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Endace -40Mg Tablet

Manufacturer: Samarth Life Sciences Pvt Ltd
Medicine composition: Megestrol
Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Endace -40Mg Tablet is a synthetic form of the naturally occurring hormone progesterone which is most commonly used as an appetite stimulating agent in the treatment of anorexia and cachexia associated with HIV/AIDS. It is also used as an antineoplastic agent in the palliate treatment of breast cancer or endometrial cancer.

It mimics the action of progesterone by binding to progesterone receptors and stimulates the expression of target genes. Its antitumor properties are because of its progesterone agonist activity, which leads to a decrease in secretion of luteinizing hormone from the pituitary. This in turn leads to a decreased production of estrogen from the ovaries thus impeding the growth of estrogen sensitive tumours.

Endace -40Mg Tablet should not be taken while pregnant or breastfeeding as it may cause harm to the fetus. It should also be avoided if you are allergic to any of its active ingredients or are taking the medication Indinavir (Crixivan).

Some of the most common side effects of the drug include nausea, weight gain, dizziness, difficulty falling asleep, excessive flatulence, spotting in between menstrual cycles and edema. Very high dosages of Endace -40Mg Tablet can lead to symptoms of hypogonadism including decreased secondary sexual characteristics, osteoporosis, and infertility. In severe cases, it may lead to blood clots, diabetes, venous thrombosis, but such cases are rare.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Oncologist before using this medicine.

  • Contraception

  • Is It safe with alcohol?

    Interaction with alcohol is unknown. Please consult your doctor.
  • Are there any pregnancy warnings?

    Megeetron 160mg tablet is highly unsafe to use during pregnancy.
    Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Megeetron 160mg tablet is probably unsafe to use during breastfeeding. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    There is no interaction between driving and consuming this drug. So dose alteration is not needed.
  • Does this affect kidney function?

    Caution should be used in patients with renal impairment.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.

Below is the list of medicines, which have the same composition, strength and form as Endace -40Mg Tablet , and hence can be used as its substitute.

Endace -40Mg Tablet The exact mechanism of action of this drug is unknown, but supposedly, it supresses luteinizing hormone by inhibiting pituitary functions. It also works as an appetite-stimulant and stimulate metabolism. Therefore, it is used in the management of anorexia and cachexia.

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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About Endace -40Mg Tablet
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