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Kindler's Syndrome - Symptoms + Treatment

Written and reviewed by
Dr. Ankit M Saxena 92% (65 ratings)
Doctor of Medicine (Dermatology, Venereology & Leprosy), MBBS
Dermatologist, Jhansi  •  8 years experience
Kindler's Syndrome - Symptoms + Treatment

Kindler’s Syndrome is a rare skin blistering disease named after Theresa Kindler. It is a kind of skin complication which forms skin blisters and lesions on the mucous membranes. This can happen in any part of your body but mainly concentrates on the area where you have experienced any frictions, bruises or minor trauma, especially on the feet and the hands. In some rare occurrences of Kindler’s Syndrome, it can develop on the internal organs like the food pipe, stomach or the respiratory tract.

This disease generally occurs if you suffer from a disorder called autosomal recessive. It means that you may have inherited an anomalous gene from each parent. It usually happens during childhood and reduces as you age.

Symptoms:
Some of the symptoms of Kindler syndrome are:

  1. Blisters occurring on the body in your infancy and periods of early childhood.
  2. Slowly you will observe altered pigmentation and cutaneous atrophy (A severe dermal condition).
  3. Blistering due to certain skin trauma appearing on the hands and feet.
  4. Some observe abnormalities like dental or ophthalmic
  5. The growth of actinic Keratoses

Treatment:
Kindler’s Syndrome requires a specialized dermatologist for the treatment. In some countries, diagnosis involves skin biopsy. It involves undergoing Immunofluorescence Antigen Mapping or transmission of Electron Microscopy. Blood testing of genes is slowly being developed as a diagnostic test.

Other treatments involve:

  1. A healthy and nutritious diet to heal the disease from within.
  2. Maintaining a good dental hygiene.
  3. Use sunscreen with a high protein formula.
  4. Avoid exposure to the sun as much as possible.
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