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In Vitro Fertilization (IVF) Health Feed

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I have a condition of oligospermia. I have to go for ivf icsi but due to low sperm count and quality doctor is not hopeful for a successful result. I have asked the doctor to wait for a few months so that I can improve my semen quality. There is huge variation between my semen analysis done in an ivf lab and done in pathology lab. Reputed ivf center 1: date: 30/11/17 abs day 3 volume 1 ml sperm count 1 mil/ml motility 5% (progress 1%, non progressive 4%), local pathology lab 1 (this report seems to be incorrect): date 06/04/2019 counts: 15.5 mil/ml, motility: rapid forward progressive 60%, abnormal forms 5% reputed ivf center 2: abs day: 3 volume 2 ml date: 06/07/2019 counts 1 mil / ml, morphology 1%, motility - progressive 15%, non progressive 15%, reputed micro path lab: date: 10/07/2019 abs day: 3 volume 2.59 ml count 3mil/ml total count: 7.77 mil/eja motility at 1 hr: prog+ non progressive 33.3% morphology: 22%, teratozoospermia index: 1.53 sperm deformity index: 1.20 another reputed micro path lab: date: 15/08/19 volume 2.4 ml abs day 3 count 2.1 mil/ml motility: progressive 68%, non prog 16% motile sperm: 1.4 mil / ml prog motile: 1.1 mil / ml there is a huge difference between IVF lab and micro path lab reports. I am confused about which one to trust. As per ivf lab morphology is only 1% so they are afraid to proceed. Hormone test reports as done on 15/08/2019 testosterone 444.26 ng/dl, fsh 17.47 miu/ ml, lh 8.15 miu/ml. Previously an ob-gyn had prescribed me clomifene citrate which I took for around 45 day but it did not increase my sperm counts. Currently I am taking tab. Paternia xt 2 times a day, tab limcee 2 times a day, evion 400 one in evening, n-acetylcysteine 600 mg once daily for around 2 months. It may have improved my semen quality but it has not increased my sperm counts. What can I do to increase my sperm counts and quality? Can I take hcg, hmg or fsh injections? Cost is not a bar as now we can get generics for low cost. Is there any other treatment?

I have a condition of oligospermia. I have to go for ivf icsi but due to low sperm count and quality doctor is not ho...
Hi. All the sperm count does not have a drastic change and it dint match up the who s criteria. Just do a scrotal usg to rule out varicocele if present.
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I am isha rane I am 35 years old. I have 3 miscarriages before. I am an adenomyosis patient and endometriosis too. I want to conceive naturally but Dr. have suggested for ivf. My 1st attempt was failed. Financially we are very weak as we lost our maximum our saving in 1st attempt. Now we cannot offered for another ivf. Please suggest some other way. No ivf no iui.

I am isha rane
I am 35 years old. I have 3 miscarriages before. I am an adenomyosis patient and endometriosis too. I ...
In view of your age and problem ivf gives highest success rate but if can not have same then - any couple desirous of pregnancy and not getting same must meet gynecologist or infertility specialist accepting facts that it needs many reports and different trials of treatment. Means couple must have patience and go to one in whom they have trust to stick for a long time. Also understand and accept extra risk because of age.
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IVF - How To Get Ready For It?

IVF - How To Get Ready For It?

Infertility is known to usher a lot of emotional stress in the lives of those who go through it. Often, an overwhelming sense of grief descends upon the couple who try to grapple with the sense of loss. The social and psychological ambience plays a very important role in reconciling one with the harsh reality and prepping one up for a fresh start. 

While IVF has proven to be a boon in the lives of many couples, many still take to IVF as the last resort. Another factor that makes the responses about IVF rather ambiguous is the uncertainty of the results. There are numerous factors like failure in embryo attachment or uterine incompatibility that often results in a failed IVF. Therefore, before opting for this surgery, one must be mindful of the consequences. 

