Epidermodysplasia Verruciformis is an autosomal recessive genetic disorder related to the skin. It is commonly referred to as three man illness. People affected with Epidermodysplasia Verruciformis have a high susceptibility towards developing carcinoma of the skin. Also there is greater susceptibility towards human papillomaviruses of the skin. Symptoms are:
• Lifelong eruptions pityriasis versicolor-like macules
• Flat wart-like lesions
• Pink to violet coloured flat-topped papules
• Raised brown colored lesions in sun-exposed skin
HOW IS EPIDERMODYSPLASIA VERRUCIFORMIS DIAGNOSED?
The condition is caused due to genetic disorder and is associated with high carcinoma of the skin. The condition usually appears in the middle age though it can take its onset between the ages 1 to 20.
HOW IS EPIDERMODYSPLASIA VERRUCIFORMIS TREATED?
Currently there is no treatment to prevent new EV lesions from occurring. The management of EV involves a combination of medical and surgical treatments alongside patient counselling and education. Focus on the importance of following sun protection strategies. Treat and remove warts, as one would treat other viral warts. This includes chemical treatment, cryotherapy with liquid nitrogen and electrosurgery. Oral and topical treatments with retinoic are also helpful in treating the disorder.
DID YOU KNOW?
The condition is so called, Lewandowsky-Lutz dysplasia after the names of the physicians Felix Lewandowsky and Wilhelm Lutz, who first documented the condition.