/Mottled Skin

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Tretin Cream ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Tretin Cream ?

    • Skin Irritation

    • Burning Or Tingling Sensation Of Skin

    • Red Spots On Skin

    • Peeling And Blistering Of Skin

    • Patchy Appearance Of Skin

    • Erythema

    • Hyperpigmentation

    • Photosensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Tretin Cream

    • How long is the duration of effect?

      The time duration for which this medicine remains effective is not clinically established.

    • What is the onset of action?

      The effect of this medicine can be observed within 2-4 weeks of topical application.

    • Are there any pregnancy warnings?

      Use of this medicine by pregnant women is not recommended.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is not recommended for use by women who are breastfeeding.

    • Is it safe to drive while on this medicine?

      No interaction found or established.

    • Is it safe to drive while on this medicine?

      No interaction found or established.

    • Does this affect kidney function?

      No interaction found or established.

    • Does this affect liver function?

      No interaction found or established.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the substitutes for Tretin Cream ?

    Below is the list of medicines, which have the same composition, strength and form as Tretin Cream , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Apply the missed dose as soon as you remember. If it is almost time for the next scheduled dose then missed dose application can be skipped.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Tretin Cream approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    This medication works by binding to alpha, beta, and gamma retinoic acid receptors (RARs) thus activating them. This produces changes in the gene expression that leads to decreased cell multiplication, inhibition of tumorigenesis and cell differentiation.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Tretin Cream ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Medicine

        Benzoyl Peroxide (Topical)

        Report the use of either of the medicine to the doctor. Your doctor may determine the best course of treatment. Do not stop the use of any medicine without consulting your doctor.

        Salicylic acid (Topical)

        Report the use of either of the medicine to the doctor. Your doctor may determine the best course of treatment. Do not stop the use of any medicine without consulting your doctor.
      • Interaction with Disease

        Eczema

        This medicine should not be used if you are taking medicine for eczema or suffer from a skin abrasion.

        Sunburn

        Use of this medicine on the sunburnt skin should be avoided. Your doctor may prescribe an alternate medicine that is better tolerated.
      • Interaction with Food

        Avoid excessive intake of vitamin A.

      FAQs about Tretin Cream

      • Ques : What is Tretin Cream?

        Ans : This medication is also known as all-trans retinoic acid. The group of medicines that the drug belongs to is known as retinoids. It is prescribed to patients with severe acne problems and some types of skin cancer.

      • Ques : How long do I need to use Tretin Cream before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Tretin Cream?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Tretin Cream empty stomach, before food or after food?

        Ans : This medication should be taken as prescribed by the doctor.

      • Ques : What are the instructions for the storage and disposal of Tretin Cream?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Is it safe to use Tretin Cream?

        Ans : Yes, it is completely safe to use this drug when taken as advised by your doctor.

      • Ques : How long am I supposed to use Tretin Cream?

        Ans : It is advised to take this medication as long as your doctor has prescribed it to you.

      • Ques : I am taking Tretin Cream. What should I do if I am planning to become pregnant?

        Ans : Immediately take medical help if you are planning to become pregnant while being on this drug.

      • Ques : Why does Tretin Cream cause dry skin, dry lips and dry nose?

        Ans : Dryness of skin, nose and lips are some of the common side effects of this medication. Tretin Cream reduces the secretion of oil which results in skin dryness. Apply lip balm to relieve cracked and dry lips. You are also advised to consume enough water to keep our body hydrated.

      References

      • Tretinoin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/tretinoin

      • Tretinoin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00755

      • TRETINOIN cream,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=TRETINOIN

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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