Some of the ways, one can prepare oneself for IVF have been enlisted below: 

  1. Informed choice: Considering IVF is a rather stressful surgery, one needs to be well aware of the stakes. Reading up about the potential risks and the details about the process, helps one to be prepared for the consequences and deal better with the trauma.
  2. Take good care of your intimate relationships: Since IVF tends to take a toll on not just the mother, but also the close family, it is important to maintain a strong bond of trust and compassion in the course of the surgery. Hostility and discordance add on the stress and sometimes inflict grave health implications upon the mother. It is important to support your partner through the entire journey. You may consider professional counselling too.
  3. Prepare yourself for all possible situations: While the advanced technology aims to minimize any hazard, the results can often be unpredictable. You might want to adequately monitor your cycle in order to anticipate the potential problem areas and the results thereof. You should discuss these with your loved ones to avert excessive stress. It is a good idea to keep oneself productively busy in the due course to avoid anxiety.
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IVF & Tubal Reversal - Know The Difference!

IVF & Tubal Reversal - Know The Difference!

Life is always filled with an unexpected turn of events. Who would love life if the next day can be predicted? But one loves to control certain things in life. One such is having control over the number of kids in the family. Unwanted pregnancies can be stopped by sterilization. Every couple has a plan for the number of kids in the family. You may think you have achieved the target and would love to stay safe. But the family goals can change, and there can be some pressing need for another baby. Do not worry, if you are in the same boat. Your sterilization is not an evergreen end card for pregnancy. It can be reversed. When you want to have a child after tubal sterilization, you can either reverse it or go for IVF. You need to weigh the options, and to do this, you need to know more about them.

Tubal reversal: This is a short stay procedure, mostly an outpatient procedure. The connection between the tubal segments is restored with micro-surgery technique. Any surgery can create complications and here too, the chances of infection and poor tissue healing are there. Damage to the Fallopian tubes, uterus, side walls of the uterus, and ovaries can occur. The recovery time is short, but can extend in case any of these complications arise. There is also a risk of tubal pregnancy. It has to be understood that not all tubal sterilizations can be reversed. When tubal reversal is carried out, your doctor asks to bring the pathology reports of the sterilization process, and also the semen test results of your partner. This is because when sperm count is abnormally low, your chance of getting pregnant is very low. When you rule out the most significant male factor, there are risks of wasting money in reversal and there are health risks involved as well.

IVF: In vitro fertilization (IVF) has brought a ray of hope since the 1970s for women who have problems with the Fallopian tubes. The procedure has gone through modification over years, only to show the success rate accelerating. When there are fertility problems in both the partners, IVF can help in achieving successful childbirth. This is also a sure shot way to get pregnant when the causes of infertility are not known. The sperm and eggs are selected and fused in the laboratory. The fused embryo that results is transferred to the uterus. Tubal bypass occurs here. This means the process that should take place in the tubes is taken care of in the laboratory. The healthiest embryos are chosen for transfer to the uterus, and the success rates are hence higher.

As the tubal bypass happens, you can see this a good option if you have gone for tubal sterilization earlier and want to conceive again. What makes IVF a good choice is the success rate. The tubal reversal simply means that the block is removed. In the case of IVF, an embryo is attached to your uterus. This means there is no beating around the bush. Your chances of getting pregnant are higher multiple times in case of IVF as compared to tubal reversal.

IVF - Know The Myths About It!

IVF - Know The Myths About It!

In vitro fertilization or IVF is deemed as one of the wonder treatments for couples who are facing infertility issues. Whether it is due to poor sperm quality of blocked fallopian tubes, IVF has proven to be a safe and effective solution. However, like with all new techniques, IVF also has some myths which need to be understood before signing up for the procedure. With so much at stake in terms of finances and time, understanding the process will help set realistic expectations and improve the success rate of IVF.

Myth 1: High success rate. While IVF has very high success rates, some women just fail to get pregnant. This could be about 5% of the women and may not be attributable to any particular cause. Each woman responds differently, and failure to conceive through IVF could be due to no explainable cause. What is interesting is that though the first attempt failed, subsequent attempts may be successful. Failing the first cycle does not mean failure in subsequent cycles. Also, success rate differs from clinic to clinic, and so choose one which has a proven track record and good success rates. It should not just have good doctors but also the essential technology and infrastructure to support the IVF technique.

Myth #2: IVF leads to multiple births. While achieving multiple births is easier through IVF, it always does not lead to multiple births. Multiple embryos are implanted, only to improve the chances of success. It does not necessarily translate into multiple births. In women over 38 years of age, it is mandatory to only transfer a single embryo as multiple births are very likely to be complicated.

