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Last Updated: Oct 23, 2019
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Intracytoplasmic Sperm Injection (ICSI) - All You Need To Know!

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Dr. Ruby SehraIVF Specialist • 36 Years Exp.MD / MS - Obstetrtics & Gynaecology, MBBS
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An in vitro fertilisation procedure carried out to counter the problem of male infertility is Intracytoplasmic sperm injection. Male infertility factors include poor quality of sperm, low sperm counts, poor sperm movement or the disability to penetrate an egg. Azoospermia is one such rare condition wherein there is no sperm in the semen. Through this injection, a single sperm can be injected into the egg directly. The fertilised egg is placed into the woman’s uterus or the fallopian tubes. The first successful birth using this procedure was on January 1992 after the conception took place in April 1991.

Collecting Sperm
Sperm can be collected from the male through masturbation. If this procedure somehow fails then sperm can be removed through a surgery. Using a small incision, sperm can be withdrawn from the testicle and is used in the procedure. If the ejaculation of sperm is prevented due to a blockage or if the problem arises in the development of the sperm, surgery method is used.

Injecting the sperm
This is performed through the following steps. A specialised pipette or a glass tube is used to hold the egg, a single sperm is picked with the help of a sharp and delicate needle, the needle is then inserted carefully into the cytoplasm of the egg through the egg shell, then the sperm gets injected into the cytoplasm and the eggs are checked to see whether they have been adequately fertilized.

After this process is done, eggs which are fertilised successfully are selected and placed into the uterus with the help of a catheter. The number of embryos an individual needs to transfer is determined depending on the age of the person and other health issues. For this purpose, a thorough full body check-up is carried out and the medical history is checked during the preliminary consultations.

Expectations from the treatment
The treatment of fertilisation using an Intracytoplasmic sperm injection can be demanding, both physically and mentally for the woman (mother). An individual has to go through regular shots and monitoring including blood tests. There are moments when the shots can be painful for the woman undergoing the procedure.

The reason behind the procedure
When a male is having severe infertility issues, the method of ICSI is helpful. There are times when very little sperm or no sperm ejaculation, the eggs can be fertilised through this procedure. Testing of an embryo for genetic problems is also accomplished through this procedure. When in vitro fertilisation or IVF does not work even after trying repeatedly, then couples can undergo the treatment using ICSI.

Success rate
When ICSI is used along with better quality eggs, it is seen to be successful on many occasions. Especially for men who have sperm ejaculation issues. 

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