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Gestational Trophoblastic - How This Problem Can Be Treated?

Written and reviewed by
Dr. Ekta Singh 90% (42 ratings)
MBBS, MS - Obstetrics and Gynaecology
Gynaecologist, Noida  •  23 years experience
Gestational Trophoblastic - How This Problem Can Be Treated?

Gestational trophoblastic disease is when there are trophoblastic cells which are growing abnormally inside the uterus. It is a pretty rare disease. Gestational trophoblastic disease mostly occurs after conception. The trophoblastic cells are a sort of tumorous cells which surround the fertilized egg in the uterus. It is a very serious and painful condition which can even become cancerous.

Here are the treatments for gestational trophoblastic disease.

  1. HysterectomyA hysterectomy is when the entire uterus is removed from the body using surgery. Hysterectomy is one of the most common methods to cure gestational trophoblastic disease. However, after the hysterectomy, a lot of beta human chorionic gonadotropin blood tests are administered every week. Beta human chorionic gonadotropin blood tests are sometimes shortened to B-HCG blood tests. Patients will also have to visit the doctor for up to 6 months every month following the hysterectomy. However, since a hysterectomy completely removes the uterus, it is probably a last resort option as the baby is kept in the uterus. Chemotherapy and dilation and curettage are perhaps better options if you have gestational trophoblastic disease.
  2. Chemotherapy: Chemotherapy is usually done with one or more anti-cancer drugs. Chemotherapy is continued until the B-HCG or beta human chorionic gonadotropin levels are back to normal. If the chemotherapy does not reduce beta human chorionic gonadotropin levels or the tumor spreads to other parts of the body, then different treatment is required. This includes using chemotherapy for what is known as high-risk metastatic GTN for the gestational trophoblastic disease.
  3. Dilation and curettage: This is a much less drastic procedure and is usually done when the tumor has not spread as much. A D&C which is the short form of dilation and curettage is performed so that the inner parts of the lining of the uterus as well as abnormal tissues are all removed. This is performed by dilating the cervix so that the inner parts of the lining of the uterus as well as the abnormal tissue is all removed. However, a dilation and curettage is safe only when you have a molar pregnancy.

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