Eosinophils are made in bone marrow and circulated to different tissues. The abnormal increase of eosinophils in the body for a longer period is called eosinophilia and it may cause chronic inflammation. The abnormal presence of eosinophils in the urine is known as Eosinophilia. Due to allergic reaction the presence of eosinophils in the urine is seen as acute interstitial nephritis. Eosinophils in urine causes diseases like cystitis, prostatitis, pyelonephritis, and glomerulonephritis, Acute Kidney Injury (AKI).Eosinophils become active due to certain allergic diseases, infections or inflammation. In case of Acute Interstitial Nephritis (AIN), patients may suffer from elevation in creatinine or blood urea nitrogen (BUN).
Physical examination and medical history is studied. Patients may undergo prior tests like Complete Blood Test, Liver function tests (for evidence of hepatic involvement) stool studies – Individuals with a travel history and urinalysis. Based on these tests next procedures are done. You are advised to Inform doctor prior allergies to any medication, any bleeding problems, and about pregnancy.
Detect eosinophils in urine
Urine is collected either by voiding (discharge) or catheterization (facilitates direct drainage of the urinary bladder). Patient may undergo renal ultrasonography (to identify the functions of kidney) for an AIN and gallium scan to study possible infection. In case of severe AKI, patient will undergo kidney biopsy or steroid therapy after the consultation of Nephrologist. Gallium scan: A radioactive tracer (tracer) called gallium citrate is injected into a vein in your arm to study about inflamed tissues present in various organs.
Renal ultrasonography: You are advised to drink plenty of fluids to have a full bladder and can have light meal. You may advised to wear comfortable, loose clothing and also to remove your clothing and dress in a gown that they provide. Kidney biopsy: long thin needle put through the back (flank) into the kidney. The sample can help your doctor to study about the kidney problems. Patient may have to undergo consequences like Bleeding diathesis, Solitary kidney, Patient unable to cooperate with percutaneous procedure, End-stage renal disease with small kidneys, and severe uncontrolled hypertension, Patient refusal, Sepsis or renal parenchymal infection, Antibiotics are given for severe AIN.