People who handle horses professionally or recreational purposes will effect with horse dander allergy. Some of the horse allergens can be from clothing, domestic dust, horse urine, saliva and equipment. The flakes of horse skin and hair is called dander which the horse sheds like dandruff. Horses has proven to be one of the important and significant allergen sources among all the mammalian allergens. Some of the symptoms are asthma, hives, rashes, itching, sneezing, nasal congestion and runny nose. Horse dander travels long distance in the air.