Myth #3: Rest and time off work. It is believed that IVF has a higher success rate with proper rest and time off work. Rest is definitely required the first few days after embryo transplant but it definitely later assumes a normal course of things. It is not that too much time off work is required, just because you had an IVF. Your body might be different and require more rest, but that could have been the case even with a normal pregnancy.

Myth #4: The medications with IVF are going to have lots of side effects. While the hormones given to promote egg release do have their side effects of making you feel moody and emotional, it is only transient. Once the egg release happens, fertilization is done, and embryo transplant is done, then things should settle down. The effects should wear down once the embryo is implanted and then things should settle down. Of course, pregnancy brings its own hormonal changes, which will run their course through pregnancy.

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I am 38 years, I had a miss carriage, one of my tube was removed, failed 3 ivf, still can I get pregnant.

I am 38 years, I had a miss carriage, one of my tube was removed, failed 3 ivf,
still can I get pregnant.
Yes, though statistically low chance. Any couple desirous of pregnancy and not getting same naturally must meet gynecologist or infertility specialist.
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Natural IVF Or Mini IVF - How Are They Different?

Natural IVF Or Mini IVF - How Are They Different?

Suffering from the problem of infertility can be a heartbreaking as well as a very frustrating process but still with different kinds of IVF treatments available today, a lot of women can realize their dreams of having their own family. In Vitro Fertilization is a laboratory procedure where the sperm and egg are fertilized outside the body.

It has been more than 35 years since the first baby was born through this process of IVF and now it has become the go-to method for treatment regarding reproduction, which assists in the birth of over 5 million babies. With the availability of different kinds of IVF treatments currently, to navigate one’s way through the in vitro fertilization process can seem to be quite confusing as well as intimidating.

Now, we take a look at the difference between the types of IVF treatments and see if they are right for a woman.

Different Types of IVF:

Since the time IVF came into being, more than three decades ago, it has become the leading form of assisted reproduction, having an estimated amount of 70000 babies per year getting conceived through this procedure. The procedure of IVF involves a really complex series of procedures where an egg gets removed from the ovaries of a woman and fertilized with sperm in a laboratory. The fertilized egg, which is called an embryo then, gets returned to the womb of the woman for its growth and development.

Natural Cycle IVF: Natural Cycle IVF bears similarity with the standard IVF treatment but this takes place without having to use medication for stimulating the ovary leading to the preparation of multiple eggs. Natural IVF basically monitors the ovulation cycle of a patient with the intention to retrieve only one egg. This is unlike conventional IVF, which requires retrieval of multiple eggs. Women who opt for Natural IVF due to the process being more economical compared to the traditional treatment. Natural Cycle IVF requires less time as compared to the traditional one and is thought to be a safer as well as stress-free treatment option by certain experts.

Mini IVF: Minimal Stimulation IVF or Mini IVF is a kind of IVF, which is supposed to be somewhere between Natural IVF and Traditional IVF. The Mini IVF treatment is different from the Traditional IVF, with regard to how it gets administered through medicines. In case of Mini IVF treatment, less amount of medication gets administered by the specialists, so that there can only be production of two to three eggs at a time, in comparison to 10 or more in case of conventional IVF.

At the time of treatment, the retrieval of eggs and fertilization take place just like they are done in any other IVF process. The only difference lies in the stimulation part, which is lot less in this case compared to regular In Vitro Fertilization. Despite Mini IVF being suggested as a gentler approach to IVF, some researchers feel that less number of eggs might reduce the possibility of getting success.

Despite the positives, certain fertility experts send out a warning due to the significantly low chance of pregnancy with this process.

Can Endometrial Scratching Boost IVF Success Rates?

Can Endometrial Scratching Boost IVF Success Rates?

In vitro fertilisation (IVF) is a medical procedure followed for those women or couples suffering from infertility or for certain specific genetic problem. In the normal course, women or couples experience positive results within a few IVF cycles. However, in spite of reasonable pregnancy rates, some women may require a few more cycles to achieve pregnancy. In such cases, in order to ensure a healthy pregnancy, the gynaecologist may suggest the women undergo Endometrial Scratching before IVF. 

