Cytomegalovirus test (CMV) is used to determine if someone has an active CMV infection. It may also be prescribed to find out if a patient has been infected earlier. CMV virus may cause serious illness and complications in newborns and/or people with weak immune systems such as transplant recipients, cancer patients, people receiving immunosuppressive drugs and people with HIV. The antibody test for this infection is done via a blood test for a molecular method such as polymerase chain reaction (PCR) may be used to detect and measure the amount of viral DNA in a person's sample. Testing can be qualitative, determining the presence or absence of CMV. Symptoms of this infection include fatigue, weakness, sore throat, fever, swollen lymph nodes and muscle cramps.