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Overview

Myoglobin, Serum Test

Myoglobin, Serum Test

also known as: Urine Myoglobin , Serum Myoglobin

Myoglobin is a protein that is present in your heart and skeletal muscles. It captures the oxygen required for your muscles to function. Occurrence of a heart attack or severe muscle damages leads to the release of myoglobin into the blood stream. The levels of myoglobin increase after 2 to 3 hours after muscle and it peaks about 8 to 12 hours later. This test is administered in the case of a severe muscle injury or cases in which a heart attack is suspected. Symptoms which warrant a myoglobin test include muscle pain, dark coloured urine (too much of myoglobin might lead to a kidney failure), unexplained fever and fatigue, nausea and vomiting, and abdominal pain.

All prior information regarding medication and allergies must be informed. Consumption of any form of drug must be conveyed to the doctor. There is no special preparation required. Wear short sleeved or sleeveless clothes, or you can roll up your sleeves too.

Results are usually less than 90 mcg/ml (micrograms/ milliliter). Higher values often indicate:

  • Exercises which has caused excessive stress
  • Heart Attack
  • Extreme muscle damage like muscular dystrophy (group of diseases that cause the weakening and breakdown of skeletal muscles)
  • Shock
  • Kidney Failure
  • Malignant Hyperthermia (severe reaction to a general anesthetic)
  • Poison and other such foreign substances

Lower values may be due to:

  • Rheumatoid Arthritis ( disorder that affects joints- causing the swelling of joints)
  • Myasthenia gravis (long term neuro- muscular that leads to the weakening of skeletal muscles .

The myoglobin test requires just a blood sample, which is obtained using normal norms. The area, usually accommodating the visible vein on the inside of your hand (near your elbow) is cleaned using an alcohol pad. A thin needle is inserted and the brood is drawn out. The area is then bandaged. The sample is sent for testing the amount of myoglobin present. Since, blood is drawn, there might be a little bleeding or a mild spell of dizziness.

Lacks specificity in diagnosis of acute MI, since increased myoglobin levels occur after intramuscular injections.Increased serum myoglobin has been reported after a high voltage electrical accident.As an index of myocardial infarct, myoglobin returns rapidly to baseline levels.
Specimen
Serum
Volume
0.8ml
Container
Red-top tube or gel-barrier tube.
Type Gender Age-Group Value
Myoglobin
UNISEX
All age groups
<90mcg/L
Average price range of the test is between Rs.800 to Rs.4000 depending on the factors of city, quality and availablity.

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