Arylsulphatase A Test

Arylsulfatase A is an enzyme in our bodies that help break down the sulfatides and it is encoded in the ARSA gene. The test helps measure the amount of the enzyme in the body fluids. It helps to diagnose the genetic disorder called metachromatic leukodystrophy that affects nerves, muscles, and other organs. There are different ways to get the test done – a blood sample, amniotic fluid, urine, or other fluids from the body.

In case of amniotic fluid, you have to make sure that you have gathered all the information from your doctor and are well aware of the process and the medications. You also need to give your consent to your doctor. You also need to tell your doctor your medical history, medications, and if you have had recent surgeries. For the blood test, there is no specific preparation required. You only have to make sure you have gathered all the required information. For the urine test, you might be asked to collect the first urine of the morning. If anything else is required, your doctor would let you know. Depending on your situation and condition, your doctor will advise you with the best course of treatment.

The normal result for the test is 32.0 to 129.6 nanomoles of 4-nitrocatechol/ml of serum/4 hours.

For the test, your doctor will collect the sample and analyse it. For the blood test, your doctor or lab technician will place a plastic band on your upper arm; this is done to fill up the vein with blood and swell up. Then, he or she will clean the area with an antiseptic and put a needle. He will then draw a blood and keep it in a vial or tube. The plastic band and needle are removed and a bandage is applied to the area to stop the bleeding. The whole process usually takes a few minutes. For the other tests, your doctor would let you know the procedure.