Endometrium explained in brief: 

The uterus is located in the pelvic region and it is in the size and shape of a pear. The inner cavity of the womb or uterus is protected by the tissue lining called endometrium, also called endometrial. The endometrium plays a significant role in supporting the pregnancy. 

The enhanced success of achieving pregnancy: 

The endometrial scratching procedure is a very simple one, which is resorted, so as to improve the results of IVF procedure. In this procedure, the gynaecologist uses a very fine catheter and makes a small scratch on the endometrial lining. In fact, the scratch causes a kind of inflammatory reaction in the uterus. This inflammatory reaction induces the endometrium to be highly receptive to embryos during the successive menstrual cycle. This added receptivity enhances the success of pregnancy during the next menstrual cycle. 

Considering the higher level of success in achieving pregnancy, the endometrial scratching procedure has gained popularity in the IVF procedure. However, some of the other issues related to endometrial scratching may be as follows: 

  1. Endometrial scratching optimises the uterine lining and thereby, makes it easier to continue the embryo implanting procedure. Normally, before the endometrial scratching procedure, the gynaecologist may suggest an endometrial biopsy. 
  2. The endometrial procedure is usually suggested for those women who had two or more unsuccessful IVF procedures, despite having good quality embryos. However, in some cases, depending on the health of the patient and various other factors, the gynaecologist may suggest this endometrial scratching at the very first IVF procedure. This procedure can be availed either for fresh embryos of the couple or frozen embryos or for the donor egg. 
  3. Although this is a part of a surgical procedure; endometrial scratching is very simple and painless and it is done without administering anesthesia. The procedure does not require any hospitalisation. In fact, the patient can go home soon after the procedure. Except for a few pain killers, this procedure does not require any extensive medication. 

This is a safe and easy procedure. Neither does it lead to any side effects, nor is the procedure burdensome for your wallet. Many couples have been benefited by this endometrial scratching procedure.

Donor Egg - How Can It Contribute To IVF?

Donor Egg - How Can It Contribute To IVF?

Donor egg IVF is used by more than 70 percent of infertile women above 45 years to conceive. More than 8,000 babies are born in the US to women of all age groups by this method of Assistive Reproductive Technologies (ART). This kind of fertility treatment will become even more popular, in the days to come, because of advances in egg-freezing technology.

What are donor eggs
Donor eggs are eggs given by a healthy, fertile woman to an infertile woman for in-vitro fertilisation or IVF.

How does the Donor Egg IVF program work?
Before you start this course of treatment, you must consult your doctor regarding its feasibility and effect on your health. Typically, the process has the following steps;

  1. After a donor has been identified, the infertile woman (referred to as ‘you’) and the donor are given medication so that the menstrual cycles of both are synchronised. You are also given medication so that your endometrium lining is ready for womb transfer.
  2. After their donation, the eggs are fertilised using the In Vitro Fertilization technique.
  3. Since the donor is under 35, not more than three embryos are transferred from her to your womb.
  4. Embryos are formed after fertilising donor egg with partner sperm.

In some cases, the embryos may be transferred after they have been fertilised. This line of treatment is undertaken to reduce the stress of this treatment on you.

In cases of men, the following procedures are followed;

  1. Unless the sperm belongs to another man, your partner will be required to give a sample of his sperm to check sperm quality.
  2. The partner must give another sample on the day the eggs are collected.
  3. In the next stage, the eggs and sperm are mixed together and in vitro fertilised.

Chances of success in Donor Egg IVF program

The chances of you conceiving through this program are 60-70%. This strike rate is significantly higher than a conventional IVF line of treatment.

How to start with Donor Egg IVF program?

  1. Finding an egg donor is not that difficult these days. You can find a donor through a fertility clinic, an egg bank, an egg donation agency, a family member or a close family friend. Donors coming from a frozen egg bank are usually screened for health and other reasons. Most donors are in the age group of 21-35 years.
  2. Make it legal i.e while getting donors is easy, the tricky part is to comply with the various legal issues. Consult your spouse, doctor and your attorney before taking this step.
  3. Get counselling i.e. you need expert counselling before you conceive because, let us face it, your baby is not your biological offspring. You and your spouse need to be adequately psychologically prepared for this important development in the family.
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