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Overview

Saphrine 1%/0.2% Ointment

Manufacturer :  Group Pharmaceuticals Ltd
Medicine Composition :  Sulfadiazine, Chlorhexidine Gluconate
Prescription vs OTC : Prescription by Doctor required

About Saphrine 1%/0.2% Ointment

Saphrine 1%/0.2% Ointment is used to treat influenza, rheumatic fever with very high temperatures, urinary tract infections. It is used as a preventive antibiotic to inhibit infections in case of severe burns. This medicine belongs to a class of drugs called sulfa antibiotics. However, sometimes this medication will not be very effective in case of viral fever or viral infections.

It is a sulfonamide antibiotic that works by inhibiting para-aminobenzoic acid which is responsible for the synthesis of folic acid inside bacterial cells. This eventually leads to bacterial cell lysis.

Before taking this medication, consult your doctor:

  • if you have any allergies to sulfa medications
  • if you are taking other medicines like anticoagulants, diabetes medication, or any vitamins or diuretics

Use this medication with caution and only after discussing it with your doctor if you have certain metabolic disorders like porphyria or G6PD deficiency, liver or kidney problems, blood disorders like anemia or asthma.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the uses of Saphrine 1%/0.2% Ointment

    • Bacterial Infections

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the contraindications of Saphrine 1%/0.2% Ointment ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the side effects of Saphrine 1%/0.2% Ointment ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    Key highlights of Saphrine 1%/0.2% Ointment

    • Is It safe with alcohol?

      No interaction found

    • Are there any pregnancy warnings?

      This medication may be unsafe to use during pregnancy.

    • Are there any breast-feeding warnings?

      Unknown. Human and animal studies are not available. Please consult your doctor.

    • Is it safe to drive while on this medicine?

      There is no interaction between driving and consuming this drug. So dose alteration is not needed.

    • Does this affect kidney function?

      Caution should be advised in patients with renal impairment.

    • Does this affect liver function?

      There is no data available. Please consult a doctor before consuming the drug.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the substitutes for Saphrine 1%/0.2% Ointment ?

    Below is the list of medicines, which have the same composition, strength and form as Saphrine 1%/0.2% Ointment , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    • Are there any missed dose instructions?

      If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

    How does this medication work?

    This medicine acts as an agent of interference when it comes to bacterial enzyme dihydropteroate synthetase. This bacterial enzyme is required when it comes to the processing of para-aminobenzoic acid (PABA). This is crucial for the synthesis of folic acid in organisms.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a General Uro before using this medicine.

      What are the interactions of Saphrine 1%/0.2% Ointment ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Medicine

        This medicine interacts with the following medication which include Anaesthetics, Anticoagulants, Antidiabetics, Antiepileptics, Antipsychotics, Aspirin, Ciclosporin, Diuretics, Methotrexate, Potassium aminobenzoate, and Probenecid.

      FAQs about Saphrine 1%/0.2% Ointment

      • Ques : What is Saphrine 1%/0.2% Ointment?

        Ans : This medication is used to treat influenza, rheumatic fevers with very high temperatures, urinary tract infections or used as a preventive antibiotic to inhibit infections in case of severe burns.

      • Ques : How long do I need to use Saphrine 1%/0.2% Ointment before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Saphrine 1%/0.2% Ointment?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Saphrine 1%/0.2% Ointment empty stomach, before food or after food?

        Ans : This medication can be applied before or after food as it is for application purpose.

      • Ques : What are the instructions for the storage and disposal of Saphrine 1%/0.2% Ointment?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Sulfadiazine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/sulfadiazine

      • Sulfadiazine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 9 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00359

      • SULFADIAZINE cream,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=SULFADIAZINE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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