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The classic symptoms of type 1 diabetes are as follows:
Polyuria
Polydipsia
Polyphagia
Unexplained weight loss
Other symptoms may include fatigue, nausea, and blurred vision.
The onset of symptomatic disease may be sudden. It is not unusual for patients with type 1 diabetes to present with diabetic ketoacidosis (DKA).
Diagnostic criteria by the American Diabetes Association (ADA) include the following:
A fasting plasma glucose (FPG) level ≥126 mg/dL (7.0 mmol/L), or
A 2-hour plasma glucose level ≥200 mg/dL (11.1 mmol/L) during a 75-g oral glucose tolerance test (OGTT), or
A random plasma glucose ≥200 mg/dL (11.1 mmol/L) in a patient with classic symptoms of hyperglycemia or hyperglycemic crisis