Nephrotic syndrome is a group of symptoms that include protein in the urine, low blood protein levels in the blood, high cholesterol levels, high triglyceride levels, and swelling. The swelling may be most noticeable in legs after standing and around the eyes in the morning. Eventually, the swelling of legs may be there all the time, and it may also occur in other parts of the body. Other symptoms include:
• Skin rash or sores
• Foamy appearance of the urine
• Poor appetite
• Weight gain (unintentional) from fluid retention
HOW IS NEPHROTIC SYNDROME DIAGNOSED?
The doctor will perform a physical exam. Laboratory tests will be done to see how well the kidneys are working. They include:
• Albumin blood test
• Blood chemistry tests such as basic metabolic panel or comprehensive metabolic panel
• Blood urea nitrogen (BUN)
• Creatinine - blood test
• Creatinine clearance - urine test
• Kidney biopsy
HOW IS NEPHROTIC SYNDROME TREATED?
The main treatment for nephrotic syndrome is steroids, but additional treatments may also be used if a child develops significant side effects. Most children have relapses until their late teens and need to take steroids when these occur. Nephrotic syndrome can lead to other problems that may need treatment, including high blood pressure, blood clots, and high cholesterol or triglycerides.
DID YOU KNOW?
Nephrotic Syndrome can increase the risk of infections and blood clots.