Long ignored imbalances in the body appear on the surface and are indications of deficiencies in the system. If not properly addressed they can remain and fester and worsen. These stubborn manifestations need not only medications, but a search as to what is deficient in the constitution. This deficiency is then either replaced with supplements, but more long term would be a change in the diet.
Off the top of my head I would suggest one meal be replaced with an intake of just salads - enough greens to satisfy the hunger.