Typhoid fever caused by Salmonella typhi is widely recognized as a major public health problem in developing countries. Typhidot is a blood test consisting of an ELISA kit which detects IgM and IgG antibodies against the bacteria Salmonella typhi. The test can show a positive response within 2–3 days of infection. It separately identifies IgM and IgG antibodies. The test determines the presence of specific IgM and IgG antibodies with respect to a 50Kd OMP antigen; that is impregnated on nitrocellulose strips. The presence of IgM indicates recent infection whereas IgG antibodies signify remote infection.