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Last Updated: Oct 23, 2019
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Diabetes + Obesity & PCOS - Did You Know It Is The New Epidemic?

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Dr. Ashish KaleGynaecologist • 23 Years Exp.MD - Obstetrics & Gynaecology, Diploma In Endopelvic Surgery, FICS
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PCOS is a common hormonal abnormality seen mostly in reproductive age groups

Affects about 30% females

Diagnosis is by Rotterdam criteria: 2/3 should be present

  • Oligo/anovulation
  • Polycystic ovarian morphology
  • Hyperandrogenism

It also affects other metabolisms like insulin resistance causing diabetes, impaired glucose tolerance and this ultimately exacerbates obesity

  • It has a genetic predisposition.
  • Pcos can either be lean PCOS or obese PCOS.
  • This classification is important to categorize the causal effect and treatment also differs
  • Insulin-mediated glucose disposal reflects the action of insulin on muscle cells and this is decreased by 30-40% in women with PCOS.
  • This is further worsened with obesity.
  • The endogenous glucose production is also affected and this causes glucose intolerance.
  • They also have menstrual irregularities and infertility due to lack of mature egg ( anovulation ) production.

Treatment

  1. Change in lifestyle and diet
  2. Exercise
  3. Weight reduction
  4. Drugs to regularise menses and antidiabetic drugs
  5. Ovulation-inducing agents with or without IUI for subfertility

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